[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100316407":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":18,"centralContacts":23,"locations":29,"responsibleParty":50,"collaborators":53,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":27,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":27,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":76,"overallStatus":32,"whyStopped":27,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"University of Sao Paulo","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Treatment group","Early high-dose corticosteroid and immunosuppressive therapy",[12],"Drug: Early high-dose corticosteroid and immunosuppressive therapy",[14],{"type":15,"name":10,"description":10,"armGroupLabels":16,"otherNames":17},"DRUG",[9],[9],[19],{"name":20,"affiliation":21,"role":22},"Joyce H Yamamoto, MD","University of Sao Paulo School of Medicine Ophthalmology","PRINCIPAL_INVESTIGATOR",[24],{"name":20,"role":25,"phone":26,"phoneExt":27,"email":28},"CONTACT","55-11-99266-6474",null,"joycehy@uol.com.br",[30],{"facility":31,"status":32,"city":33,"state":33,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Hospital das Clinicas HCFMUSP, Faculdade de Medicina Universidade de Sao Paulo","RECRUITING","São Paulo","05403-000","Brazil","BR",{"type":38,"coordinates":39},"Point",[40,41],-46.63611,-23.5475,{"lat":41,"lon":40},[44,47],{"name":45,"role":25,"phone":46,"phoneExt":27,"email":28},"Joyce Yamamoto, MD","11992666474",{"name":48,"role":25,"phone":27,"phoneExt":27,"email":49},"Marcelo M Lavezzo, MD","mmlavezzo@gmail.com",{"type":22,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":27,"oldOrganization":27},"Joyce Hisae Yamamoto","Professor",[54],{"name":55,"class":56},"Fundação de Amparo à Pesquisa do Estado de São Paulo","OTHER_GOV","100316407","early-immunosuppressive-therapy-on-the-course-of-vogt-koyanagi-harada-disease-100316407",false,"NCT03399175","Early Immunosuppressive Therapy on the Course of Vogt-Koyanagi-Harada Disease","Influência de imunomodulação Precoce Influence of Early Immunosuppressive Therapy on the Course of Vogt-Koyanagi-Harada Disease: a Prospective Study","Inclusion criteria:\n\n\\- acute Vogt-Koyanagi-Harada disease\n\nExclusion criteria:\n\n* non collaborative patient\n* minimum one-year follow-up","ALL","10 Years","70 Years",{"count":68,"type":69},40,"ESTIMATED","INTERVENTIONAL",[72],"NA","This prospective study will include patients with Vogt-Koyanagi-Harada disease from disease onset, treated with early systemic high-dose corticosteroid and immunosuppressive therapy. Clinical and subclinical signs of disease activity added with electroretinogram exams, through predefined intervals, will be evaluated through a minimum 12-month follow-up.",[75],"Vogt Koyanagi Harada Disease",[77,78,79,80,81],"Vogt-Koyanagi-Harada disease","Immunosuppressive therapy","Indocyanine green angiography","Enhanced depth imaging optical coherence tomography","Electroretinogram","2026-05-01",{"date":84,"type":85},"2026-05-07","ACTUAL",{"date":87,"type":85},"2015-03-23",{"date":89,"type":69},"2028-12",{"name":5,"class":6},1]