[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100641778":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":18,"centralContacts":23,"locations":29,"responsibleParty":49,"collaborators":10,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":10,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":10,"enrollmentInfo":61,"targetDuration":64,"studyType":65,"phases":10,"briefSummary":66,"conditions":67,"keywords":70,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Odense University Hospital","OTHER",[8,12,15],{"label":9,"type":10,"description":11,"interventionNames":10},"Total Hip Arthroplasty",null,"Patients aged 70 years or older undergoing elective unilateral total hip arthroplasty with planned discharge on the day of surgery.",{"label":13,"type":10,"description":14,"interventionNames":10},"Total Knee Arthroplasty","Patients aged 70 years or older undergoing elective unilateral total knee arthroplasty with planned discharge on the day of surgery.",{"label":16,"type":10,"description":17,"interventionNames":10},"Unicompartmental Knee Arthroplasty","Patients aged 70 years or older undergoing elective unilateral unicompartmental knee arthroplasty with planned discharge on the day of surgery.",[19],{"name":20,"affiliation":21,"role":22},"Martin Lindberg-Larsen, Professor","Head of Research \u002F Consultant Orthopaedic Surgeon at Odense University Hospital. Department of Clinical Research, University of Southern Denmark (SDU)","PRINCIPAL_INVESTIGATOR",[24],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"Abdullahi Abdirisak Hirsi, MD","CONTACT","+4553376575","abdullahi.abdirisak.hirsi2@rsyd.dk",[30],{"facility":31,"status":32,"city":33,"state":10,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Odense University Hospital, Svendborg Hospital","RECRUITING","Svendborg","5700","Denmark","DK",{"type":38,"coordinates":39},"Point",[40,41],10.60677,55.05982,{"lat":41,"lon":40},[44,45,48],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},{"name":20,"role":26,"phone":46,"phoneExt":10,"email":47},"+4551435711","martin.lindberg-larsen@rsyd.dk",{"name":25,"role":22,"phone":10,"phoneExt":10,"email":10},{"type":22,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Abdullahi Abdirisak Hirsi","Medical doctor","100641778","early-cognitive-changes-after-same-day-discharge-hip-and-knee-arthroplasty-100641778",false,"NCT07598552","Early Cognitive Changes After Same-day Discharge Hip and Knee Arthroplasty","Early Cognitive Changes in Patients Aged 70 Years or Older After Same-day Discharge Hip and Knee Arthroplasty: A Prospective Cohort Study","Inclusion Criteria:\n\n* Unilateral elective primary Total Hip Arthroplasty, Total Knee Arthroplasty, or Unicompartmental Knee\n* Native Danish speaker\n* Spinal anesthesia\n\nExclusion Criteria:\n\n* Inability or unwillingness to provide informed consent\n* Inability to comply with virtual study procedures or follow-up sessions, including because of visual or hearing impairment\n* Known dementia or other diagnosed cognitive disorders or Brief Assessment of Impaired Cognition (BASIC)≤20\n* Parkinson's disease or other neurological conditions causing functional impairment\n* History of alcohol abuse (≥35 units per week)\n* Daily use of anxiolytics or hypnotics\n* Not discharged on the day of surgery","ALL","70 Years",{"count":62,"type":63},48,"ESTIMATED","7 Days","OBSERVATIONAL","The goal of this observational study is to explore early cognitive changes in patients aged 70 years or older undergoing same-day discharge after hip or knee replacement surgery. The main question it aims to answer is:\n\nDoes patients experience cognitive changes in cognitive test performance from before surgery to the first day after surgery?\n\nParticipants will:\n\n* Complete a cognitive test battery virtually about 14 days before surgery, and on the first and seventh day after their operation.\n* Record pain levels and pain medicine use during the first week after surgery",[68,69,13,16],"Postoperative Cognitive Dysfunction (POCD)","Cognitive Change",[71,72,73,74,75,76,77,78,79,80,81],"Same-day discharge","Fast-track surgery","Hip arthroplasty","Knee arthroplasty","Unicompartmental knee arthroplasty","Cognitive function","SDMT","Stroop test","Verbal fluency","Older adults","recovery","2026-06-17",{"date":84,"type":85},"2026-06-22","ACTUAL",{"date":87,"type":85},"2026-05-18",{"date":89,"type":63},"2026-11-30",{"name":5,"class":6},1]