[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100543997":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":19,"locations":28,"responsibleParty":49,"collaborators":10,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":10,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":10,"studyType":65,"phases":10,"briefSummary":66,"conditions":67,"keywords":70,"overallStatus":30,"whyStopped":10,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Sanjay Gandhi Postgraduate Institute of Medical Sciences","OTHER_GOV",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Septic shock",null,"Adult ICU patients having septic shock as defined by Sepsis -3 definition requiring vasopressor for at least 12 hours duration will be considered for inclusion in this observational study..",[13,17],{"name":14,"affiliation":15,"role":16},"Mohan Gurjar, MD, PDCC","Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS)","PRINCIPAL_INVESTIGATOR",{"name":18,"affiliation":15,"role":16},"Dinesh Chandra, MD, DM",[20,24],{"name":14,"role":21,"phone":22,"phoneExt":10,"email":23},"CONTACT","+91-522-249-5403","m.gurjar@rediffmail.com",{"name":25,"role":21,"phone":26,"phoneExt":10,"email":27},"Sanjay Chaudhary, MD","+91-522-249-4540","sanjaychaudhary2282@gmail.com",[29],{"facility":5,"status":30,"city":31,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"RECRUITING","Lucknow","Uttar Pradesh","226014","India","IN",{"type":37,"coordinates":38},"Point",[39,40],80.92313,26.83928,{"lat":40,"lon":39},[43,44,45,46,48],{"name":14,"role":21,"phone":10,"phoneExt":10,"email":10},{"name":18,"role":21,"phone":10,"phoneExt":10,"email":10},{"name":14,"role":16,"phone":10,"phoneExt":10,"email":10},{"name":25,"role":47,"phone":10,"phoneExt":10,"email":10},"SUB_INVESTIGATOR",{"name":18,"role":16,"phone":10,"phoneExt":10,"email":10},{"type":16,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Mohan Gurjar","Professor","100543997","disseminated-intravascular-coagulation-dic-score-and-organ-dysfunction-in-septic-shock-patients-100543997",false,"NCT06363149","Disseminated Intravascular Coagulation (DIC) Score and Organ Dysfunction in Septic Shock Patients","Effect of Disseminated Intravascular Coagulation (DIC) Score Changes on Organ Dysfunction in Septic Shock Patients","Inclusion Criteria:\n\n* Adult ICU patients having septic shock as defined by Sepsis -3 definition requiring vasopressor for at least 12 hours duration will be considered.\n\nExclusion Criteria:\n\n* Patient having septic shock duration either less than 12 hours or more than 24 hours at the time of the inclusion\n* Age less than 18 years or more than 65 years\n* Expected survival less than 72 hours\n* Caregiver refused for the consent to participate in the study","ALL","18 Years","65 Years",{"count":63,"type":64},60,"ESTIMATED","OBSERVATIONAL","Septic shock is common complication in patients with critical illnesses, with higher incidence in low and medium income countries like ours. Disseminated intravascular coagulation (DIC) is also common in patients presenting to intensive care units. Further DIC is common coexisting condition seen in many patients presenting with sepsis and septic shock.\n\nBoth DIC and septic shock individually are associated with very high mortality and morbidity and coexistence of both increase risk manifold. Organ dysfunction is a complication of both septic shock and DIC individually and in presence of coexistence risk further multiply. DIC scoring of every patient at risk as in patients presenting with septic shock help us to predict about patients having more chances to convert to overt DIC.\n\nUnderstanding effects of DIC on organ dysfunction in septic shock patients can help to prognosticate and guide towards early intervention. Also, there is paucity of literature on effect of DIC score changes on organ dysfunction in patients with septic shock.",[68,69],"Septic Shock","Disseminated Intravascular Coagulation",[71,72],"Critical Illnesses","Multiple Organ Dysfunction Syndrome","2025-05-13",{"date":75,"type":76},"2025-05-16","ACTUAL",{"date":78,"type":76},"2024-04-12",{"date":80,"type":64},"2025-09",{"name":5,"class":6},1]