[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100574106":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":40,"responsibleParty":78,"collaborators":26,"id":81,"slug":82,"hasResults":83,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":87,"eligibilityCriteria":88,"healthyVolunteers":83,"sex":89,"minAge":90,"maxAge":26,"enrollmentInfo":91,"targetDuration":26,"studyType":94,"phases":95,"briefSummary":97,"conditions":98,"keywords":100,"overallStatus":104,"whyStopped":26,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":114},{"fullName":5,"class":6},"University of British Columbia","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Biopsy Alone","ACTIVE_COMPARATOR","Patients in this group will only undergo sural nerve and muscle biopsy",[13],"Procedure: Biopsy Alone",{"label":15,"type":16,"description":17,"interventionNames":18},"Biopsy and RPNI","EXPERIMENTAL","Patients in this group will undergo RPNI during their sural nerve and muscle biopsy",[19],"Procedure: Peripheral Nerve Regenerative Interface (RPNI) and Nerve\u002FMuscle Biopsy",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Peripheral Nerve Regenerative Interface (RPNI) and Nerve\u002FMuscle Biopsy","RPNI is a surgical technique which wraps denervated muscle targets around severed nerve ends.",[15],null,{"type":22,"name":9,"description":28,"armGroupLabels":29,"otherNames":26},"Sural nerve and muscle biopsy performed in the standard fashion.",[9],[31],{"name":32,"affiliation":5,"role":33},"Jenna-Lynn Senger, MD","PRINCIPAL_INVESTIGATOR",[35],{"name":36,"role":37,"phone":38,"phoneExt":26,"email":39},"Danielle Cohen, MD","CONTACT","7782236829","cohen6@student.ubc.ca",[41,59,68],{"facility":42,"status":26,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"UBC Division of Plastic Surgery","Vancouver","British Columbia","V5Z1M9","Canada","CA",{"type":49,"coordinates":50},"Point",[51,52],-123.11934,49.24966,{"lat":52,"lon":51},[55],{"name":56,"role":37,"phone":57,"phoneExt":26,"email":58},"Zaima Chowdhury","604-446-683","zaima.chowdhury@vch.ca",{"facility":60,"status":26,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":61,"geoPoint":63,"contacts":64},"Vancouver General Hospital",{"type":49,"coordinates":62},[51,52],{"lat":52,"lon":51},[65,67],{"name":56,"role":37,"phone":66,"phoneExt":26,"email":58},"604-446-6831",{"name":36,"role":37,"phone":26,"phoneExt":26,"email":26},{"facility":69,"status":26,"city":43,"state":44,"zip":70,"country":46,"countryCode":47,"cosmosGeoPoint":71,"geoPoint":73,"contacts":74},"Saint Pauls Hospital","V6Z 1Y6",{"type":49,"coordinates":72},[51,52],{"lat":52,"lon":51},[75,76],{"name":56,"role":37,"phone":66,"phoneExt":26,"email":58},{"name":77,"role":37,"phone":26,"phoneExt":26,"email":26},"Jenna-Lynn Senger",{"type":33,"investigatorFullName":79,"investigatorTitle":80,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Danielle Cohen","Resident","100574106","does-rpni-reduce-incidence-of-neuroma-formation-following-sural-nerve-biopsy-100574106",false,"NCT06754969","Does RPNI Reduce Incidence of Neuroma Formation Following Sural Nerve Biopsy","Does RPNI Reduce Incidence of Neuroma Formation Following Sural Nerve Biopsy: a Pilot Study","NBxPilot","Inclusion Criteria:\n\n* Patient 18 years old and older who are referred for sural nerve and muscle biopsy to the University of British Columbia Division of Plastic Surgery from January 2025 onwards for diagnostic or prognostic clarification of a medical condition.\n\nExclusion Criteria:\n\n* Patients with previous nerve trauma (traumatic injury, surgery, or repeat biopsy) of biopsied nerve.","ALL","18 Years",{"count":92,"type":93},20,"ESTIMATED","INTERVENTIONAL",[96],"NA","The purpose of our project is to determine if incorporating preventative surgical techniques such as regenerative peripheral nerve interfaces (RPNI) into sural nerve biopsy can reduce the incidence of symptomatic neuroma formation. Findings from this study will inform best practice guidelines and can dramatically impact patient care, improve patient quality of life, and reduce the number of required repeat operations.",[99],"Neuroma of Lower Limb",[101,102,103],"Sural Nerve Biopsy","Regenerative Peripheral Nerve Biopsy","RPNI","NOT_YET_RECRUITING","2024-12-23",{"date":107,"type":108},"2025-01-01","ACTUAL",{"date":110,"type":93},"2025-03",{"date":112,"type":93},"2026-12",{"name":5,"class":6},3]