[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100526343":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":25,"responsibleParty":36,"collaborators":25,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":25,"eligibilityCriteria":46,"healthyVolunteers":42,"sex":47,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":25,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":25,"overallStatus":60,"whyStopped":25,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":25},{"fullName":5,"class":6},"Fundación Santa Fe de Bogota","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Early arm","ACTIVE_COMPARATOR","Early multimodal therapy is characterized by a comprehensive set of therapeutic interventions executed by the physiotherapy, speech therapy, respiratory therapy, and occupational therapy teams precisely at the moment of study inclusion. This tailored approach ensures that patients receive a coordinated and multidisciplinary therapeutic regimen right from the outset of their participation in the study",[13],"Procedure: Early Multimodal Therapy",{"label":15,"type":10,"description":16,"interventionNames":17},"Late arm","While late multimodal therapy is characterized by the same type of maneuvers carried out by the same disciplinary team but initiated once indicated by the attending physician.",[18],"Procedure: Late Multimodal Therapy",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Early Multimodal Therapy","Early multimodal therapy is defined as the collection of therapeutic maneuvers performed by the physiotherapy, speech therapy, respiratory therapy, and occupational therapy team at the time of study inclusion.",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Late Multimodal Therapy","Late multimodal therapy is characterized by the same set of maneuvers carried out by the same disciplinary team, but it is initiated once indicated by the attending physician.",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Jorge Alvarado, MD","CONTACT","3017858459","jialvarados@unal.edu.co",{"type":37,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Jorge Iván Alvarado","Principal investigator","100526343","early-multimodal-therapy-and-mechanical-ventilation-100526343",false,"NCT06133504","Early Multimodal Therapy and Mechanical Ventilation","Association Between Early Multimodal Therapy and Mechanical Ventilation Days in the Intensive Care Unit at Fundación Santa Fe de Bogotá: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\nThe inclusion criteria are as follows:\n\nPatients hospitalized in the adult intensive care unit of the Fundación Santa Fe de Bogotá.\n\nRequirement of invasive mechanical ventilation through an endotracheal tube for a period exceeding 72 hours with an expected continuation of at least 24 hours.\n\nBarthel Index equal to or greater than 70\n\nExclusion Criteria:\n\n* Invasive mechanical ventilation through tracheostomy or a nasotracheal tube.\n* History of head and neck surgery at any time prior to ICU admission.\n* Patients directly admitted to the ICU due to cardiac arrest by any cause.\n* Airway burn.\n* Burns involving ≥ 50% of the body surface area.\n* Chronic obstructive pulmonary disease (these patients usually require prolonged mechanical ventilation due to the underlying respiratory dysfunction)\n* Patients referred from another institution.\n* Demyelinating diseases or neuromuscular junction disorders at ICU admission.\n* Patients requiring neuromuscular blockade.\n* Patients with a life expectancy of ≤180 days will be excluded based on their primary diagnosis (e.g., advanced cancer, end-stage heart failure), comorbidities, recent clinical course, medical judgment by the ICU team, and functional status as assessed by the Barthel index.\n* ICU readmissions.\n* Participation in other rehabilitation clinical trials.\n* Liver or kidney transplant.\n* Patients with an active cancer diagnosis undergoing oncological treatment (chemotherapy\u002Fsurgery) at the time of eligibil- ity assessment.","ALL","18 Years","100 Years",{"count":51,"type":52},74,"ESTIMATED","INTERVENTIONAL",[55],"NA","To assess the association between early multimodal therapy and the duration of invasive mechanical ventilation in the Intensive Care Unit at Fundación Santa Fe de Bogotá.",[58,59],"Critical Care","Critical Illness","NOT_YET_RECRUITING","2025-07-03",{"date":63,"type":64},"2025-07-09","ACTUAL",{"date":66,"type":52},"2025-07",{"date":68,"type":52},"2026-06",{"name":5,"class":6}]