[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100640178":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":45,"responsibleParty":61,"collaborators":26,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":70,"eligibilityCriteria":71,"healthyVolunteers":66,"sex":72,"minAge":26,"maxAge":73,"enrollmentInfo":74,"targetDuration":26,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":85,"overallStatus":48,"whyStopped":26,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Beni-Suef University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Dusting","EXPERIMENTAL","Participants will undergo transurethral Holmium:YAG laser cystolithotripsy using a dusting strategy with low pulse energy . The planned settings are 0.5-0.8 J and 10-15 Hz, aiming to reduce the bladder stone into fine particulate debris and tiny fragments with minimal need for active fragment extraction.",[13],"Procedure: Dusting Holmium:YAG Laser Cystolithotripsy",{"label":15,"type":16,"description":17,"interventionNames":18},"Fragmentation","ACTIVE_COMPARATOR","Participants will undergo transurethral Holmium:YAG laser cystolithotripsy using a fragmentation strategy with higher pulse energy. The planned settings are 1.0 J and 6-10 Hz, aiming to produce visible extractable stone fragments, approximately 2-5 mm, with active fragment removal when needed.",[19],"Procedure: Fragmentation Holmium:YAG Laser Cystolithotripsy",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Dusting Holmium:YAG Laser Cystolithotripsy","Transurethral Holmium:YAG laser cystolithotripsy using a dusting strategy with planned laser settings of 0.5-0.8 J and 10-15 Hz, aiming to reduce the bladder stone into fine particulate debris and tiny fragments with minimal need for active fragment extraction.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Fragmentation Holmium:YAG Laser Cystolithotripsy","Transurethral Holmium:YAG laser cystolithotripsy using a fragmentation strategy with planned laser settings of 1.0 J and 6-10 Hz, aiming to produce visible extractable stone fragments of approximately 2-5 mm, with active fragment removal when needed.",[15],[32],{"name":33,"affiliation":34,"role":35},"Hany F Badawy, MD","Faculty of Medicine, Beni-Suef University hospital","PRINCIPAL_INVESTIGATOR",[37,41],{"name":33,"role":38,"phone":39,"phoneExt":26,"email":40},"CONTACT","+201149525028","Hanyfathy86@gmail.com",{"name":42,"role":38,"phone":43,"phoneExt":26,"email":44},"Ghada S Etman, MD","+2010 07913852","DrhanYFATHY86@GMAIL.COM",[46],{"facility":47,"status":48,"city":49,"state":50,"zip":26,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"Department of Urology- Beni-Suef University Hospitals","RECRUITING","Banī Suwayf","Beni Suweif Governorate","Egypt","EG",{"type":54,"coordinates":55},"Point",[56,57],31.09785,29.07441,{"lat":57,"lon":56},[60],{"name":33,"role":38,"phone":39,"phoneExt":26,"email":40},{"type":35,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Hany Fathy Badawy, MD","Lecturer of Urology, Faculty of Medicine, Beni-Suef University","100640178","dusting-vs-fragmentation-laser-cystolithotripsy-for-pediatric-bladder-stones-100640178",false,"NCT07623980","Dusting vs Fragmentation Laser Cystolithotripsy for Pediatric Bladder Stones","Dusting Versus Fragmentation With Holmium:YAG Laser During Transurethral Cystolithotripsy in Pediatric Bladder Stones: A Prospective Randomized Trial","DUST-FRAG-PED","Inclusion Criteria:\n\n1. Children aged less than 18 years.\n2. Radiologically confirmed single bladder stone less than 3 cm.\n3. Suitable for transurethral cystolithotripsy.\n4. Fit for general anesthesia.\n5. Written informed consent from parents or legal guardians.\n\nExclusion Criteria:\n\n1. Giant bladder stones more than 3 cm.\n2. Urethral pathology preventing safe transurethral access.\n3. Major lower urinary tract anomaly or neurogenic bladder.\n4. Active untreated urinary tract infection.\n5. Coagulation disorder or contraindication to endoscopic surgery.","ALL","18 Years",{"count":75,"type":76},110,"ESTIMATED","INTERVENTIONAL",[79],"NA","Bladder stones are a clinically relevant pediatric urological condition that may require endoscopic treatment. Transurethral Holmium:YAG laser cystolithotripsy is a minimally invasive option for selected children with bladder stones.\n\nThis prospective randomized trial will compare two Holmium:YAG laser strategies during transurethral cystolithotripsy in children with a single bladder stone less than 3 cm: dusting and fragmentation. Children will be randomized to undergo laser dusting or laser fragmentation during transurethral cystolithotripsy.\n\nThe primary outcome is total operative time. Secondary outcomes include laser time, need for active fragment extraction, endoscopic stone-free status at the end of the procedure, ultrasound-assessed stone-free status during follow-up, intraoperative complications, postoperative urinary symptoms, urinary tract infection, need for postoperative catheterization, and hospital stay.",[82,83,84],"Bladder Calculi","Pediatric Bladder Stones","Pediatric Urolithiasis",[86,9,87,15,88],"Transurethral cystolithotripsy","Holmium:YAG laser","Bladder stone surgery","2026-05-28",{"date":91,"type":92},"2026-06-03","ACTUAL",{"date":94,"type":92},"2026-05-06",{"date":96,"type":76},"2027-05",{"name":5,"class":6},1]