[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100644467":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":53,"collaborators":25,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":25,"eligibilityCriteria":63,"healthyVolunteers":64,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":25,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":78,"overallStatus":39,"whyStopped":25,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Mansoura University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"conventional non-surgical periodontal therapy","EXPERIMENTAL","conventional mechanical debridement",[13],"Device: Mechanical debridement .",{"label":15,"type":10,"description":16,"interventionNames":17},"Minimally Invasive Non-Surgical Therapy","the root surface of teeth will be thoroughly debrided by a minimally invasive approach using specific thin and delicate piezo-electric scaling tips (Woodpecker � Tip P3. Am Perfect sp. z o .• � Poland) and manual miniature periodontal curettes {� Dent Solutions. Cairo. Egypt) for reducing periodontal tissue trauma. Adjunctive use of magnification loupes will be performed.",[18],"Device: minimally invasive mechanical debridement",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Mechanical debridement .","On the conventional non-surgical periodontal therapy side, a power-driven piezo•electric ultrasonic scaling device with scaling tips will be used the majority of the time to debride subgingival biofilm and calculus. and manual standard gracey curette instruments will be used to refine residuals from root surfaces.",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"minimally invasive mechanical debridement","Briefly. the root surface of teeth will be thoroughly debrided by a minimally invasive approach using specific thin and delicate piezo-electric scaling tips (Woodpecker � Tip P3. Am Perfect sp. z o .• � Poland) and manual miniature periodontal curettes {� Dent Solutions. Cairo. Egypt) for reducing periodontal tissue trauma. Adjunctive use of magnification loupes will be performed.",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"fatma saad elsherbini, phd","CONTACT","+201128065677","elsherbinifatma@mans.edu.eg",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Mansoura university Faculty of dentistry","RECRUITING","Al Mansurah","Dakhlia","00000","Egypt","EG",{"type":46,"coordinates":47},"Point",[48,49],31.38069,31.03637,{"lat":49,"lon":48},[52],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},{"type":54,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Fatma saad saad mahmoud elsherbini","PhD, Lecturer, Oral Medicine, Periodontology, Diagnosis, and Oral Radiology Department,","100644467","early-phase-1-comparison-of-the-efficacy-of-conventional-versus-minimally-invasive-non-surgical-periodontal-therapy-in-periodontitis-patients-100644467",false,"NCT07671274","Comparison of the Efficacy of Conventional Versus Minimally Invasive Non-Surgical Periodontal Therapy in Periodontitis Patients","Comparison of the Efficacy of Conventional Versus Minimally Invasive Non-Surgical Periodontal Therapy in Periodontitis Patients (Randomized Controlled Clinical Trial)","Inclusion Criteria:\n\n* • Patients with stage III pericdontitis, according to the American Academy of Periodontology (AAP) and the European Federation of Periodontology (EFP) periodontal classification system .\n\n  * Medically free patients.\n  * Non-smokers\n  * Patients with good oral hygiene.\n\nExclusion Criteria:\n\n* Pregnant or lactating females.\n\n  * Patients with systemic diseases that might affect periodontal health\n  * previous periodontal treatment within 6 months before baseline examination.\n  * prior antibiotic regimen use within 1 month before baseline examination",true,"ALL","20 Years","40 Years",{"count":69,"type":70},30,"ESTIMATED","INTERVENTIONAL",[73],"EARLY_PHASE1","the aim of this study is to investigate the clinical outcomes of Minimally Invasive Non-Surgical Therapy(MINST) compared to Conventional non-surgical periodontal therapy (CNST)",[76,77],"Periodontal Disease","Stage III Periodontitis",[79,80,81],"periodontitis","stage III","mechanical debridement","2026-06-24",{"date":84,"type":85},"2026-06-26","ACTUAL",{"date":87,"type":85},"2025-08-05",{"date":89,"type":70},"2026-08-05",{"name":5,"class":6},1]