[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100643380":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":24,"locations":30,"responsibleParty":47,"collaborators":18,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":58,"minAge":59,"maxAge":18,"enrollmentInfo":60,"targetDuration":18,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":70,"overallStatus":33,"whyStopped":18,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Egas Moniz - Cooperativa de Ensino Superior, CRL","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Neobone® (Biphasic Calcium Phosphate)","EXPERIMENTAL","After tooth extraction the socket will be grafted with Neobone® (Biphasic Calcium Phosphate)",[13],"Device: Neobone® (Biphasic Calcium Phosphate)",[15],{"type":16,"name":9,"description":11,"armGroupLabels":17,"otherNames":18},"DEVICE",[9],null,[20],{"name":21,"affiliation":22,"role":23},"João Botelho, PhD in Biomedical Sciences","Clinical Research Unit (CRU), Egas Moniz Center for Interdisciplinary Research (CiiEM), Egas Moniz School of Health & Science","STUDY_DIRECTOR",[25],{"name":26,"role":27,"phone":28,"phoneExt":18,"email":29},"Angel Lobito, Masters' in Dentistry","CONTACT","00351924347050","alobito@egasmoniz.edu.pt",[31],{"facility":32,"status":33,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Clinica Dentária Egas Moniz","RECRUITING","Caparica","Monte Da Caparica","2829-511","Portugal","PT",{"type":40,"coordinates":41},"Point",[42,43],-9.20032,38.66179,{"lat":43,"lon":42},[46],{"name":26,"role":27,"phone":28,"phoneExt":18,"email":29},{"type":48,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100643380","early-phase-1-assessment-of-the-impact-of-neobone-biphasic-calcium-phosphate-on-bone-volume-in-alveolar-ridge-preservation-after-tooth-extraction-100643380",false,"NCT07638358","Assessment of the Impact of Neobone® (Biphasic Calcium Phosphate) on Bone Volume in Alveolar Ridge Preservation After Tooth Extraction","Assessment of Safety and Performance of Neobone®: A Prospective Observational Study in the Field of Dentistry","BCPARPBV","Inclusion Criteria:\n\n* 18 years or older\n* Acceptance of informed consent\n* Type 1 or 2 extraction sockets (Elian et al. 2007)\n\nExclusion Criteria:\n\n* Presence of active infection or severe inflammation in the intervention zone\n* Relevant medical history that contraindicates implant surgery\n* Patients with poor oral hygiene (full-mouth plaque score and full-mouth bleeding score \\>15%) and lack of motivation\n* Uncontrolled diabetes (reported levels of glycated haemoglobin exceeding 7%)\n* Uncontrolled and \u002For untreated periodontal disease\n* Heavy smokers (more than 10 cigarettes per day)\n* Immunosuppression",true,"ALL","18 Years",{"count":61,"type":62},30,"ESTIMATED","INTERVENTIONAL",[65],"EARLY_PHASE1","The goal of this randomized clinical trial is to assess whether BCP (Biphasic Calcium Phosphate) improves alveolar ridge preservation (ARP) in patients who need tooth extraction. The main question it aims to answer is whether using BCP for alveolar ridge preservation has a positive effect on bone volume compared with natural healing.\n\nThe main questions it aims to answer are:\n\nDoes BCP improve ridge preservation compared with natural healing?\n\nResearchers will compare BCP grafted sockets to natural healing sockets to see if BCP better preserves ridge volume.\n\nParticipants will:\n\nHave a tooth indicated for extraction.\n\nBe assigned to either BCP or natural healing.\n\nUndergo CBCT (Cone Beam Computed Tomography) and intra-oral scanning after extraction and after six months of healing to measure horizontal and vertical resorption and bone density.",[68,69],"Tooth Extraction Site Healing","Alveolar Ridge Preservation",[69,71,72,73,74,75,76,77],"Biphasic Calcium Phosphate","Tooth Extraction","Volumetric Changes","Implant site development","Bone volume","Socket preservation","Ridge augmentation","2026-06-09",{"date":80,"type":81},"2026-06-11","ACTUAL",{"date":83,"type":81},"2025-12-01",{"date":85,"type":62},"2028-12",{"name":5,"class":6},1]