[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100641124":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":40,"centralContacts":41,"locations":47,"responsibleParty":90,"collaborators":92,"id":97,"slug":98,"hasResults":99,"nctId":100,"briefTitle":101,"officialTitle":102,"acronym":103,"eligibilityCriteria":104,"healthyVolunteers":99,"sex":105,"minAge":106,"maxAge":40,"enrollmentInfo":107,"targetDuration":40,"studyType":110,"phases":111,"briefSummary":113,"conditions":114,"keywords":122,"overallStatus":132,"whyStopped":40,"lastUpdateSubmitDate":133,"lastUpdatePostDateStruct":134,"startDateStruct":137,"completionDateStruct":139,"leadSponsor":141,"locationsCount":142},{"fullName":5,"class":6},"Heinrich-Heine University, Duesseldorf","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Immediate Digital Workflow \u002F Immediate Implant Placement (Type 1C)","EXPERIMENTAL","Atraumatic tooth extraction and guided implant placement during the same surgical session. Socket management follows the standardized protocol according to defect morphology. Implants are sealed without functional loading and restored with a definitive screw-retained monolithic zirconia crown after healing.",[13],"Procedure: Immediate digital posterior implant workflow",{"label":15,"type":16,"description":17,"interventionNames":18},"Delayed Digital Workflow \u002F Delayed Implant Placement (Type 4B)","ACTIVE_COMPARATOR","Tooth extraction with alveolar ridge preservation as required. Implant placement is performed after approximately 16 weeks of healing using the same surgical and prosthetic protocol. Definitive restoration is delivered after healing following implant placement.",[19],"Procedure: Delayed digital posterior implant workflow",[21,31],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Immediate digital posterior implant workflow","Participants allocated to the immediate digital workflow will undergo atraumatic extraction of a non-restorable posterior tooth followed by immediate implant placement during the same surgical session. Implant placement will be performed using a prosthetically driven digital workflow with static guided surgery. Socket management and sealing of the extraction socket will be performed according to the standardized study protocol and local standard of care. Definitive prosthetic restoration will be delivered after the planned healing period.",[9],[27,28,29,30],"Immediate implant placement","Type 1C implant placement","Immediate digital workflow","Immediate posterior implant rehabilitation",{"type":22,"name":32,"description":33,"armGroupLabels":34,"otherNames":35},"Delayed digital posterior implant workflow","Participants allocated to the delayed digital workflow will undergo atraumatic extraction of a non-restorable posterior tooth followed by alveolar ridge preservation as indicated according to the standardized study protocol and local standard of care. Implant placement will be performed after approximately 16 weeks of healing using a prosthetically driven digital workflow with static guided surgery. Definitive prosthetic restoration will be delivered after the planned healing period.",[15],[36,37,38,39],"Delayed implant placement","Type 4B implant placement","Delayed digital workflow","Delayed posterior implant rehabilitation",null,[42],{"name":43,"role":44,"phone":45,"phoneExt":40,"email":46},"PD Dr. Frank Spitznagel, DMD","CONTACT","+49-211-81-04440","frank.spitznagel@med.uni-duesseldorf.de",[48,71],{"facility":49,"status":40,"city":50,"state":51,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"Department of Prosthodontics, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf, Moorenstraße 5, 40225 Düsseldorf, Germany","Düsseldorf","North Rhine-Westphalia","40225","Germany","DE",{"type":56,"coordinates":57},"Point",[58,59],6.77927,51.22319,{"lat":59,"lon":58},[62,64,66,69],{"name":63,"role":44,"phone":45,"phoneExt":40,"email":46},"PD Dr. Frank Spitznagel, DMD, PhD",{"name":43,"role":65,"phone":40,"phoneExt":40,"email":40},"PRINCIPAL_INVESTIGATOR",{"name":67,"role":68,"phone":40,"phoneExt":40,"email":40},"Dr. Patrick Klein, DMD","SUB_INVESTIGATOR",{"name":70,"role":68,"phone":40,"phoneExt":40,"email":40},"Prof. Dr. Petra Gierthmühlen, DMD",{"facility":72,"status":40,"city":73,"state":40,"zip":40,"country":73,"countryCode":74,"cosmosGeoPoint":75,"geoPoint":79,"contacts":80},"The University of Hong Kong Department of Periodontology and Implant Dentistry, Faculty of Dentistry Prince Philip Dental Hospital","Hong Kong","HK",{"type":56,"coordinates":76},[77,78],114.17469,22.27832,{"lat":78,"lon":77},[81,85,86,88],{"name":82,"role":44,"phone":83,"phoneExt":40,"email":84},"Prof. Melissa Fok, DMD","+852 2859 0301","melfok@hku.hk",{"name":82,"role":65,"phone":40,"phoneExt":40,"email":40},{"name":87,"role":68,"phone":40,"phoneExt":40,"email":40},"Prof. George Prof. Pelekos, DMD",{"name":89,"role":68,"phone":40,"phoneExt":40,"email":40},"Dr. Dominic Ho, DMD",{"type":91,"investigatorFullName":40,"investigatorTitle":40,"investigatorAffiliation":40,"oldNameTitle":40,"oldOrganization":40},"SPONSOR",[93,95],{"name":94,"class":6},"The University of Hong Kong",{"name":96,"class":6},"ITI International Team for Implantology, Switzerland","100641124","do-immediate-digital-workflows-increase-patient-value-100641124",false,"NCT07656597","Do Immediate Digital Workflows Increase Patient Value?","Do Immediate Digital Workflows Increase Patient Value? A Patient-Reported Outcome Measure-Based Randomized Controlled Trial Comparing Immediate Versus Delayed Digital Posterior Implant Workflows","ITI PROM RCT","Inclusion Criteria:\n\n* Adults aged 18 years or older.\n* Indication for single implant therapy in a posterior premolar or molar extraction site.\n* Good oral hygiene with FMPS ≤20%.\n* Controlled periodontitis according to protocol definition.\n* At least one natural tooth adjacent to the implant site and presence of an antagonist tooth.\n* Ability to comply with study procedures and provide written informed consent.\n* Adequate bone volume for immediate or delayed placement.\n* Extraction site suitable for centrally positioned, prosthetically driven implant placement using straight prosthetic components.\n* Ability to achieve 3-4 mm circumferential implant engagement in native bone along the planned implant axis while maintaining safety distance from vital structures.\n* For molar sites, septal bone classified as Smith \\& Tarnow Type A or Type B, including cases requiring closed sinus floor elevation.\n* Post-extraction socket presenting as a contained or partially contained defect with at least three relatively intact socket walls and no individual socket wall vertical defect \\>5 mm.\n* No facial soft-tissue dehiscence or mucogingival defect associated with buccal bone dehiscence.\n\nExclusion Criteria:\n\n* • Known or suspected poor compliance, alcohol abuse, or substance abuse.\n\n  * Systemic or local contraindications to implant surgery.\n  * History of head\u002Fneck radiotherapy or recent malignancy within 5 years.\n  * Use of medications affecting bone metabolism.\n  * Bisphosphonate use within the past 5 years.\n  * Uncontrolled periodontal disease.\n  * Heavy smoking (\\>10 cigarettes\u002Fday).\n  * Pregnancy or lactation.\n  * Teeth with periapical lesions \\>5 mm in greatest diameter, or sockets demonstrating a large cortical perforation \\>5 mm in greatest dimension on CBCT.","ALL","18 Years",{"count":108,"type":109},50,"ESTIMATED","INTERVENTIONAL",[112],"NA","This two-center randomized controlled trial will evaluate whether an immediate digital posterior implant workflow provides greater patient-defined value than a delayed digital workflow in adults requiring single posterior implant rehabilitation. Participants will be randomized 1:1 to immediate implant placement at the time of tooth extraction or to delayed implant placement after approximately 16 weeks of healing following extraction and ridge preservation as indicated. The primary endpoint is oral health-related quality of life assessed longitudinally using the OHIP-14 questionnaire and analyzed as the model-based mean score averaged across the active treatment phase from baseline through definitive crown delivery. Secondary outcomes include workflow-related patient experience, chairside time, number of visits, postoperative pain, buccal contour changes based on intraoral scan-derived volumetric analysis, radiographic marginal bone level changes, implant survival, clinical peri-implant parameters, technical complications, esthetic outcomes, accuracy of guided implant placement, and clinician-reported workflow outcomes.",[115,116,117,118,119,120,121],"Dental Implant","Implant Therapy","Immediate Dental Implant Placement","Delayed Implant","Guided Surgery Accuracy","Patient-Reported Outcomes (PRO)","Single Tooth Dental Implant",[115,123,124,125,126,127,128,129,130,131],"immediate implant placement","delayed implant placement","digital workflow","guided surgery","patient-reported outcomes","OHIP-14","posterior implant rehabilitation","chairside time","volumetric analysis","NOT_YET_RECRUITING","2026-06-15",{"date":135,"type":136},"2026-06-18","ACTUAL",{"date":138,"type":109},"2026-08-03",{"date":140,"type":109},"2028-10-31",{"name":5,"class":6},2]