[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100597450":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":10,"locations":10,"responsibleParty":12,"collaborators":10,"id":14,"slug":15,"hasResults":16,"nctId":17,"briefTitle":18,"officialTitle":19,"acronym":10,"eligibilityCriteria":20,"healthyVolunteers":16,"sex":21,"minAge":22,"maxAge":10,"enrollmentInfo":23,"targetDuration":10,"studyType":26,"phases":10,"briefSummary":27,"conditions":28,"keywords":30,"overallStatus":33,"whyStopped":10,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":10},{"fullName":5,"class":6},"Beijing Tsinghua Chang Gung Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Successful downstaging",null,"Failure downstaging",{"type":13,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100597450","downstaging-prediction-model-for-hcc-100597450",false,"NCT07058649","Downstaging Prediction Model for HCC","Individualized Downstaging Prediction Model for HCC Beyond the UCSF Criteria","Inclusion Criteria:\n\n* (A) Adult patients with HCC over the age of 18 (clinically diagnosed or pathologically diagnosed); (B) Liver function Child-Pugh score of Class A, or Class B with a score of 7 or below (including 7); (C) A single solid tumor with a diameter of ≥6.5 cm; three or more lesions, among which at least one tumor has a diameter \\>4.5 cm or the sum of the diameters is ≥8 cm; invasion of major blood vessels regardless of tumor size and number.\n\nExclusion Criteria:\n\n* (A) Presence of distant metastasis outside the liver; (B) General performance status score (PS score) greater than 2 points.","ALL","18 Years",{"count":24,"type":25},369,"ESTIMATED","OBSERVATIONAL","This study is a real-world, single-center study that collects imaging and clinical data from patients with HCC who are downstaged beyond the UCSF criteria.",[29],"HCC - Hepatocellular Carcinoma",[31,32],"downstaging","UCSF","NOT_YET_RECRUITING","2025-07-01",{"date":36,"type":37},"2025-07-10","ACTUAL",{"date":39,"type":25},"2025-07-16",{"date":41,"type":25},"2027-12-01",{"name":5,"class":6}]