[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100554199":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":34,"responsibleParty":53,"collaborators":55,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":62,"acronym":10,"eligibilityCriteria":63,"healthyVolunteers":60,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":10,"studyType":70,"phases":10,"briefSummary":71,"conditions":72,"keywords":76,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Haukeland University Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Primary aldosteronism",null,"Patients with suspected and\u002For confirmed primary aldosteronism, aged 18-70 years",[13],"Device: dynamic microdialysis sampling",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DEVICE","dynamic microdialysis sampling","Included patients will perform 24-hour dynamic microdialysis sampling from subcutaneous tissue fluid of the lower abdomen, applying the U-Rhythm sampler. Simutaneous measurements of blood pressure, glucose, and registration of activity level, meals and sleep pattern during microdialysis sampling may be performed. Microdialysis sampling will be performed during various conditions: during daily life activities, during saline infusion suppression testing and during dexamethasone suppression testing. Repeated sampling may be performed post treatment.",[9],[21],{"name":22,"affiliation":5,"role":23},"Marianne Aarda Grytaas, MD PhD","PRINCIPAL_INVESTIGATOR",[25,30],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"Marianne Aardal Grytaas, MD PhD","CONTACT","004741545435","marianne.grytaas@helse-bergen.no",{"name":31,"role":27,"phone":32,"phoneExt":10,"email":33},"Kristian Løvås, MD PhD","004791113955","kristian.lovas@helse-bergen.no",[35],{"facility":5,"status":36,"city":37,"state":10,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"RECRUITING","Bergen","5021","Norway","NO",{"type":42,"coordinates":43},"Point",[44,45],5.32415,60.39299,{"lat":45,"lon":44},[48,51],{"name":49,"role":27,"phone":50,"phoneExt":10,"email":29},"Marianne Grytaas, MD phd","+4741545435",{"name":52,"role":27,"phone":10,"phoneExt":10,"email":33},"Kristian Løvås, MD Phd",{"type":54,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[56],{"name":57,"class":6},"University of Bergen","100554199","dynamic-hormone-profiling-and-multimodal-data-capture-in-primary-aldosteronism-100554199",false,"NCT06495983","Dynamic Hormone Profiling and Multimodal Data Capture in Primary Aldosteronism","Inclusion criteria Age 18 to 70 years Suspected PA admitted for diagnostic saline infusion testing or confirmed PA diagnosis according to Endocrine Society criteria.. Written informed consent\n\nExclusion criteria\n\n* Age \\\u003C18 or \\> 70 years.\n* Pregnancy.\n* Known adrenal failure and\u002For on steroid therapy (oral, inhaled, parenteral or topical) or other interfering medication.","ALL","18 Years","70 Years",{"count":68,"type":69},80,"ESTIMATED","OBSERVATIONAL","This study is a observational study applying 24-hour microdialysis methodology to perform dynamic multisteroid adrenal hormone profiling of patients with suspected or confirmed PA. Simultaneous registration of blood pressure, tissue glucose, sleep pattern, activity level and food intake registration may be performed. The overall objective is to develop a novel, sensitive, fast and user-friendly diagnostic procedure for PA, using multimodal data capture including dynamic multisteroid hormone profiling from microdialysis fluid.",[73,74,75],"Mineralocorticoid Excess","Primary Aldosteronism","Hypercortisolism",[77],"aldosterone","2024-07-03",{"date":80,"type":81},"2024-07-11","ACTUAL",{"date":83,"type":81},"2024-06-01",{"date":85,"type":69},"2028-12",{"name":5,"class":6},1]