[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100583107":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":28,"centralContacts":32,"locations":37,"responsibleParty":58,"collaborators":24,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":67,"eligibilityCriteria":68,"healthyVolunteers":63,"sex":69,"minAge":70,"maxAge":24,"enrollmentInfo":71,"targetDuration":24,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":80,"overallStatus":39,"whyStopped":24,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Beijing Anzhen Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"ECMO+IABP group","EXPERIMENTAL","Patients receive IABP for left ventricular unloading within 6 hours after VA-ECMO initiation.",[13],"Other: Early IABP use",{"label":15,"type":16,"description":17,"interventionNames":18},"ECMO group","ACTIVE_COMPARATOR","Patients do not receive mechanical unloading within 6 hours after VA-ECMO initiation.",[19],"Other: Conventional approach",[21,25],{"type":6,"name":22,"description":11,"armGroupLabels":23,"otherNames":24},"Early IABP use",[9],null,{"type":6,"name":26,"description":17,"armGroupLabels":27,"otherNames":24},"Conventional approach",[15],[29],{"name":30,"affiliation":5,"role":31},"Xiaotong Hou, MD, PhD","PRINCIPAL_INVESTIGATOR",[33],{"name":30,"role":34,"phone":35,"phoneExt":24,"email":36},"CONTACT","010-64456631","xt.hou@ccmu.edu.cn",[38],{"facility":5,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"RECRUITING","Beijing","Beijing Municipality","100029","China","CN",{"type":46,"coordinates":47},"Point",[48,49],116.39723,39.9075,{"lat":49,"lon":48},[52,56],{"name":53,"role":34,"phone":54,"phoneExt":24,"email":55},"Liangshan Wang, MD","86-13811363372","wangliangshanbam@sina.com",{"name":57,"role":31,"phone":24,"phoneExt":24,"email":24},"Xiaotong Hou Hou, MD, PhD",{"type":31,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Xiaotong Hou","Professor","100583107","early-intra-aortic-balloon-pump-use-after-venoarterial-extracorporeal-membrane-oxygenation-100583107",false,"NCT06872021","Early Intra-aortic Balloon Pump Use After Venoarterial Extracorporeal Membrane Oxygenation","Early Intra-aortic Balloon Pump Use After Venoarterial Extracorporeal Membrane Oxygenation: The EASE-ECMO Randomized Clinical Trial","EASE-ECMO","Inclusion Criteria:\n\n1. Age of ≥18\n2. Cardiogenic shock(defined as a systolic blood pressure of less than 90 mm Hg for more than 30 minutes or the initiation of catecholamines to maintain a systolic pressure of more than 90 mm Hg, an arterial lactate level of more than 3 mmol per liter, and signs of impaired organ perfusion)\n3. Successful implantation of VA-ECMO\n4. Informed consent\n\nExclusion Criteria:\n\n1. SCAI shock stage A or B\n2. Presence of moderate to severe aortic insufficiency or aortic dissection\n3. Severe peripheral vascular disease\n4. Post-cardiotomy cardiogenic shock(non-CABG procedure) or bridging to cardiac procedure(heart transplantation or LVAD).\n5. VA-ECMO for definite non-cardiac causes\n6. Isolated right ventricular failure\n7. V-A ECMO usage confined to the period during surgery or other interventions\n8. Ischemic mechanical complications(eg Ventricular septal defect, papillary muscle rupture)\n9. Extracorporeal cardiopulmonary resuscitation\n10. LVAD, Impella or IABP in situ.\n11. Severe bleeding\n12. Terminal malignancy\n13. Irreversible neurologic injury\n14. Pregnancy or lactation","ALL","18 Years",{"count":72,"type":73},358,"ESTIMATED","INTERVENTIONAL",[76],"NA","The goal of this multicenter, randomized trial is to compare early early left ventricular unloading by Intra-aortic Balloon Pump (IABP) versus conventional approach in patients with cardiogenic shock (CS) undergoing venoarterial extracorporeal membrane oxygenation (VA-ECMO). The main question it aims to answer is :\n\n• If left ventricular unloading by IABP as compared with the conventional approach will improve the outcomes in patients undergoing VA-ECMO.",[79],"ECMO",[79,81,82],"IABP","LV unloading","2026-03-22",{"date":85,"type":86},"2026-03-24","ACTUAL",{"date":83,"type":86},{"date":89,"type":73},"2028-12-01",{"name":5,"class":6},1]