[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100574338":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":49,"collaborators":25,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":25,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":25,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":25,"overallStatus":73,"whyStopped":25,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Assiut University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"CTGT group","EXPERIMENTAL","a clinically guided resuscitation protocol, derived from EGDT",[13],"Procedure: a clinically guided resuscitation protocol,",{"label":15,"type":10,"description":16,"interventionNames":17},"ECHO group","a transthoracic bedside focused echocardiographic assessment of the patient",[18],"Procedure: a transthoracic bedside focused echocardiographic assessment",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","a clinically guided resuscitation protocol,","a clinically guided resuscitation protocol, derived from EGDT and modified to match with the latest survival sepsis campaign guidelines",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"a transthoracic bedside focused echocardiographic assessment","a transthoracic bedside focused echocardiographic assessment of the patient will be done, as a baseline ECHO in a three-step approach to monitor hemodynamics using Logiq P7, S5-1 ECHO probe;",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Ghada Abo Elfadl, MD","CONTACT","01005802086","ghadafadl77@gmail.com",[37],{"facility":38,"status":25,"city":39,"state":25,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":25},"woman health hospital , Assiut university","Asyut","71515","Egypt","EG",{"type":44,"coordinates":45},"Point",[46,47],31.18368,27.18096,{"lat":47,"lon":46},{"type":50,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Ghada Mohammed AboelFadl","Principal investigator","100574338","doppler-echocardiography-versus-clinical-targets-guided-therapy-on-the-outcome-of-postpartum-septic-shock-100574338",false,"NCT06757985","Doppler Echocardiography Versus Clinical Targets Guided Therapy on the Outcome of Postpartum Septic Shock.","Doppler Echocardiography Versus Clinical Targets Guided Therapy on the Outcome of Postpartum Septic Shock, a Randomized Controlled Trial","Inclusion Criteria:\n\n* postpartum women, within 6 weeks following delivery\n* meeting the third international consensus definitions for septic Shock (2016) (Sepsis-3): acute persisting hypotension requiring vasopressors to maintain mean arterial pressure (MAP) ≥ 65 mm Hg and having a serum lactate \\> 2 mmol\u002FL (18 mg\u002FdL) despite adequate volume resuscitation\n\nExclusion Criteria:\n\n* Patient refusal\n* History of any chronic cardiac disease\n* Requirement for immediate surgery\n* Hypotension attributable to another cause\n* Do-not-resuscitate status\n* Contraindication to central venous catheter placement\n* Difficult transthoracic echocardiographic evaluation\n* Primary cardiogenic cause of shock, instead of sepsis.","FEMALE","18 Years","45 Years",{"count":64,"type":65},60,"ESTIMATED","INTERVENTIONAL",[68],"NA","Postpartum sepsis is widely known as a preventable main cause of maternal morbidity and mortality. According to the World Health Organization, approximately 11% of the estimated maternal deaths worldwide were attributed to sepsis. Recent global assessments indicate that obstetric infections rank as the third most prevalent cause of maternal death, with a prevalence mainly observed in low- and middle-income nations.",[71,72],"Doppler Echocardiography","Postpartum Septic Shock","NOT_YET_RECRUITING","2025-01-03",{"date":76,"type":77},"2025-01-06","ACTUAL",{"date":79,"type":65},"2024-12-30",{"date":81,"type":65},"2026-11-30",{"name":5,"class":6},1]