[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100624324":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":25,"locations":30,"responsibleParty":52,"collaborators":25,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":25,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":25,"enrollmentInfo":64,"targetDuration":25,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":74,"overallStatus":33,"whyStopped":25,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Medical University of South Carolina","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Direct Selective Laser Trabeculoplasty","EXPERIMENTAL","This arm is going to receive the Direct SLT treatment",[13],"Device: Direct Selective laser Trabeculoplasty",{"label":15,"type":16,"description":17,"interventionNames":18},"Traditional Selective Laser Trabeculoplasty","ACTIVE_COMPARATOR","This arm is going to receive the Traditional SLT treatment which will act as a control for the experimental arm. Note that both lasers are Standard of Care (SOC) and FDA approved",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Direct Selective laser Trabeculoplasty","The Direct Selective Laser Trabeculoplasty is a non-contact laser designed to manage IOP in patients with glaucoma. The traditional SLT required a gonioscopy lens to be placed over the patient's eyes to direct the laser towards the trabecular meshwork.",[9,15],null,[27],{"name":28,"affiliation":5,"role":29},"Jella An, MD","PRINCIPAL_INVESTIGATOR",[31],{"facility":32,"status":33,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"MUSC","RECRUITING","Charleston","South Carolina","29407","United States","US",{"type":40,"coordinates":41},"Point",[42,43],-79.93275,32.77632,{"lat":43,"lon":42},[46,51],{"name":47,"role":48,"phone":49,"phoneExt":25,"email":50},"Jella An, MD, MBA","CONTACT","843-792-1443","anjel@musc.edu",{"name":47,"role":29,"phone":25,"phoneExt":25,"email":25},{"type":29,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Jella An","Clinical Professor-Faculty","100624324","direct-vs-standard-slt-for-glaucoma-a-noninferiority-trial-100624324",false,"NCT07408154","Direct vs Standard SLT for Glaucoma: A Noninferiority Trial","A Randomized Controlled Trial Comparing Direct Selective Laser Trabeculoplasty (DSLT) and Selective Laser Trabeculoplasty (SLT) in Reducing Intraocular Pressure in Open-Angle Glaucoma","Inclusion Criteria:\n\n* Age ≥18 years\n* Diagnosis of OAG (including exfoliative or pigmentary) or OHT\n* Gonioscopically open angle (visible scleral spur 360°)\n* Ability to consent and comply with follow-up\n\nExclusion Criteria:\n\n* Angle-closure or secondary glaucomas\n* IOP \\>35 mmHg despite therapy\n* Corneal pathology interfering with laser or IOP measurement\n* Recent ocular surgery (\\\u003C6 months)\n* Contraindications to study medications or procedures\n* Cognitive impairment preventing consent","ALL","18 Years",{"count":65,"type":66},172,"ESTIMATED","INTERVENTIONAL",[69],"NA","This study compares two FDA-approved laser treatments for glaucoma: Direct Selective Laser Trabeculoplasty (DSLT) and Selective Laser Trabeculoplasty (SLT). Both procedures aim to lower eye pressure and prevent vision loss. DSLT is a newer, non-contact technique that may improve comfort and efficiency. Participants will be randomly assigned to receive either DSLT or SLT and followed for 12 months to assess eye pressure, safety, and treatment outcomes.",[72,73],"Open-angle Glaucoma (OAG)","Ocular Hypertension (OHT)",[75,76,77,78,79],"Glaucoma","Open-Angle Glaucoma","Ocular Hypertension","Laser Trabeculoplasty","Intraocular Pressure","2026-05-04",{"date":82,"type":83},"2026-05-06","ACTUAL",{"date":85,"type":83},"2026-04-27",{"date":87,"type":66},"2027-10",{"name":5,"class":6},1]