[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100594688":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":19,"locations":25,"responsibleParty":43,"collaborators":10,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":10,"eligibilityCriteria":53,"healthyVolunteers":49,"sex":54,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":10,"studyType":60,"phases":10,"briefSummary":61,"conditions":62,"keywords":66,"overallStatus":27,"whyStopped":10,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":73,"leadSponsor":75,"locationsCount":76},{"fullName":5,"class":6},"Cairo University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Doxapram",null,"All patients will receive doxapram during spontaneous breathing trial",[13],"Drug: Doxapram",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":10},"DRUG","Doxapram will be given as 1.5 mg\u002Fkg will be given 10 minutes after the initiation of SBT",[9],[20],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Mina Helmy, MD","CONTACT","+201007174836","dr_mina20002010@yahoo.com",[26],{"facility":5,"status":27,"city":28,"state":29,"zip":30,"country":31,"countryCode":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"RECRUITING","Cairo","Cairo Governorate","6890","Egypt","EG",{"type":34,"coordinates":35},"Point",[36,37],31.24967,30.06263,{"lat":37,"lon":36},[40],{"name":5,"role":22,"phone":41,"phoneExt":10,"email":42},"01007174836","kasralainirec@gmail.com",{"type":44,"investigatorFullName":45,"investigatorTitle":46,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Mina Adolf Helmy","Lecturer of anesthesia and critical care","100594688","doxapram-administration-on-diaphragmatic-excursion-in-mechanically-ventilated-patients-with-chronic-obstructive-pulmonary-disease-undergoing-spontaneous-breathing-trial-100594688",false,"NCT07022704","Doxapram Administration on Diaphragmatic Excursion in Mechanically Ventilated Patients With Chronic Obstructive Pulmonary Disease Undergoing Spontaneous Breathing Trial","The Influence of Doxapram Administration on Diaphragmatic Excursion in Mechanically Ventilated Patients With Chronic Obstructive Pulmonary Disease Undergoing Spontaneous Breathing Trial: a Prospective Observational Study","Inclusion Criteria:\n\n* Patients with moderate to severe chronic obstructive pulmonary disease undergoing spontaneous breathing trial\n\nExclusion Criteria:\n\n* Refusal Allergy to doxapram neuromuscular disorders inability to evaluate the diaphragm","ALL","20 Years","65 Years",{"count":58,"type":59},35,"ESTIMATED","OBSERVATIONAL","Researchers aim to evaluate the impact of doxapram administration on diaphragmatic excursion in chronic obstructive pulmonary disease (COPD) patients undergoing spontaneous breathing trial",[63,64,65],"COPD","Mechanical Ventilation","Weaning From Mechanical Ventilation",[63,9,67],"Diaphragmatic excursion","2025-06-22",{"date":70,"type":71},"2025-06-26","ACTUAL",{"date":68,"type":59},{"date":74,"type":59},"2025-11-01",{"name":5,"class":6},1]