[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100621696":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":34,"locations":18,"responsibleParty":42,"collaborators":18,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":18,"eligibilityCriteria":51,"healthyVolunteers":47,"sex":52,"minAge":53,"maxAge":18,"enrollmentInfo":54,"targetDuration":18,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":67,"whyStopped":18,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":18},{"fullName":5,"class":6},"Chulalongkorn University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Additional using of dental operating microscope in the procedure","EXPERIMENTAL","using of dental operating microscope in the procedure to improve the quality of treatment",[13],"Device: Using dental operating microscope",{"label":15,"type":16,"description":17,"interventionNames":18},"Rountine pulpotomy","NO_INTERVENTION","Rountine pulpotomy procedure without addition using of dental operating microscope",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"DEVICE","Using dental operating microscope","Using dental operating microscope additional to the procedure",[9],[26,30],{"name":27,"affiliation":28,"role":29},"Sirawut Hiran-us, DDS, MSc, High Grad Dip, FRCDS","Faculty of Dentistry, Chulalongkorn University","STUDY_DIRECTOR",{"name":31,"affiliation":32,"role":33},"Choontawee Soponsakulkaew, DDS, Higher Grad Dip, FRCDS","Phaholpolpayuhasena Hospital","PRINCIPAL_INVESTIGATOR",[35,39],{"name":27,"role":36,"phone":37,"phoneExt":18,"email":38},"CONTACT","66 812055775","sirawut.h@chula.ac.th",{"name":31,"role":36,"phone":40,"phoneExt":18,"email":41},"66 982693303","choontaweeso@gmail.com",{"type":33,"investigatorFullName":43,"investigatorTitle":44,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Sirawut Hiran-us","Associate Professor","100621696","early-phase-1-comparison-of-postoperative-pain-after-pulpotomy-performed-with-versus-without-dental-operating-microscope-in-carious-mature-permanent-teeth-100621696",false,"NCT07373977","Comparison of Postoperative Pain After Pulpotomy Performed With Versus Without Dental Operating Microscope in Carious Mature Permanent Teeth","Comparison of Postoperative Pain After Pulpotomy Performed With Versus Without Dental Operating Microscope in Carious Mature Permanent Teeth : A Randomized Controlled Trial","Inclusion Criteria:\n\n* Healthy patients aged at least 18 years old with deep or extremely deep carious lesions in mature permanent teeth diagnose with symptomatic irreversible pulpitis. Diagnoses are confirmed using EPT and cold tests. Pulpal and periapical diagnoses are based on terminology from the American Association of Endodontists (AAE, 2013)20.\n* Posterior teeth with moderate or severe pain according to The NRS (Numeric Rating Scale) According to this scale, the level of pain is documented in the range of 0-10 numerically and verbally as no pain (0), mild pain, non-disruptive to routine activities (1-3), moderate pain that interferes with daily life but no need analgesics intake (4-6) and severe pain that significantly disrupts normal acitivities requiring analgesic intervention (7-10).\n* Teeth that response negatively to percussion and palpation tests.\n* Teeth are restorable with direct composite restoration.\n\nExclusion Criteria:\n\n* Teeth with subgingival caries and\u002For clinical attachment loss more than 3 mm and probing depth more than 4 mm.\n* Negative responses to pulp sensibility tests, presence of sinus tracts, swelling, non-restorable crowns, immature roots, or no pulp exposure following complete caries removal in case of pre-operative diagnosis as asymptomatic irreversible pulpitis.\n* Patients with systemic diseases involving bleeding disorders such as hemophilia, Von Willebrand disease, platelet disorders. And patients under taking all kind of anticoagulant and anti-platelet.\n* Patients who had taken analgesics or anti-inflammatory drugs within the previous 24 hours. If necessary, record how many and dose that taken.\n* Patients taking opioids.\n* Known allergies to non-steroidal anti-inflammatory drugs (NSAIDs).\n* Pregnant or lactating patients.\n* Teeth with pulpal obliteration.\n* Necrotic pulp is found after access opening\n* Bleed cannot be stopped within 8 minutes after full pulpotomy","ALL","18 Years",{"count":55,"type":56},82,"ESTIMATED","INTERVENTIONAL",[59],"EARLY_PHASE1","The goal of this \\[randomized clinical trials\\] is to investigate the effect of using dental operating microscope incorperated in full pulpotomy procedure in mature carious posterior teeth.\n\nThe main questions it aims to answer are:\n\ninvestigate postoperative pain levels.\n\ninvestigate the quality of life of patient after treatment.\n\nIf there is a comparison group: Researchers will compare the pulpotomy procedure with and without using dental operating microscope.\n\nParticipants will will be asked to do\n\n* Pain evaluation with numerical rating scale\n* OHIP 14 survey before and after treatment",[62],"Carious Exposure of Pulp",[64,65,66],"Pulpotomy","Dental operating microscope","post-operative pain","NOT_YET_RECRUITING","2026-01-28",{"date":70,"type":71},"2026-01-30","ACTUAL",{"date":73,"type":56},"2026-02-10",{"date":75,"type":56},"2026-12-31",{"name":5,"class":6}]