[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100638066":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":27,"centralContacts":34,"locations":40,"responsibleParty":56,"collaborators":59,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":74,"sex":75,"minAge":76,"maxAge":10,"enrollmentInfo":77,"targetDuration":10,"studyType":80,"phases":10,"briefSummary":81,"conditions":82,"keywords":86,"overallStatus":90,"whyStopped":10,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"University of Alabama at Birmingham","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Group 1: Adults Using or Eligible for PrEP",null,"PrEP users - Individuals aged 18 years or older who are currently using or eligible for PrEP",[13],"Other: Observational cohort (PrEP use in real-world settings)",{"label":15,"type":10,"description":16,"interventionNames":17},"Group 2: PrEP Providers and Clinic Administrators","PrEP providers and clinic administrators - Individuals aged 18 years or older who work as PrEP providers or clinic administrators at outpatient clinics or inpatient settings",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Group 3: Policy Makers and Program Leaders","Policy makers and program leaders - Individuals aged 18 years or older who work as policy makers or program leaders at outpatient clinics or inpatient settings",[13],[23],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":10},"Observational cohort (PrEP use in real-world settings)","No intervention",[9,15,19],[28,31],{"name":29,"affiliation":5,"role":30},"Rena Patel, MD, MPH, MPhil","PRINCIPAL_INVESTIGATOR",{"name":32,"affiliation":33,"role":30},"Rebecca Zash","Division of Infectious Disease Beth Israel Deaconess Medical Center",[35],{"name":36,"role":37,"phone":38,"phoneExt":10,"email":39},"Rena Patel, MD, MPH","CONTACT","+12059348145","renapatel@uabmc.edu",[41],{"facility":42,"status":10,"city":43,"state":44,"zip":10,"country":45,"countryCode":46,"cosmosGeoPoint":10,"geoPoint":10,"contacts":47},"Princess Marina Hospital","Bontleng","Gaborone","Botswana","BW",[48,52],{"name":49,"role":37,"phone":50,"phoneExt":10,"email":51},"Chelsea Morroni, MBChB, DFSRH, DTMH, MPhil, MP","+267 765 24112","cmorroni@ed.ac.uk",{"name":53,"role":37,"phone":54,"phoneExt":10,"email":55},"Bame Bame","+267 72727347","bbame@bhp.org.bw",{"type":30,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Rena Patel","Principal Investigator",[60,63,65],{"name":61,"class":62},"National Institute of Allergy and Infectious Diseases (NIAID)","NIH",{"name":64,"class":6},"Beth Israel Deaconess Medical Center",{"name":66,"class":6},"Harvard School of Public Health (HSPH)","100638066","dynamic-decision-support-for-integrating-prep-in-clinics-for-young-people-in-alabama-and-botswana-100638066",false,"NCT07597824","DYnamic decisioN Support for IntegrAting PrEP in Clinics for Young People in Alabama and Botswana","DYNAMIC PrEP","Group 1\n\n* Inclusion for Alabama site:\n\n  * 18 years of age or older\n  * Currently using or eligible for PrEP\n* Inclusion for Botswana site:\n\n  * 18 years of age or older\n  * Participated in the parent Tshireletso study in Botswana\n* Exclusion for both sites:\n\n  * Under the age of 18\n  * HIV positive\n\nGroup 2\n\n* Inclusion for both sites:\n\n  * 18 years of age or older\n  * Currently working as PrEP providers or clinic administrators at outpatient clinics\n* Exclusion for both sites:\n\n  * Under the age of 18\n\nGroup 3\n\n* Inclusion for both sites:\n\n  * 18 years of age or older\n  * Currently working as policy makers or program leaders at outpatient clinics\n* Exclusion for both sites:\n\n  * Under the age of 18",true,"ALL","18 Years",{"count":78,"type":79},1000,"ESTIMATED","OBSERVATIONAL","This study evaluates strategies to improve access to HIV prevention through the integration of pre-exposure prophylaxis (PrEP) into existing healthcare settings, rather than limiting delivery to specialty clinics. The study addresses barriers to PrEP uptake, including limited awareness, stigma, and restricted access, and recognizes that availability alone may not ensure initiation or sustained use.\n\nThe study includes two components. First, a longitudinal cohort of current PrEP users will be followed to assess changes in access, preferences, and PrEP use over time in real-world settings. Second, a dynamic decision-support toolkit will be developed and evaluated to support patients and providers in PrEP-related decision-making. The toolkit will include patient- and provider-facing components to support clinical decision-making, improve risk understanding, and facilitate integration of PrEP into routine healthcare. The toolkit will be refined and beta-tested in selected healthcare facilities in Botswana and Alabama.",[83,84,85],"HIV Infections","Contraception","PrEP",[87,85,88,45,89],"HIV adherence","young adults","Alabama","NOT_YET_RECRUITING","2026-06-23",{"date":93,"type":94},"2026-06-25","ACTUAL",{"date":96,"type":79},"2026-06",{"date":98,"type":79},"2031-12",{"name":5,"class":6},1]