[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100634485":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":25,"locations":31,"responsibleParty":57,"collaborators":18,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":66,"eligibilityCriteria":67,"healthyVolunteers":62,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":18,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":80,"overallStatus":86,"whyStopped":18,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Postgraduate Medical Institute, Lahore","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Dipotassium oxalate pretreatment before composite restoration","EXPERIMENTAL","Participants receive dipotassium oxalate pretreatment before adhesive application and composite restoration.",[13],"Combination Product: Dipotassium Oxalate Gel",{"label":15,"type":16,"description":17,"interventionNames":18},"No Dipotassium Oxalate Pre-treatment, Standard composite filling only","NO_INTERVENTION","Participants receive standard adhesive protocol without dipotassium oxalate pretreatment.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"COMBINATION_PRODUCT","Dipotassium Oxalate Gel","Application of a 3% dipotassium oxalate gel to exposed dentin in non-carious cervical lesions prior to adhesive placement. The material is applied for 90 seconds and gently air-dried without rinsing, following manufacturer instructions. This pretreatment aims to occlude dentinal tubules through calcium oxalate crystal formation before restoration with a standard etch-and-rinse adhesive system and nanohybrid composite resin.",[9],[26],{"name":27,"role":28,"phone":29,"phoneExt":18,"email":30},"Muhammad Usama Bin Sharif BIN SHARIF, BDS","CONTACT","+92 3124244476","osamasharif06@gmail.com",[32],{"facility":33,"status":18,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Punjab Dental Hospital, Lahore","Lahore","Punjab Province","54000","Pakistan","PK",{"type":40,"coordinates":41},"Point",[42,43],74.35071,31.558,{"lat":43,"lon":42},[46,50,51,54],{"name":47,"role":28,"phone":48,"phoneExt":18,"email":49},"Dr. Shazia Naz, BDS, MDS","+923214614543","drshazianaz@demontmorency.edu.pk",{"name":18,"role":28,"phone":18,"phoneExt":18,"email":30},{"name":52,"role":53,"phone":18,"phoneExt":18,"email":18},"MUHAMMAD USAMA BIN SHARIF, BDS","PRINCIPAL_INVESTIGATOR",{"name":55,"role":56,"phone":18,"phoneExt":18,"email":18},"Dr. Shazia Naz, MDS, BDS","SUB_INVESTIGATOR",{"type":53,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Dr. Muhammad Usama Bin Sharif","Principal Investigator","100634485","dipotassium-oxalate-for-postoperative-sensitivity-in-nccls-100634485",false,"NCT07540299","Dipotassium Oxalate for Postoperative Sensitivity in NCCLs","Comparative Evaluation of Dipotassium Oxalate in Postoperative Sensitivity Control in Class V Composite Restorations: A Randomized Controlled Trial","DIPOX-RCT","Inclusion Criteria:\n\n* Individuals aged 30 to 45 years.\n* Presence of at least one tooth with a non-carious cervical lesion (Class V) with a lesion depth of ≥1 mm, requiring restorative treatment.\n* The NCCL must show some symptoms\u002Fsigns of pre-op sensitivity on applying stimulus (i.e Air burst \u002F ethyl chloride spray) and will be recorded.\n* The involved teeth must be vital and show no signs or symptoms of irreversible pulpitis or necrosis.\n* Subjects must be willing to provide written informed consent and commit to the study's follow-up schedule.\n* Subjects with fair to good oral hygiene as determined by a simplified oral hygiene index (OHI-S score ≤2).\n\nExclusion Criteria:\n\n* Presence of carious lesions or restored teeth with existing secondary caries\n* Any tooth with pulpal involvement, previous root canal therapy, or periapical pathology.\n* Teeth with chronic periodontal disease( BPE score 3 and above.).\n* Individuals regularly using Desensitizing toothpastes, NSAIDs, antidepressants, or any other pain-modulating drugs that may alter sensitivity reporting.","ALL","30 Years","45 Years",{"count":72,"type":73},64,"ESTIMATED","INTERVENTIONAL",[76],"NA","Postoperative sensitivity is a common complication following Class V composite restorations, particularly in non-carious cervical lesions (NCCLs). This randomized controlled trial aims to evaluate the effectiveness of dipotassium oxalate as a pre-treatment agent in reducing postoperative sensitivity.\n\nA total of 64 participants will be randomly assigned into two groups: an intervention group receiving dipotassium oxalate prior to adhesive application, and a control group receiving standard adhesive protocol without pretreatment. Sensitivity will be assessed using a Visual Analog Scale (VAS) in response to cold and air stimuli at baseline, 24 hours, 7 days, and 30 days.\n\nThe study aims to determine whether dipotassium oxalate significantly reduces postoperative sensitivity and can be incorporated into routine restorative dental practice.",[79],"Dentin Hypersensitivity, Post Operative Sensitivity Control",[81,82,83,84,85],"Dipotassium Oxalate","Postoperative Sensitivity","Composite Restoration","NCCL","Dentin Hypersensitivity","NOT_YET_RECRUITING","2026-04-18",{"date":89,"type":90},"2026-04-22","ACTUAL",{"date":92,"type":73},"2026-06-01",{"date":94,"type":73},"2026-10-01",{"name":5,"class":6},1]