[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100402586":3},{"organization":4,"armGroups":7,"interventions":16,"overallOfficials":32,"centralContacts":36,"locations":41,"responsibleParty":67,"collaborators":69,"id":75,"slug":76,"hasResults":77,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":81,"eligibilityCriteria":82,"healthyVolunteers":77,"sex":83,"minAge":84,"maxAge":85,"enrollmentInfo":86,"targetDuration":22,"studyType":89,"phases":90,"briefSummary":92,"conditions":93,"keywords":96,"overallStatus":60,"whyStopped":22,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},{"fullName":5,"class":6},"University Hospital, Lille","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental group","EXPERIMENTAL","All children born at the Lille University Hospital during the investigation period with esophageal atresia type III or IV",[13,14,15],"Device: Glycemic Holter","Radiation: gastric emptying scintigraphy","Device: Holter ECG",[17,23,28],{"type":18,"name":19,"description":20,"armGroupLabels":21,"otherNames":22},"DEVICE","Glycemic Holter","Continuous glycaemia monitoring,",[9],null,{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":22},"RADIATION","gastric emptying scintigraphy","Fasting administration of a Technecium-labelled milk bottle and quantification of the remaining radioactivity by a camera every 30 minutes for 4 hours.",[9],{"type":18,"name":29,"description":30,"armGroupLabels":31,"otherNames":22},"Holter ECG","continuous cardiac monitoring",[9],[33],{"name":34,"affiliation":5,"role":35},"Madelaine AUMAR, MD","PRINCIPAL_INVESTIGATOR",[37],{"name":34,"role":38,"phone":39,"phoneExt":22,"email":40},"CONTACT","0320445962","madeleine.aumar@chru-lille.fr",[42,58],{"facility":43,"status":44,"city":45,"state":22,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Hôpital Jeanne de Flandres","NOT_YET_RECRUITING","Lille","59037","France","FR",{"type":50,"coordinates":51},"Point",[52,53],3.05512,50.63391,{"lat":53,"lon":52},[56,57],{"name":22,"role":38,"phone":39,"phoneExt":22,"email":22},{"name":34,"role":35,"phone":22,"phoneExt":22,"email":22},{"facility":59,"status":60,"city":45,"state":22,"zip":22,"country":47,"countryCode":48,"cosmosGeoPoint":61,"geoPoint":63,"contacts":64},"Hôpital Jeanne de Flandre - Pôle enfant, CHU de Lille","RECRUITING",{"type":50,"coordinates":62},[52,53],{"lat":53,"lon":52},[65],{"name":66,"role":38,"phone":22,"phoneExt":22,"email":22},"Madeleine AUMAR",{"type":68,"investigatorFullName":22,"investigatorTitle":22,"investigatorAffiliation":22,"oldNameTitle":22,"oldOrganization":22},"SPONSOR",[70,72],{"name":71,"class":6},"Groupement Interrégional de Recherche Clinique et d'Innovation",{"name":73,"class":74},"french patient association for oesophageal atresia AFAO","UNKNOWN","100402586","dumping-syndrome-and-esophageal-atresia-100402586",false,"NCT04522193","Dumping Syndrome and Esophageal Atresia","Physiopathology of Dumping Syndrome in Esophageal Atresia","DUMTORING","Inclusion Criteria:\n\n* Patients operated at birth for Oesophageal atresia type C\n* Aged from 2 to 3 months at inclusion\n* Off prokinetic treatment (suspended for at least 72 hours) before monitoring\n\nExclusion Criteria:\n\n* History of dumping syndrome of other cause (microgastria, fundoplication, dysautonomia..)\n* History of any disease that can modify glycemic regulation (hyperinsulinism, neonatal diabete)\n* Treatment that can modify gastric motility","ALL","2 Months","3 Months",{"count":87,"type":88},15,"ESTIMATED","INTERVENTIONAL",[91],"NA","Dumping syndrome (DS) is frequent in oesophageal atresia (29%). In causing hypoglycaemia, it can be dangerous for neonates. Mechanisms of DS are actually partialy understood. This is also an affection difficult to diagnose, because it only occurs after meals and can be inconstantly present. To date, their is only symptomatic treatment for DS. This study aims to understand its pathological mechanisms so as to better treat it and avoid its consequences. Oesophageal atresia patients enrolled in this study will benefit from a continuous glycemic monitoring, a continuous cardiac monitoring, and an a gastric emptying scintigraphy at the age of 3 months",[94,95],"Oesophageal Atresia","Dumping Syndrome",[97,98,99,100],"Oesophageal dysmotility","Oesophageal atresia","Post prandial hypoglycaemia","Gastric emptying troubles","2025-12-17",{"date":103,"type":104},"2025-12-23","ACTUAL",{"date":106,"type":104},"2024-02-23",{"date":108,"type":88},"2026-11",{"name":5,"class":6},2]