[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100505195":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":17,"centralContacts":25,"locations":17,"responsibleParty":34,"collaborators":17,"id":36,"slug":37,"hasResults":38,"nctId":39,"briefTitle":40,"officialTitle":41,"acronym":17,"eligibilityCriteria":42,"healthyVolunteers":38,"sex":43,"minAge":44,"maxAge":45,"enrollmentInfo":46,"targetDuration":17,"studyType":49,"phases":50,"briefSummary":52,"conditions":53,"keywords":17,"overallStatus":55,"whyStopped":17,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":17},{"fullName":5,"class":6},"Peking Union Medical College Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"DEB group","EXPERIMENTAL","paclitaxel-coated balloon (Orchid, Acotec Scientific Holdings Limited, Beijing, China)",[13],"Procedure: Parallel Assignment",{"label":15,"type":16,"description":17,"interventionNames":18},"POB group","PLACEBO_COMPARATOR",null,[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":17},"PROCEDURE","Parallel Assignment","intervention group: treated with drug eluting balloon（paclitaxel-coated balloon； Orchid, Acotec Scientific Holdings Limited, Beijing, China)； control group :treated with plain old balloon",[9,15],[26,31],{"name":27,"role":28,"phone":29,"phoneExt":17,"email":30},"xitao song, MD","CONTACT","96-10-69152501","sxitao@sina.com",{"name":32,"role":28,"phone":33,"phoneExt":17,"email":17},"yuexin chen, MD","96-10-69152502",{"type":35,"investigatorFullName":17,"investigatorTitle":17,"investigatorAffiliation":17,"oldNameTitle":17,"oldOrganization":17},"SPONSOR","100505195","drug-eluting-balloon-for-treatment-of-non-atherosclerotic-renal-artery-stenosis--a-multicenter-study-100505195",false,"NCT05858190","Drug-eluting Balloon for Treatment of Non-atherosclerotic Renal Artery Stenosis--a Multicenter Study","Comparison of Drug Eluting Balloon and Plain Old Balloon for the Treatment of Non-atherosclerotic Renal Artery Stenosis--A Protocol of a Multicenter Study","Inclusion Criteria:\n\n* age between 18y and 45y.\n* with ≥ 60% stenosis in at least one renal artery.\n* with hypertension (systolic blood pressure ≥140 mmHg or diastolic blood pressure ≥ 90 mmHg).\n* patients with no severe renal insufficiency (eGFR\\>30 ml\u002Fmin, length of the kidney ≥ 7cm).\n* Good compliance.\n* with informed consent.\n\nExclusion Criteria:\n\n* With apparent atherosclerotic risk factors.\n* With renal intervention or surgery history.\n* With congenital anatomical anomaly.\n* With severe renal insufficiency (length of the target kidney \\\u003C 7cm, total\n* eGFR\\\u003C30ml\u002Fmin, divided eGFR of the target kidney\\\u003C8 ml\u002Fmin)\n* With contraindication for antiplatelet therapy.\n* With severe cardiopulmonary insufficiency.\n* Allergic to contrast medium\n* Being pregnant or preparing for pregnancy\n* With active cancer.\n* Life expectancy \\\u003C 12 month\n* Without informed consent","ALL","18 Years","45 Years",{"count":47,"type":48},90,"ESTIMATED","INTERVENTIONAL",[51],"NA","The study will test the efficacy of drug eluting balloon(DEB) for non-atherosclerotic renal artery stenosis. The DEB (paclitaxel eluting balloon) will be used in the intervention group, while the plain old balloon(POB) will be used in the control group. The primary outcome is the effect of blood pressure control.",[54],"Hypertension, Renovascular","NOT_YET_RECRUITING","2023-05-04",{"date":58,"type":59},"2023-05-15","ACTUAL",{"date":61,"type":48},"2023-06-01",{"date":63,"type":48},"2026-12-01",{"name":5,"class":6}]