[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100621267":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":33,"locations":32,"responsibleParty":39,"collaborators":43,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":52,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":32,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":70,"overallStatus":74,"whyStopped":32,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":32},{"fullName":5,"class":6},"Lokman Hekim University","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Gamified Mobile Physiotherapy + Center-Based Physiotherapy","EXPERIMENTAL","Participants assigned to the intervention arm will receive center-based physiotherapy three times per week for 8 weeks (45-minute sessions), in combination with a gamified mobile physiotherapy exercise application to be performed at home. The mobile component includes personalised exercise tasks, real-time feedback, and progression-based digital features to support home exercise completion. Participants will be instructed to use the application in accordance with a structured schedule provided by the clinical team.",[13],"Behavioral: Gamified Mobile Physiotherapy Exercise Application",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard Home Exercise + Center-Based Physiotherapy","ACTIVE_COMPARATOR","Participants assigned to the control arm will receive center-based physiotherapy three times per week for 8 weeks (45-minute sessions), in combination with standard home exercise instructions provided by the clinical team. Home exercises are prescribed according to conventional physiotherapy protocols for Duchenne muscular dystrophy and are to be performed without digital support.",[19],"Behavioral: Standard Home Exercise Instructions",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Gamified Mobile Physiotherapy Exercise Application","A mobile gamified exercise program designed for children with Duchenne muscular dystrophy. The program includes personalised exercise tasks, progression-based game features, and feedback to support home-based physiotherapy participation.",[9],[27],"Center-Based Physiotherapy (Behavioral)",{"type":22,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"Standard Home Exercise Instructions","Conventional physiotherapy home exercise instructions provided as written and verbal guidance without digital or gamified components. Exercises are aligned with standard clinical practice for Duchenne muscular dystrophy.",[15],null,[34],{"name":35,"role":36,"phone":37,"phoneExt":32,"email":38},"Başak Çağla Arslan, MSc","CONTACT","+904448548","ptbasakc@gmail.com",{"type":40,"investigatorFullName":41,"investigatorTitle":42,"investigatorAffiliation":5,"oldNameTitle":32,"oldOrganization":32},"SPONSOR_INVESTIGATOR","Başak Çağla Arslan","Lecturer",[44,47,48],{"name":45,"class":46},"Hacettepe University","OTHER",{"name":5,"class":6},{"name":49,"class":46},"Bezmialem Vakif University","100621267","dmd-and-gamified-physiotherapy-100621267",false,"NCT07368400","DMD and Gamified Physiotherapy","Development and Investigation of the Effectiveness of a Gamified Mobile Physical Therapy Exercise Application for Children With Duchenne Muscular Dystrophy: A 6-Month Follow-Up Single-Blind Randomized Controlled Trial","Gamified DMD","Inclusion Criteria:\n\n* Male child aged 6 to 12 years with a confirmed diagnosis of Duchenne muscular dystrophy (DMD) based on specialist evaluation and genetic testing.\n* Vignos lower extremity classification stage 1 or 2.\n* Brooke upper extremity functional classification at least stage 5.\n* Score of 27 or higher on the Modified Mini-Mental Test.\n* Ability to walk independently for at least 6 minutes.\n* Receiving physiotherapy and rehabilitation for at least 8 sessions over a 1-month period.\n* Having regular access to the internet at home.\n* Parent(s) or legal guardian willing to allow the child to participate and able to read and sign the written informed consent form.\n\nExclusion Criteria:\n\n* Presence of any additional diagnosed neurological disorder other than, or in addition to, Duchenne muscular dystrophy.\n* History of any injury and\u002For surgery within the last 6 months.\n* Any cooperation or behavioral problem that prevents completion of the assessment procedures.\n* Difficulty in understanding or speaking Turkish.","MALE","6 Years","12 Years",{"count":62,"type":63},46,"ESTIMATED","INTERVENTIONAL",[66],"NA","Duchenne Muscular Dystrophy (DMD) is a progressive neuromuscular disease that limits children's physical function, mobility, and participation in daily life. Regular physiotherapy and exercise are essential to slow functional decline; however, many children experience difficulties maintaining motivation and adherence to long-term exercise programs. Low adherence leads to reduced treatment benefit and faster loss of motor abilities.\n\nThis study aims to investigate whether a gamified mobile physiotherapy exercise program can improve participation, motivation, and physical outcomes in children with DMD. The mobile program includes personalized exercises designed by physiotherapists and occupational therapists, combined with game-based elements such as rewards, levels, feedback, and virtual achievements to enhance engagement. The program is delivered in addition to face-to-face physiotherapy.\n\nA total of 46 boys aged 6-12 years with a confirmed diagnosis of DMD will be recruited and randomly assigned to either an intervention group or a control group. Both groups will attend an 8-week center-based physiotherapy program. The intervention group will additionally use the gamified mobile exercise application at home, while the control group will receive a standard home exercise program. Participants will be evaluated before treatment, after 8 weeks, and at 6-month follow-up.\n\nThe primary outcomes include physical function, endurance, and mobility. Secondary outcomes include psychosocial well-being, motivation, and therapy participation. The study intends to determine whether gamification-based telerehabilitation can increase adherence, preserve physical abilities, and support participation in children with DMD. If effective, this approach may offer a practical and accessible tool to support long-term rehabilitation needs in this population.",[69],"Duchenne Muscular Dystrophy (DMD)",[71,72,73],"dmd","exercise","gamification","NOT_YET_RECRUITING","2026-01-24",{"date":77,"type":78},"2026-01-27","ACTUAL",{"date":80,"type":63},"2026-05-08",{"date":82,"type":63},"2028-07-05",{"name":41,"class":6}]