[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100340769":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":25,"locations":34,"responsibleParty":53,"collaborators":56,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":10,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":10,"studyType":74,"phases":10,"briefSummary":75,"conditions":76,"keywords":78,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"The Hong Kong Polytechnic University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Pressure monitoring system for AIS",null,"Adolescent idiopathic scoliosis (AIS) patients\n\n(1) all target subjects are aged 10 to 15 years old with immature skeletons (Risser grade 0-2); (2) they are diagnosed with AIS with a Cobb angle between 25-45° and high risk for curve progression; (3) the types of scoliosis are classified by the Lenke classification system; and (4) the subjects have received rigid brace treatment.",[13],"Other: Pressure monitoring system",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"Pressure monitoring system","The pressure measurement undergarment will be given to all consenting AIS patients who have received their own thoraco-lumbo-sacral orthosis (TLSO) rigid brace. Each patient will wear the undergarment first and the TLSO brace on top. FBG sensors embedded in the undergarment will measure each pressure signal at approximately 2 minutes. The average force reading will be calculated.\n\nThen, the experiment will be repeated once, but the anisotropic textile brace will replace the TLSO brace. The pressure measurement system will be used to obtain an accurate and adequate comparison of the forces applied to the patients. The effectiveness of the anisotropic textile brace will be evaluated through X-ray radiography, and its correction effect with be compared with that of the TLSO brace.",[9],[20],"Pressure measurement undergarment",[22],{"name":23,"affiliation":5,"role":24},"Joanne Yip, PhD","PRINCIPAL_INVESTIGATOR",[26,30],{"name":23,"role":27,"phone":28,"phoneExt":10,"email":29},"CONTACT","852-27664848","joanne.yip@polyu.edu.hk",{"name":31,"role":27,"phone":32,"phoneExt":10,"email":33},"Kit Yick, PhD","852-27666551","tcyick@polyu.edu.hk",[35],{"facility":5,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"RECRUITING","Tsim Sha Tsui","Kolwoon","00852","Hong Kong","HK",{"type":43,"coordinates":44},"Point",[45,46],114.16667,22.3,{"lat":46,"lon":45},[49,51],{"name":23,"role":27,"phone":50,"phoneExt":10,"email":29},"85227664848",{"name":31,"role":27,"phone":52,"phoneExt":10,"email":33},"85227666551",{"type":24,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Joanne Yip","Professor",[57,59],{"name":58,"class":6},"Washington University School of Medicine",{"name":60,"class":6},"The University of Hong Kong","100340769","dynamic-pressure-monitoring-system-for-orthotic-treatment-of-scoliosis-100340769",false,"NCT03716843","Dynamic Pressure Monitoring System for Orthotic Treatment of Scoliosis","Design of a Dynamic Pressure Monitoring System for Orthotic Treatment of Scoliosis","Inclusion Criteria:\n\n* Teenagers diagnosed with adolescent idiopathic scoliosis\n* Cobb's angle between 25 to 45 degrees\n* Immature skeletons (Risser grade 0-2)\n* Types of scoliosis are classified by the Lenke classification system\n* Have received rigid brace treatment\n\nExclusion Criteria:\n\n* Contraindications for x-ray exposure\n* Diagnosis of other musculoskeletal or developmental illness that might be responsible for the spinal curvature\n* History of previous surgical treatment for AIS\n* Contraindications for pulmonary and\u002F or exercise tests\n* Psychiatric disorders\n* Recent trauma\n* Recent traumatic (emotional) event","ALL","10 Years","15 Years",{"count":72,"type":73},20,"ESTIMATED","OBSERVATIONAL","Adolescent idiopathic scoliosis (AIS) involves three-dimensional spinal deformity in children aged between 10 and 16. Traditional braces modify the natural dynamics and thus the mechanical behaviour of the scoliotic spine through external constraints. Patients usually develop pressure ulcers and skin irritation when prescribed brace treatment for 18-23 hours per day. The excessive pressure, unknown pressure distribution and pressure shifting between the human body and the brace causes the effects of brace treatment to be unpredictable. Dynamic pressure monitoring system will be developed based on the body landmarks of scoliotic patients and critical areas where active pressure is applied by the brace. The overall pressure distribution and dynamic pressure between the body and the thoraco-lumbo-sacral orthosis (TLSO) rigid brace will be measured. The efficacy of the brace design will be evaluated, and the maximum compressive stresses that patients can endure on different body parts without pressure injury can be computed.",[77],"Adolescent Idiopathic Scoliosis",[79],"Dynamic Pressure Monitoring","2024-10-16",{"date":82,"type":83},"2024-10-18","ACTUAL",{"date":85,"type":83},"2022-01-02",{"date":87,"type":73},"2027-12-31",{"name":5,"class":6},1]