[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100480469":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":29,"centralContacts":33,"locations":39,"responsibleParty":56,"collaborators":58,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":66,"acronym":10,"eligibilityCriteria":67,"healthyVolunteers":68,"sex":69,"minAge":70,"maxAge":10,"enrollmentInfo":71,"targetDuration":10,"studyType":74,"phases":10,"briefSummary":75,"conditions":76,"keywords":80,"overallStatus":42,"whyStopped":10,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"New York Stem Cell Foundation Research Institute","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Parkinson's Disease",null,"Subjects in this group will have a diagnosis of Parkinson's disease with or without a known GBA gene mutation.",[13],"Other: Biological Sample Collection",{"label":15,"type":10,"description":16,"interventionNames":17},"Gaucher Disease","Subjects in this group with have a diagnosis of Gaucher disease with or without a known GBA gene mutation.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Healthy Control","Subjects in this group will serve as healthy controls.",[13],[23],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":27},"Biological Sample Collection","Skin biopsy (2-3mm) and\u002For blood (up to 50 mL); saliva; excess\u002Fleftover biospecimens that were (or will be) collected for other purposes (e.g., medical procedure)",[15,19,9],[28],"Biological sample collection for biobanking and research",[30],{"name":31,"affiliation":5,"role":32},"Laura Andres-Martin","PRINCIPAL_INVESTIGATOR",[34],{"name":35,"role":36,"phone":37,"phoneExt":10,"email":38},"Clinical Research Office","CONTACT","212-927-1801","clinicalresearch@nyscf.org",[40],{"facility":41,"status":42,"city":43,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"The New York Stem Cell Foundation Research Institute","RECRUITING","New York","10019","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-74.00597,40.71427,{"lat":51,"lon":50},[54,55],{"name":35,"role":36,"phone":37,"phoneExt":10,"email":38},{"name":31,"role":32,"phone":10,"phoneExt":10,"email":10},{"type":57,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[59],{"name":60,"class":61},"Silverstein Foundation","UNKNOWN","100480469","drug-discovery-for-parkinsons-with-mutations-in-the-gba-gene-100480469",false,"NCT05536388","Drug Discovery for Parkinson's With Mutations in the GBA Gene","Inclusion Criteria:\n\n* Age 18 years or older.\n* Diagnosis of Parkinson's disease, Gaucher disease, or healthy control.\n* Must provide written informed consent unless physical limitations preclude signing.\n\nExclusion Criteria:\n\n* For skin samples collected specifically for this study: history of keloid formation, coagulation disorder, allergy to the anesthetic, or anticoagulation use that precludes sample collection.\n* For blood samples collected specifically for this study: coagulation disorder or other medical condition(s) that increases the risks associated with blood collection.\n* For all prospective sample collections: Subjects who refuse to adhere to NYSCF's and\u002For a collection site's safety protocols will be excluded. Subjects with an AIDS diagnosis and CD4 count of less than 200 cells per microliter (mcL) of blood will be excluded due to increased risk of infection.",true,"ALL","18 Years",{"count":72,"type":73},60,"ESTIMATED","OBSERVATIONAL","The New York Stem Cell Foundation (NYSCF) Research Institute is performing this research to accelerate Parkinson's disease research and drug development by using cells from the body (such as skin or blood cells) to make stem cells and other types of cells, conduct research on the samples, perform genetic testing, and\u002For store the samples for future use.\n\nThrough this research, researchers hope to identify future treatments or even cures for Parkinson's disease.",[77,15,78,79],"Parkinson Disease","Healthy","GBA Gene Mutation",[77,79],"2025-02-27",{"date":83,"type":84},"2025-03-03","ACTUAL",{"date":86,"type":84},"2022-07-15",{"date":88,"type":73},"2025-07-15",{"name":5,"class":6},1]