[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100493518":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":13,"centralContacts":17,"locations":23,"responsibleParty":79,"collaborators":81,"id":88,"slug":89,"hasResults":90,"nctId":91,"briefTitle":92,"officialTitle":93,"acronym":7,"eligibilityCriteria":94,"healthyVolunteers":90,"sex":95,"minAge":96,"maxAge":97,"enrollmentInfo":98,"targetDuration":7,"studyType":101,"phases":7,"briefSummary":102,"conditions":103,"keywords":7,"overallStatus":26,"whyStopped":7,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":119},{"fullName":5,"class":6},"Lund University","OTHER",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"DIAGNOSTIC_TEST","Early neurological prognostication with biomarkers, EEG and CT","Biomarker samples collected at 12, 24, 48 and 72 h after randomisation, CT and EEG performed as early as possible after 24 h post randomisation in patients still unconscious (defined as not awake and able to follow verbal commands)",[14],{"name":15,"affiliation":5,"role":16},"Niklas Nielsen, MD, PhD","STUDY_CHAIR",[18],{"name":19,"role":20,"phone":21,"phoneExt":7,"email":22},"Marion Moseby-Knappe, MD, PhD","CONTACT","00464671000","marion.moseby_knappe@med.lu.se",[24,42,55,68],{"facility":25,"status":26,"city":27,"state":7,"zip":7,"country":28,"countryCode":29,"cosmosGeoPoint":30,"geoPoint":35,"contacts":36},"Helsinki Hospital","RECRUITING","Helsinki","Finland","FI",{"type":31,"coordinates":32},"Point",[33,34],24.93545,60.16952,{"lat":34,"lon":33},[37,39],{"name":38,"role":20,"phone":7,"phoneExt":7,"email":7},"Markus Skrifvars, Prof",{"name":40,"role":41,"phone":7,"phoneExt":7,"email":7},"Marjaana Tiainen, MD, PhD","SUB_INVESTIGATOR",{"facility":43,"status":26,"city":44,"state":7,"zip":7,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":51,"contacts":52},"Charité University Hospital","Berlin","Germany","DE",{"type":31,"coordinates":48},[49,50],13.41053,52.52437,{"lat":50,"lon":49},[53],{"name":54,"role":20,"phone":7,"phoneExt":7,"email":7},"Christoph Leithner, MD",{"facility":56,"status":26,"city":57,"state":7,"zip":7,"country":58,"countryCode":59,"cosmosGeoPoint":60,"geoPoint":64,"contacts":65},"Helsingborgs Hospital","Helsingborg","Sweden","SE",{"type":31,"coordinates":61},[62,63],12.69437,56.04673,{"lat":63,"lon":62},[66],{"name":67,"role":20,"phone":7,"phoneExt":7,"email":7},"Niklas Nielsen, Prof",{"facility":69,"status":26,"city":70,"state":7,"zip":7,"country":58,"countryCode":59,"cosmosGeoPoint":71,"geoPoint":75,"contacts":76},"Skane University Hospital","Lund",{"type":31,"coordinates":72},[73,74],13.19321,55.70584,{"lat":74,"lon":73},[77],{"name":78,"role":20,"phone":7,"phoneExt":7,"email":7},"Josef Dankiewicz, MD, PhD",{"type":80,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR",[82,83,85,86],{"name":56,"class":6},{"name":84,"class":6},"University of Helsinki",{"name":69,"class":6},{"name":87,"class":6},"Charite University, Berlin, Germany","100493518","early-neuroprognostication-after-ohca-100493518",false,"NCT05706194","Early Neuroprognostication After OHCA","Early Neurological Prognostication of Outcome After Out-of-hospital Cardiac arrest-a STEPCARE Prospective Substudy","Inclusion Criteria:\n\nAdult cardiac arrest patients with an out-of-hospital cardiac arrest of non-traumatic cause treated at hospitals recruiting patients to the STEPCARE neuroprognostication substudy. Other inclusion criteria include:\n\n* a minimum of 20 minutes without chest compressions\n* Unconsciousness defined as not being able to obey verbal commands (FOUR-score motor response of \\\u003C4) or being intubated and sedated because of agitation after sustained ROSC\n* Eligible for intensive care without restrictions or limitations\n* Inclusion within 4 hours of ROSC\n\nExclusion Criteria:\n\n* On ECMO prior to randomisation\n* Pregnancy\n* Suspected or confirmed intracranial hemorrhage\n* Previously randomised in the STEPCARE trial\n* Patients with limitations in level-of-care due to for example generalized malignancy","ALL","18 Years","100 Years",{"count":99,"type":100},1000,"ESTIMATED","OBSERVATIONAL","This is a prospective observational substudy of the STEPCARE trial ClinicalTrials.gov Identifier: NCT05564754) with the aim to examine whether prognostication of neurological outcome after cardiac arrest can be performed earlier than the 72 h time-point recommended by guidelines today.",[104,105,106,107,108,109],"Cardiac Arrest","Neurological Outcome","EEG","CT","Brain Injuries","Biomarkers","2024-03-20",{"date":112,"type":113},"2024-03-21","ACTUAL",{"date":115,"type":113},"2023-10-01",{"date":117,"type":100},"2029-07-31",{"name":5,"class":6},4]