[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100430633":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":12,"locations":22,"responsibleParty":38,"collaborators":7,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":7,"eligibilityCriteria":48,"healthyVolunteers":44,"sex":49,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":7,"studyType":55,"phases":7,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":24,"whyStopped":7,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},{"fullName":5,"class":6},"University Hospital Hradec Kralove","OTHER",null,[9],{"name":10,"affiliation":5,"role":11},"Vladimir Palicka, MD, CSc.","STUDY_CHAIR",[13,18],{"name":14,"role":15,"phone":16,"phoneExt":7,"email":17},"Pavel Dostál, MD, PhD","CONTACT","+420602455632","pavel.dostal@fnhk.cz",{"name":19,"role":15,"phone":20,"phoneExt":7,"email":21},"Vladimir Koblizek, MD, Ph.D.","+420723448641","vladimir.koblizek@fnhk.cz",[23],{"facility":5,"status":24,"city":25,"state":7,"zip":26,"country":27,"countryCode":7,"cosmosGeoPoint":28,"geoPoint":33,"contacts":34},"RECRUITING","Hradec Králové","50005","Czechia",{"type":29,"coordinates":30},"Point",[31,32],15.83277,50.20923,{"lat":32,"lon":31},[35],{"name":36,"role":15,"phone":37,"phoneExt":7,"email":17},"Pavel Dostal, MD, PhD","00420495832266",{"type":39,"investigatorFullName":40,"investigatorTitle":41,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Dostalova Vlasta, MD, PhD","principal investigator","100430633","dynamics-of-markers-of-infection-and-inflammation-in-hospitalized-coronavirus-disease-2019-covid-19-patients-100430633",false,"NCT04887623","Dynamics of Markers of Infection and Inflammation in Hospitalized Coronavirus Disease 2019 (COVID-19) Patients","Dynamics of Nucleocapsid Antigen Serum Levels and Other Markers of Infection and Inflammation in Hospitalized Coronavirus Disease 2019 (COVID-19) Patients - a Pilot Study","Inclusion Criteria:\n\n* SARS CoV2 positive test within last 14 day\n* bilateral infiltrates on chest X.ray or CT\n* need for oxygen to keep pulse oximetry saturation above 92% or other respiratory support measures (HFNO, non-invasive ventilation or invasive ventilation)\n\nExclusion Criteria:\n\n* known history of intersticial lung disease\n* known history of congestive heart failure","ALL","18 Years","90 Years",{"count":53,"type":54},30,"ESTIMATED","OBSERVATIONAL","Patients requiring admission to the hospital due to a moderate and severe COVID-19 infection may differ in their ability to respond to viral infection and to eliminate viral load.\n\nSeveral comorbidities and interventions like antivirotic or antiinflammatory treatment may also modify expected patients response and decrease of viral load.\n\nIn this observational study, evolution of selected inflammatory markers, indicators of severity of infection and patient characteristics will be followed and recorded in hospitalized patients with COVID-19.",[58],"COVID-19 Respiratory Infection",[60,61,62,63],"Covid19","Interleukin 6","viremia","nucleocapsid antigen","2024-05-09",{"date":66,"type":67},"2024-05-10","ACTUAL",{"date":69,"type":67},"2021-04-01",{"date":71,"type":54},"2026-08",{"name":5,"class":6},1]