[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100511776":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":23,"locations":28,"responsibleParty":50,"collaborators":10,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":54,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":10,"studyType":66,"phases":10,"briefSummary":67,"conditions":68,"keywords":70,"overallStatus":31,"whyStopped":10,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Centre Hospitalier Universitaire de Nice","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with a minor or major neurocognitive disorder",null,"Every patient will receive one semi-automated phone call, during the call a series of cognitive tasks will be performed.\n\nEach task will be recorded in a secondary audio stream which records the participant responses to allow for deep speech analysis of performance on these tasks",[13],"Other: Series of cognitive tasks during a semi-automated call",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Series of cognitive tasks during a semi-automated call","Tasks:\n\n* Verbal learning recall (immediate) or Story Recall task (immediate)\n* Narrative Storytelling \u002Ffree speech\n* Verbal fluency task\n* Verbal learning recall (delayed) or Story Recall task (delayed)",[9],[20],{"name":21,"affiliation":5,"role":22},"Eric ETTORE, MD","PRINCIPAL_INVESTIGATOR",[24],{"name":21,"role":25,"phone":26,"phoneExt":10,"email":27},"CONTACT","04.92.03.47.70","ettore.e@chu-nice.fr",[29],{"facility":30,"status":31,"city":32,"state":10,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"CHU de Nice","RECRUITING","Nice","06100","France","FR",{"type":37,"coordinates":38},"Point",[39,40],7.26608,43.70313,{"lat":40,"lon":39},[43,45,47],{"name":44,"role":25,"phone":10,"phoneExt":10,"email":10},"Lemaire Justine",{"name":46,"role":25,"phone":10,"phoneExt":10,"email":10},"Foussat Valérie",{"name":48,"role":49,"phone":10,"phoneExt":10,"email":10},"Alexandra Konig","SUB_INVESTIGATOR",{"type":51,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100511776","early-detection-of-alzheimers-disease-and-affective-disorders-by-automated-voice-and-speech-analysis-plata-100511776",false,"NCT05943834","Early Detection of Alzheimer's Disease and Affective Disorders by Automated Voice and Speech Analysis (PLATA)","Early Detection of Alzheimer's Disease and Affective Disorders by Automated Voice and Speech Analysis","PLATA","Inclusion Criteria:\n\n* Age ≥ 50 years\n* Diagnosis relevant biomarker and neuropsychological data already available\n* Cognitively healthy to very mild dementia (CDR score max. 0.5)\n* Sufficient knowledge of the study language to understand study information, non opposition form,and questionnaires\n* Expression of non opposition\n\nExclusion Criteria:\n\n* Hearing problems\n* Patient protected by law, under guardianship or curator ship, or not able to participate in a clinical study according to the article L.1121-16 of the French Public Health Code","ALL","50 Years","100 Years",{"count":64,"type":65},100,"ESTIMATED","OBSERVATIONAL","PLATA aims to develop an algorithm to identify vocal biomarkers of Alzheimer's dementia.\n\nUsing data collected as part of routine care, speech patterns will be compared to known biomarkers of Alzheimer's disease, such as amyloid 1-42 and p-Tau in CSF (cerebrospinal fluid).\n\nIf biomarkers of speech can be identified in Alzheimer's disease, it is possible that patients and research participants will no longer need to undergo need to undergo the intensive and invasive baseline biomarker methods currently used, such as lumbar punctures and PET scans.",[69],"Neurocognitive Disorders",[71,72],"Alzheimer's disease","Mood disorder","2026-03-17",{"date":75,"type":76},"2026-03-19","ACTUAL",{"date":78,"type":76},"2023-07-13",{"date":80,"type":65},"2027-10-10",{"name":5,"class":6},1]