[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100293170":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":33,"locations":38,"responsibleParty":55,"collaborators":58,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":26,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":26,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":81,"overallStatus":41,"whyStopped":26,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"The University of Texas Health Science Center, Houston","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Physical therapy (PT) plus blood flow restriction (BFR)","EXPERIMENTAL","Physical therapy consists of two or three 90-minute sessions per week for 6 weeks and a minimum of 18 visits required for study inclusion. With BFR, exercises will be performed at 30% one-rep max with the BFR cuff placed around the proximal thigh and inflated to 80% of limb occlusion pressure (avg: 150 mmHg).",[13,14],"Device: Blood flow restriction","Other: Physical therapy",{"label":16,"type":17,"description":18,"interventionNames":19},"Physical therapy","ACTIVE_COMPARATOR","Physical therapy consists of two or three 90-minute sessions per week for 6 weeks and a minimum of 18 visits required for study inclusion.",[14],[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Blood flow restriction","With BFR, exercises will be performed at 30% one-rep max with the BFR cuff placed around the proximal thigh and inflated to 80% of limb occlusion pressure (avg: 150 mmHg).",[9],null,{"type":6,"name":16,"description":18,"armGroupLabels":28,"otherNames":26},[16,9],[30],{"name":31,"affiliation":5,"role":32},"Walter R Lowe, MD","PRINCIPAL_INVESTIGATOR",[34],{"name":31,"role":35,"phone":36,"phoneExt":26,"email":37},"CONTACT","713-486-6844","walter.r.lowe@uth.tmc.edu",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"The University of Texas Health Science Center at Houston","RECRUITING","Houston","Texas","77030","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-95.36327,29.76328,{"lat":51,"lon":50},[54],{"name":31,"role":35,"phone":36,"phoneExt":26,"email":37},{"type":32,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Walter R Lowe","Professor and Chair",[59],{"name":60,"class":6},"Memorial Hermann Hospital","100293170","does-blood-flow-restriction-training-improve-quadriceps-function-after-arthroscopic-knee-surgery-100293170",false,"NCT03096366","Does Blood Flow Restriction Training Improve Quadriceps Function After Arthroscopic Knee Surgery?","Does Blood Flow Restriction Training Improve Quadriceps Function After Arthroscopic Knee Surgery? A Randomized Clinical Trial","Inclusion Criteria:\n\n* Anterior cruciate ligament (ACL) reconstruction with concomitant meniscus or cartilage restoration procedures\n* Adherence to modified weight bearing status before initiation of PT\n* Expected participation in recreational or competitive sports after release to full activities\n\nExclusion Criteria:\n\n* Unable to attend (or participate in) physical therapy\n* Pregnancy\n* Malignancy\n* Fracture\n* Peripheral vascular disease\n* History of deep vein thrombosis (DVT)","ALL","14 Years","55 Years",{"count":72,"type":73},150,"ESTIMATED","INTERVENTIONAL",[76],"NA","The purpose of this study is to evaluate the effectiveness of physical therapy (PT) plus BFR training compared to PT alone (without BFR training) after ACL reconstruction in patients who require extended limited weight bearing through assessment of patient reported outcomes and functional testing. The hypothesis is that PT plus BFR training will mitigate the loss of quadriceps muscle cross-sectional area, strength, and function while also improving early clinical and functional results.",[79,80],"Quadriceps Atrophy","ACL Reconstruction",[82],"anterior cruciate ligament reconstruction","2022-05-03",{"date":85,"type":86},"2022-05-04","ACTUAL",{"date":88,"type":86},"2017-11-21",{"date":90,"type":73},"2022-12",{"name":5,"class":6},1]