[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100492936":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":30,"locations":40,"responsibleParty":56,"collaborators":25,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":65,"eligibilityCriteria":66,"healthyVolunteers":61,"sex":67,"minAge":68,"maxAge":25,"enrollmentInfo":69,"targetDuration":25,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":78,"overallStatus":42,"whyStopped":25,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Asan Medical Center","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Preemptive distal perfusion group","EXPERIMENTAL","Distal perfusion catheterization will be done within 1 hour after VA-ECMO application.",[13],"Procedure: Distal perfusion catheterization",{"label":15,"type":16,"description":17,"interventionNames":18},"Conventional distal perfusion group","ACTIVE_COMPARATOR","The conventional group will undergo distal perfusion catheterization at the time of limb ischemia sign.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Distal perfusion catheterization","Distal perfusion catheterization will be done within 1 hour after the VA-ECMO application in the preemptive DPC group. The conventional DPC group will undergo distal perfusion catheterization at the time of limb ischemia sign.",[15,9],null,[27],{"name":28,"affiliation":5,"role":29},"Min-Seok Kim","STUDY_CHAIR",[31,36],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Min-Seok Kim, PhD","CONTACT","82-2-3010-3948","msk@amc.seoul.kr",{"name":37,"role":33,"phone":38,"phoneExt":25,"email":39},"Ah-Ram Kim, MD","82-2-3010-0111","ahram3256@amc.seoul.kr",[41],{"facility":5,"status":42,"city":43,"state":25,"zip":44,"country":45,"countryCode":25,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"RECRUITING","Seoul","05505","South Korea",{"type":47,"coordinates":48},"Point",[49,50],126.9784,37.566,{"lat":50,"lon":49},[53,54],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},{"name":37,"role":33,"phone":55,"phoneExt":25,"email":39},"82-2-3010-0169",{"type":57,"investigatorFullName":28,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"SPONSOR_INVESTIGATOR","Clinical Associate Professor","100492936","distal-perfusion-timing-early-or-conservative-to-prevent-limb-ischemia-during-peripheral-va-ecmo-100492936",false,"NCT05698628","Distal Perfusion Timing, Early or Conservative, to Prevent Limb Ischemia During Peripheral VA-ECMO","Comparison Of Conservative Versus Early Distal Perfusion Strategy to Prevent Acute Limb Ischemia in Peripheral Venoarterial Extracorporeal Membrane Oxygenation Patients","DECIDE-ECMO","Inclusion Criteria:\n\n* Age ≥19 years old\n* Refractory cardiogenic shock with peripheral VA-ECMO\n* Informed consent\n\nExclusion Criteria:\n\n* Unwilling or unable to obtain informed consent from the participant or substitute decision-maker\n* Patients who are currently pregnant, postpartum period within 30 days or are breast-feeding\n* VA-ECMO application for causes other than cardiogenic shock\n* Severe coagulopathy\n* Irreversible limb ischemia requiring interventional procedures or surgery at the time of VA-ECMO (previously diagnosed ASO(atherosclerosis obliterans) patients)","ALL","19 Years",{"count":70,"type":71},400,"ESTIMATED","INTERVENTIONAL",[74],"NA","Peripheral VA-ECMO is widely used in refractory cardiogenic shock patients as a salvage therapy. In most cases, the femoral artery and vein are used for the vascular approach. Large cannulas are usually used for proper oxygenation, which may cause peripheral limb ischemia. Distal perfusion catheterization (DPC) at the ipsilateral arterial cannula site is recommended to prevent distal limb ischemia. However, there is no consensus on the proper timing of DPC and additional invasive procedures may cause complications during VA-ECMO support. In this analysis, the investigators compare the clinical outcomes of distal limb ischemia complications between the conventional DPC group (DPC at the time of limb ischemia sign) and the preemptive DPC group (DPC at the time of VA-ECMO application).",[77],"Extracorporeal Membrane Oxygenation Complication",[79,80,81],"Extracorporeal Membrane Oxygenation","Limb ischemia","Cardiogenic shock","2023-06-12",{"date":84,"type":85},"2023-06-15","ACTUAL",{"date":87,"type":85},"2023-04-28",{"date":89,"type":71},"2027-02-28",{"name":28,"class":6},1]