[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100523515":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":27,"centralContacts":31,"locations":41,"responsibleParty":58,"collaborators":60,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":10,"eligibilityCriteria":70,"healthyVolunteers":71,"sex":72,"minAge":73,"maxAge":10,"enrollmentInfo":74,"targetDuration":77,"studyType":78,"phases":10,"briefSummary":79,"conditions":80,"keywords":84,"overallStatus":44,"whyStopped":10,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Weill Medical College of Cornell University","OTHER",[8,12,15,18,21,24],{"label":9,"type":10,"description":11,"interventionNames":10},"FAP without treatment with NSAIDs",null,"Patients with the Hereditary Cancer Syndrome known as Familial Adenomatous Polyposis (FAP) undergoing upper or lower endoscopy\u002Fsurgery without treatment with NSAIDs",{"label":13,"type":10,"description":14,"interventionNames":10},"FAP on treatment with NSAIDs","Patients with the Hereditary Cancer Syndrome known as Familial Adenomatous Polyposis (FAP) undergoing upper or lower endoscopy\u002Fsurgery on treatment with NSAIDs",{"label":16,"type":10,"description":17,"interventionNames":10},"HNPCC without treatment with NSAIDs","Patients with the Hereditary Cancer Syndrome known as Hereditary Non-Polyposis Colorectal Cancer (HNPCC) undergoing lower endoscopy\u002Fsurgery without treatment with NSAIDs",{"label":19,"type":10,"description":20,"interventionNames":10},"HNPCC on treatment with NSAIDs","Patients with the Hereditary Cancer Syndrome known as Hereditary Non-Polyposis Colorectal Cancer (HNPCC) undergoing lower endoscopy\u002Fsurgery on treatment with NSAIDs",{"label":22,"type":10,"description":23,"interventionNames":10},"Other Hereditary Colorectal Cancer Syndromes","Other Hereditary Colorectal Cancer Syndromes undergoing lower endoscopy\u002Fsurgery",{"label":25,"type":10,"description":26,"interventionNames":10},"Average-risk population","Average-risk population undergoing lower endoscopy\u002Fsurgery in the lower gastrointestinal tract.",[28],{"name":29,"affiliation":5,"role":30},"Steven M Lipkin, MD","PRINCIPAL_INVESTIGATOR",[32,37],{"name":33,"role":34,"phone":35,"phoneExt":10,"email":36},"Steven M Lipkin, MD, PhD","CONTACT","212-746-4014","stl2012@med.cornell.edu",{"name":38,"role":34,"phone":39,"phoneExt":10,"email":40},"Melissa K Frey, MD, MS","646-697-6621","mkf2002@med.cornell.edu",[42],{"facility":43,"status":44,"city":45,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"NYP\u002FWeill Cornell Medicine","RECRUITING","New York","10065","United States","US",{"type":50,"coordinates":51},"Point",[52,53],-74.00597,40.71427,{"lat":53,"lon":52},[56,57],{"name":33,"role":34,"phone":35,"phoneExt":10,"email":36},{"name":33,"role":30,"phone":10,"phoneExt":10,"email":10},{"type":59,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[61],{"name":62,"class":63},"National Cancer Institute (NCI)","NIH","100523515","discovering-new-targets-for-colorectal-and-endometrial-cancer-risk-reduction-100523515",false,"NCT06096688","Discovering New Targets for Colorectal and Endometrial Cancer Risk Reduction","Discovering New Targets for Hereditary and Sporadic Colorectal and Endometrial Cancer Risk Reduction","The following eligibility criteria must be met as follows:\n\n1. Age ≥ 18 years old.\n2. One of the following must be met:\n\n   1. Diagnosis of a Hereditary Cancer Syndrome by positive genetic testing and\u002For clinical criteria to undergo an endoscopy procedure (esophagoduodenoscopy and\u002For colonoscopy\u002Fflexible sigmoidoscopy), or endometrial screening procedure (transvaginal ultrasound and\u002For hysteroscopy and\u002For endometrial biopsy), OR\n   2. Individuals coming to Weill-Cornell Medicine\u002FNYPH to undergo an endoscopy procedure, transvaginal ultrasound, or hysteroscopy for average-risk (population-based) recommendation OR\n   3. Individuals diagnosed with colorectal cancer or endometrial cancer coming to Weill- Cornell Medicine\u002FNYPH for surgical treatment OR\n   4. Individuals coming to Weill-Cornell Medicine\u002FNYPH for care such as, but not limited to, diagnostic testing, clinic and\u002For treatment visit.\n3. Willingness and ability to sign informed consent.\n4. Ability to read\u002Funderstand English, Spanish, and\u002For simplified Chinese.",true,"ALL","18 Years",{"count":75,"type":76},1120,"ESTIMATED","1 Year","OBSERVATIONAL","The primary aim of this study is to collect and store data, tissue, and personal and family histories from patients being screened for colorectal cancer and\u002For endometrial cancer at NYPH and WCM for routine clinical care and to make these available for future use for molecular and mechanistic studies.",[81,82,83],"Colorectal Cancer","Endometrial Cancer","Hereditary Cancer Syndromes",[85,86,87,88,83,89,90,91,92],"personal and family history","genomic\u002Fepigenetic","polyps","carcinomas","mucosa","blood serum markers","chemoprevention","registry","2025-08-26",{"date":95,"type":96},"2025-09-04","ACTUAL",{"date":98,"type":96},"2019-05-29",{"date":100,"type":76},"2026-12-31",{"name":5,"class":6},1]