[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100573672":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":27,"centralContacts":32,"locations":38,"responsibleParty":70,"collaborators":73,"id":77,"slug":78,"hasResults":79,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":24,"eligibilityCriteria":83,"healthyVolunteers":84,"sex":85,"minAge":86,"maxAge":87,"enrollmentInfo":88,"targetDuration":24,"studyType":91,"phases":92,"briefSummary":94,"conditions":95,"keywords":97,"overallStatus":102,"whyStopped":24,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":112},{"fullName":5,"class":6},"Queen's University, Belfast","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"High UPF, high hPDI diet","EXPERIMENTAL","High ultra-processed foods (UPFs) and healthy plant based diet",[13],"Behavioral: High UPF, high hPDI diet",{"label":15,"type":16,"description":17,"interventionNames":18},"Low UPF, high hPDI diet","ACTIVE_COMPARATOR","Low ultra-processed foods (UPFs) and high healthy plant-based diet",[19],"Behavioral: Low UPF, high hPDI diet",[21,25],{"type":22,"name":9,"description":11,"armGroupLabels":23,"otherNames":24},"BEHAVIORAL",[9],null,{"type":22,"name":15,"description":17,"armGroupLabels":26,"otherNames":24},[15],[28],{"name":29,"affiliation":30,"role":31},"Prof. Lorraine Brennan, PhD","University College Dublin","PRINCIPAL_INVESTIGATOR",[33],{"name":34,"role":35,"phone":36,"phoneExt":24,"email":37},"Prof. Jayne Woodside, PhD","CONTACT","+4402890 978942","j.woodside@qub.ac.uk",[39,54],{"facility":30,"status":24,"city":40,"state":41,"zip":42,"country":41,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Dublin","Ireland","D04 C1P1","IE",{"type":45,"coordinates":46},"Point",[47,48],-6.24889,53.33306,{"lat":48,"lon":47},[51],{"name":52,"role":35,"phone":53,"phoneExt":24,"email":24},"Professor Lorraine Brennan, PhD","+353 01 716 6815",{"facility":55,"status":24,"city":56,"state":57,"zip":58,"country":59,"countryCode":60,"cosmosGeoPoint":61,"geoPoint":65,"contacts":66},"Centre for Public Health, Queen's University Belfast","Belfast","Northern Ireland","BT12 6BJ","United Kingdom","UK",{"type":45,"coordinates":62},[63,64],-5.92541,54.59682,{"lat":64,"lon":63},[67],{"name":68,"role":35,"phone":69,"phoneExt":24,"email":37},"Jayne Woodside V Professor, PhD","+44(0)2890 978942",{"type":31,"investigatorFullName":71,"investigatorTitle":72,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Jayne Woodside, PhD","Professor",[74,75],{"name":30,"class":6},{"name":76,"class":6},"Harvard School of Public Health (HSPH)","100573672","dissecting-the-roles-of-high-quality-diets-and-ultra-processed-foods-on-cardiometabolic-health-100573672",false,"NCT06749327","Dissecting the Roles of High-quality Diets and Ultra Processed Foods on Cardiometabolic Health","Ultra-processed Foods, Diet Quality, and Cardiometabolic Health","Inclusion Criteria:\n\n* Men and women aged between 18 and 65 years in general good health with BMI \\\u003C 35 kg\u002Fm2 who can provide informed consent.\n\nExclusion Criteria:\n\n* Participants will be ineligible to enrol if they have diabetes, CVD, any type of cancer (except for basal cell skin cancer), or a condition (pregnancy, breastfeeding, etc) or dietary restriction(s) that would substantially limit their ability to complete the study.\n\nIndividuals will be screened for their adherence to the Plant based diet Index (PDI ).\n\n1. Individuals with low adherence will enter run-in phase only (6 weeks)\n2. Individuals with high adherence will enter the main intervention (4 months)",true,"ALL","18 Years","65 Years",{"count":89,"type":90},330,"ESTIMATED","INTERVENTIONAL",[93],"NA","Controversy remains around the role of ultra-processed food (UPF) consumption and health outcomes. A key question that remains to be answered is: when diet quality is the same, does food processing itself have any independent health effects? The current application aims to isolate the health effects of food processing from those of diet quality through the conduct of a dietary intervention study.",[96],"Cardiometabolic Risk Factors",[98,99,100,101],"Plant-based diets","Diet quality","Cardiometabolic risk factors","Ultra-processed foods","NOT_YET_RECRUITING","2026-05-13",{"date":105,"type":106},"2026-05-18","ACTUAL",{"date":108,"type":90},"2026-10-01",{"date":110,"type":90},"2029-06-01",{"name":5,"class":6},2]