[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100644979":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":26,"locations":34,"responsibleParty":65,"collaborators":68,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":73,"sex":79,"minAge":80,"maxAge":81,"enrollmentInfo":82,"targetDuration":20,"studyType":85,"phases":86,"briefSummary":88,"conditions":89,"keywords":92,"overallStatus":96,"whyStopped":20,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":106},{"fullName":5,"class":6},"Chinese University of Hong Kong","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Duodenal-jejunal bypass sleeve (DJBS)","EXPERIMENTAL","3 months implantation of DJBS",[13],"Procedure: Implantation of duodenal-jejunal bypass sleeve",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"PROCEDURE","Implantation of duodenal-jejunal bypass sleeve","The duodenal-jejunal bypass sleeve (DJBS) is a 60 cm thin, flexible tube. It is implanted into the duodenum using an endoscopy procedure and is kept in place for 3 months. After 3 months, it will be removed endoscopically.",[9],null,[22],{"name":23,"affiliation":24,"role":25},"Stephen Ng, FRCSEd","Prince of Wales Hospital, the Chinese University of Hong Kong","PRINCIPAL_INVESTIGATOR",[27,31],{"name":23,"role":28,"phone":29,"phoneExt":20,"email":30},"CONTACT","+85235052956","stephenng@surgery.cuhk.edu.hk",{"name":32,"role":28,"phone":20,"phoneExt":20,"email":33},"Ivy Study coordinator","ivypoon@surgery.cuhk.edu.hk",[35,54],{"facility":5,"status":20,"city":36,"state":20,"zip":20,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Shatin","Hong Kong","HK",{"type":40,"coordinates":41},"Point",[42,43],114.18333,22.38333,{"lat":43,"lon":42},[46,47,48,49,52],{"name":23,"role":28,"phone":29,"phoneExt":20,"email":30},{"name":32,"role":28,"phone":29,"phoneExt":20,"email":33},{"name":23,"role":25,"phone":20,"phoneExt":20,"email":20},{"name":50,"role":51,"phone":20,"phoneExt":20,"email":20},"Alice Kong, MD","SUB_INVESTIGATOR",{"name":53,"role":51,"phone":20,"phoneExt":20,"email":20},"Derek Xia, PhD",{"facility":55,"status":20,"city":36,"state":20,"zip":20,"country":37,"countryCode":38,"cosmosGeoPoint":56,"geoPoint":58,"contacts":59},"CUHK Medical Centre",{"type":40,"coordinates":57},[42,43],{"lat":43,"lon":42},[60,64],{"name":61,"role":28,"phone":62,"phoneExt":20,"email":63},"Simon Wong, FRCSEd","+85239466888","wongkhmo@cuhk.edu.hk",{"name":61,"role":51,"phone":20,"phoneExt":20,"email":20},{"type":25,"investigatorFullName":66,"investigatorTitle":67,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"Stephen KK Ng","Principal Investigator",[69],{"name":55,"class":70},"UNKNOWN","100644979","duodenal-jejunal-bypass-sleeve-djbs-for-obesity-and-metabolic-syndrome-100644979",false,"NCT07675122","Duodenal-jejunal Bypass Sleeve (DJBS) for Obesity and Metabolic Syndrome","Endoscopic Duodenal-jejunal Bypass Sleeve for Treatment of Obesity and Metabolic Syndrome - a Multicenter Pilot Study","DJBS-OMS","Inclusion Criteria:\n\n* Body mass index (BMI) ≥27.5kg\u002Fm2; or BMI ≥25 kg\u002Fm2 with metabolic syndrome\n\nExclusion Criteria:\n\n* Patients who have lost more than 5 kg of weight in the past three months\n* Patients who have used glucagon-like peptide-1 receptor agonists (GLP-1RAs) in the past three months\n* Patients who are currently taking weight loss drugs such as orlistat\n* Those who have taken antiplatelet drugs or anticoagulant drugs such as aspirin in the past month\n* iron deficiency or iron deficiency anemia\n* Gastrointestinal malformations, such as patients with gastrointestinal atresia or other patients who will cause gastrointestinal implantation failure\n* Those with a history of cholecystitis and liver abscess\n* There is a known infection, and the type of disease and the severity of the infection are not suitable for use by clinicians\n* coagulation dysfunction;\n* Severe liver and kidney dysfunction, AST \u002FALT \\> 2.5 times, total bilirubin \\> 35 μmol\u002FL, blood creatinine concentration greater than 180 μmol\u002FL\n* Patients with ASA IV \\& V\n* Drug or alcohol abuse addiction or suffering from uncontrollable mental illness\n* Duodenal bulb ulcer, gastric ulcer or previous and existing pancreatitis\n* Coronary heart disease, angina, cardiac function grade III or above, or pulmonary dysfunction\n* Patients who have undergone ERCP before\n* Patients with potential bleeding or telangiectasia in the stomach, esophagus, small intestine and other parts\n* Have a history of systemic lupus erythematosus, scleroderma\n* Those who have contraindications to endoscopy (judged by clinicians)\n* Pregnant women or those who are preparing to become pregnant\n* Those who are allergic to nickel-titanium\n* Any other situation that the clinician deems unsuitable for participation in this product","ALL","18 Years","65 Years",{"count":83,"type":84},20,"ESTIMATED","INTERVENTIONAL",[87],"NA","This study is designed to evaluate the efficacy, safety, and mechanisms of duodenal-jejunal bypass sleeve in patients with obesity",[90,91],"Obesity","Metabolic Syndrome (MetS)",[93,94,95],"duodenal-jejunal bypass sleeve","DJBS","DJBL","NOT_YET_RECRUITING","2026-06-25",{"date":99,"type":100},"2026-06-30","ACTUAL",{"date":102,"type":84},"2026-08-01",{"date":104,"type":84},"2029-07-31",{"name":5,"class":6},2]