[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100555827":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":28,"locations":24,"responsibleParty":35,"collaborators":24,"id":39,"slug":40,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":24,"eligibilityCriteria":45,"healthyVolunteers":46,"sex":47,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":24,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":24,"overallStatus":59,"whyStopped":24,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":24},{"fullName":5,"class":6},"Brunel University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Rate of change in core temperature during CRYOGENX cooling","EXPERIMENTAL","Participants will visit the laboratory on three occasions during this randomized, counter-balanced crossover study. The first visit will enable preliminary data collection and familiarisation to take place. The second and third visits will be experimental sessions (CRYOGENX cooling vs regular cooling), with the order of these randomised. The rate of change in core temperature during cooling observed in the two trials will be compared by paired sample t-tests.",[13],"Device: Cryogenx cooling",{"label":15,"type":10,"description":11,"interventionNames":16},"Rate of change in core temperature during regular cooling",[17],"Device: Regular cooling",[19,25],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DEVICE","Cryogenx cooling","During the cooling phase of both trials established field based cooling approaches e.g., temperate temperature water spraying (30°C, 5 mL.min-1), and air circulation (electric fan 2 m distance, 1.7 m.s-1 will be implemented. During the CRYOGENX cooling trial, the product will be affixed to the participant's torso in accordance with manufacturer's instructions and they will receive cooling via this intervention in addition to water spraying and air circulation. During the control visit, no intervention will be applied however water spraying and air circulation will be received.",[9],null,{"type":20,"name":26,"description":22,"armGroupLabels":27,"otherNames":24},"Regular cooling",[15],[29],{"name":30,"role":31,"phone":32,"phoneExt":33,"email":34},"Oliver R Gibson, PhD","CONTACT","+44(0)1895 267957","7957","oliver.gibson@brunel.ac.uk",{"type":36,"investigatorFullName":37,"investigatorTitle":38,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Dr Oliver Gibson","Principal Investigator","100555827","early-phase-1-cooling-via-cryogenx-body-cooling-device-100555827",false,"NCT06517147","Cooling Via Cryogenx Body Cooling Device","Efficacy of Post Exercise Heat Stress Cooling Via Cyrogenx Body Cooling Device","The inclusion criteria are:\n\nAged 18 - 40 years Free from known injury, illness and disease and regular use of medications other than oral contraceptives Undertake exercise training \\>3 times per week for \\~30 minutes per session\n\nThe exclusion criteria are:\n\nPregnant Previous history of neuromuscular fatigue Previous history of heat intolerance",true,"ALL","18 Years","40 Years",{"count":51,"type":52},12,"ESTIMATED","INTERVENTIONAL",[55],"EARLY_PHASE1","The aim of this project is to test the rate of cooling following exercise in the heat utilising the CRYOGENX Cryosuit device i) against passive cooling, and ii) to quantify the rate of cooling and compare this rate with established cooling intervention thresholds i.e. -0.11 to 0.15°C.min-1. As this project is to determine the efficacy of the intervention in populations equivalent to sporting and military personnel, these aims will be tested in young (18-40 year old) healthy male and female participants whom participate in regular physical activity. As a commercially funded project, the experimental design implemented will closely replicate that of the independent investigation into the efficacy of the CAERvest® device.",[58],"Body Temperature Changes","NOT_YET_RECRUITING","2024-07-18",{"date":62,"type":63},"2024-07-24","ACTUAL",{"date":65,"type":52},"2024-09-01",{"date":67,"type":52},"2025-07-31",{"name":5,"class":6}]