[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100583485":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":28,"locations":36,"responsibleParty":51,"collaborators":18,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":60,"eligibilityCriteria":61,"healthyVolunteers":62,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":18,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":77,"overallStatus":39,"whyStopped":18,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Arizona State University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Daily Avocado","EXPERIMENTAL","Infants in the daily avocado group will receive a daily exposure amount of avocado ranging from 1\u002F4 (\\~37.5 g or 1.25 oz) to 1\u002F2 (\\~75 g or 2.5 oz) of a medium-sized avocado.",[13],"Other: Daily avocado",{"label":15,"type":16,"description":17,"interventionNames":18},"No Avocado Control","NO_INTERVENTION","Infants in the control group will be asked to limit avocado exposure to no more than 1\u002F8 of a medium-sized avocado (\\~19 g, 2 Tbs) once per week.",null,[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":18},"Daily avocado","Infants in the daily avocado group will receive a daily exposure amount of avocado ranging from 1\u002F4 (\\~37.5 g or 1.25 oz) to 1\u002F2 (\\~75 g or 2.5 oz) of a medium-sized avocado. At 6-8 months, infants will be provided 1\u002F4 (\\~37.5 g or 1.25 oz) of a medium-sized avocado for daily consumption. Then from 9-12 months, they will begin receiving 1\u002F2 (\\~75 g or 2.5 oz) of a medium-sized avocado for daily consumption.",[9],[25],{"name":26,"affiliation":5,"role":27},"Corrie M Whisner, PhD","PRINCIPAL_INVESTIGATOR",[29,33],{"name":26,"role":30,"phone":31,"phoneExt":18,"email":32},"CONTACT","602-496-3348","cwhisner@asu.edu",{"name":34,"role":30,"phone":18,"phoneExt":18,"email":35},"Rachel Tribby, BS","rtribby@asu.edu",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":18},"College of Health Solutions","RECRUITING","Phoenix","Arizona","85004","United States","US",{"type":46,"coordinates":47},"Point",[48,49],-112.07404,33.44838,{"lat":49,"lon":48},{"type":27,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Corrie Whisner","Associate Professor","100583485","early-avocado-exposure-on-development-and-the-gut-microbiome-in-american-hispanic-infants-100583485",false,"NCT06876935","Early Avocado Exposure on Development and the Gut Microbiome in American Hispanic Infants","Guac & Grow: Early Avocado Exposure on Development and the Gut Microbiome in American Hispanic Infants","Guac & Grow","Inclusion Criteria:\n\n* 4-6-month-old Hispanic\u002FLatine, non-preterm (\\>37 weeks gestation) singleton infants\n* Infants born to mothers 18 years and older while pregnant\n* Parents speak English and\u002For Spanish\n* Families willing to begin feeding infants avocado around 6 months of age or when the infant is ready for solids for a total of 6 months\n* Family history of food or latex allergies will be evaluated as avocado is a latex fruit and can cause allergic responses. If either mom or dad is allergic to avocado, physician clearance for infant participation will be needed.\n* At least one caregiver in the home must have at least an 8th-grade education level\n\nExclusion Criteria:\n\n* Infants with growth, chromosomal, or genetic abnormality, developmental and cognitive impairments, or severe comorbidity that could impact growth and development\n* Infants born with congenital abnormalities or developmental delays\n* Infant birth weights \\\u003C2500 g or \\>4000 g\n* Infants introduced to solid foods prior to 3 months of age\n* Biological mothers with known substance use during pregnancy (alcohol, tobacco, marijuana, or illegal drugs), or who experienced a high-risk pregnancy (e.g., preeclampsia, diabetes-Types 1 and 2 and gestational, HIV, etc.)",true,"ALL","3 Months","6 Months",{"count":67,"type":68},150,"ESTIMATED","INTERVENTIONAL",[71],"NA","The goal of this clinical trial is to learn if daily avocado intake can improve growth and brain and gut health in infants. The main questions it aims to answer are:\n\nDoes daily eating of avocados change which microbes live in the infant's gut? Does daily avocado intake improve infant motor skills and cognitive development?\n\nResearchers will compare avocado intake to standard of care (no or limited avocado intake) to see if regular avocado intake from 6-12 months of life influences gut and brain health.\n\nParticipating mothers\u002Fguardians and their infants will:\n\nParents will provide avocado or no avocado to their infant every day for 6 months starting around 6 months of infant age.\n\nParents will allow study staff to visit participant homes to collect data via surveys and observations and measure infant growth.\n\nParents will swab soiled infant diapers for gut microbe measures. Parents will keep a diary of the infant's avocado consumption and acceptance of the food.\n\nParents will record their infant's dietary intake",[74,75,76],"Gut Microbiome","Neurocognitive Correlates of Eating Habits","Infant Growth",[78,79,80,81,82,83,84,85],"avocado","infants","complimentary feeding","growth","development","gut microbiome","neurocognitive","brain health","2025-08-21",{"date":88,"type":89},"2025-08-27","ACTUAL",{"date":91,"type":89},"2025-08-05",{"date":93,"type":68},"2027-12-31",{"name":5,"class":6},1]