[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100632634":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":7,"locations":13,"responsibleParty":30,"collaborators":7,"id":34,"slug":35,"hasResults":36,"nctId":37,"briefTitle":38,"officialTitle":39,"acronym":7,"eligibilityCriteria":40,"healthyVolunteers":36,"sex":41,"minAge":42,"maxAge":7,"enrollmentInfo":43,"targetDuration":7,"studyType":46,"phases":7,"briefSummary":47,"conditions":48,"keywords":50,"overallStatus":55,"whyStopped":7,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":65},{"fullName":5,"class":6},"Menoufia University","OTHER",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"DEVICE","Measuring dynamic central venous oxygen saturation (ScvO2) at baseline and after fluid challenge. Measuring Cardiac output by echocardiography or cardiometry at baseline and after fluid challenge.","We will correlate the changes in measuring cardiac output by both echocardiography and cardiometry with the changes in dynamic central venous oxygen saturation both at baseline and after fluid challenge to investigate the efficacy of dynamic central venous oxygen saturation in predicting fluid responsiveness in septic shock.",[14],{"facility":5,"status":7,"city":15,"state":7,"zip":7,"country":16,"countryCode":17,"cosmosGeoPoint":18,"geoPoint":23,"contacts":24},"Menouf","Egypt","EG",{"type":19,"coordinates":20},"Point",[21,22],30.93199,30.46597,{"lat":22,"lon":21},[25],{"name":26,"role":27,"phone":28,"phoneExt":7,"email":29},"Menoufia U MenoufiaU","CONTACT","01128861471","mostafanevine@gmail.com",{"type":31,"investigatorFullName":32,"investigatorTitle":33,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Nevine Mostafa Soliman","Assistant Professor","100632634","dynamic-svo2-in-predicting-fluid-responsiveness-in-septic-shock-100632634",false,"NCT07516236","Dynamic SvO2 in Predicting Fluid Responsiveness in Septic Shock","Diagnostic Accuracy of Dynamic Central Venous Oxygen Saturation in Predicting Fluid Responsiveness in Septic Shock: A Prospective Observational Study","Inclusion Criteria:\n\n* Age \\> 18 years\n* Diagnosis of septic shock according to Sepsis-3 criteria:\n\nSuspected or confirmed infection o Requirement for vasopressors to maintain MAP \\> 65 mmHg o Serum lactate \\> 2 mmol\u002FL despite adequate fluid resuscitation\n\nExclusion Criteria:\n\n* Pregnancy\n* Significant valvular heart disease.\n* Atrial fibrillation.\n* Inadequate echocardiographic window.\n* Ongoing bleeding or contraindication to fluid bolus.","ALL","18 Years",{"count":44,"type":45},115,"ESTIMATED","OBSERVATIONAL","This prospective observational diagnostic accuracy study investigates the efficacy of dynamic central venous oxygen saturation in predicting fluid responsiveness in septic shock, compared to measurements obtained using echocardiography (VTI) and cardiometry. We will correlate the changes in measuring cardiac output by both echocardiography and cardiometry with the changes in dynamic central venous oxygen saturation both at baseline and after fluid challenge to investigate the efficacy of dynamic central venous oxygen saturation in predicting fluid responsiveness in septic shock.",[49],"Sepsis and Septic Shock",[51,52,53,54],"Diagnostic Accuracy","Dynamic Venous Oxygen Saturation","Fluid Responsiveness","Septic Shock","NOT_YET_RECRUITING","2026-04-02",{"date":58,"type":59},"2026-04-07","ACTUAL",{"date":61,"type":45},"2026-04-01",{"date":63,"type":45},"2027-02-01",{"name":5,"class":6},1]