[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100614594":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":45,"responsibleParty":68,"collaborators":26,"id":72,"slug":73,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":26,"eligibilityCriteria":78,"healthyVolunteers":74,"sex":79,"minAge":80,"maxAge":81,"enrollmentInfo":82,"targetDuration":26,"studyType":85,"phases":86,"briefSummary":88,"conditions":89,"keywords":91,"overallStatus":48,"whyStopped":26,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"Punjab Health Care Commission","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Decompressive Laminectomy Only","ACTIVE_COMPARATOR","Surgical decompressive laminectomy performed without instrumented fixation in patients with multilevel lumbar spinal stenosis.",[13,14],"Procedure: Decompressive Laminectomy","Procedure: Decompressive Laminectomy With Transpedicular Screw Fixation",{"label":16,"type":17,"description":18,"interventionNames":19},"Laminectomy With Transpedicular Screw Fixation","EXPERIMENTAL","Surgical decompressive laminectomy combined with transpedicular screw fixation to provide additional spinal stability in patients with multilevel lumbar spinal stenosis.",[13,14],[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Decompressive Laminectomy","Surgical removal of the vertebral lamina to decompress the spinal canal in patients with multilevel lumbar spinal stenosis. No instrumentation or fixation is applied.",[9,16],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Decompressive Laminectomy With Transpedicular Screw Fixation","Surgical decompression via laminectomy combined with spinal stabilization using transpedicular pedicle screws for multilevel lumbar spinal stenosis to prevent postoperative instability and provide bony fusion.",[9,16],[32],{"name":33,"affiliation":34,"role":35},"Hira Umar, MBBS","SIMS SIUT","PRINCIPAL_INVESTIGATOR",[37,41],{"name":33,"role":38,"phone":39,"phoneExt":26,"email":40},"CONTACT","+92 317 4226862","quickcareclinicdr03@gmail.com",{"name":42,"role":38,"phone":43,"phoneExt":26,"email":44},"Fazal Rehman, MBBS","03227793559","fazal171@gmail.com",[46],{"facility":47,"status":48,"city":49,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"Services Institute of Medical Sciences","RECRUITING","Lahore","Punjab Province","60000","Pakistan","PK",{"type":55,"coordinates":56},"Point",[57,58],74.35071,31.558,{"lat":58,"lon":57},[61,65],{"name":62,"role":38,"phone":63,"phoneExt":26,"email":64},"Burhan Amjad, MBBS","+92 300 5457200","info.health@punjab.gov.pk",{"name":66,"role":38,"phone":67,"phoneExt":26,"email":64},"Madiha Suleman, MBBS","03238092608",{"type":35,"investigatorFullName":69,"investigatorTitle":70,"investigatorAffiliation":71,"oldNameTitle":26,"oldOrganization":26},"Hira Umar","Doctor","Services Institute of Medical Sciences, Pakistan","100614594","early-phase-1-decompressive-laminectomy-versus-laminectomy-with-transpedicular-fixation-in-lumbar-spinal-stenosis-100614594",false,"NCT07281625","Decompressive Laminectomy Versus Laminectomy With Transpedicular Fixation in Lumbar Spinal Stenosis","A Randomized Controlled Trial Comparing Surgical Outcomes of Decompressive Laminectomy Versus Decompressive Laminectomy With Transpedicular Screw Fixation in Multilevel Lumbar Spinal Stenosis","Inclusion Criteria:\n\n* Age 30-60 years\n* Diagnosis of lumbar spinal stenosis based on MRI criteria (anteroposterior canal diameter \\\u003C10-15 mm or cross-sectional area \\\u003C75-145 mm²)\n* Multilevel disc herniation\n* Degenerative disc disease with Pfirrmann grade 3-5 on T2-weighted MRI\n* Failure of at least six weeks of conservative treatment\n\nExclusion Criteria:\n\n* Previous history of lumbar spine surgery\n* Spinal malignancy\n* Congenital lumbar spinal stenosis, scoliosis, or kyphoscoliosis\n* Lumbar spondylolisthesis grade 3-5\n* Significant comorbidities including diabetes mellitus or ischemic heart disease","ALL","30 Years","60 Years",{"count":83,"type":84},60,"ESTIMATED","INTERVENTIONAL",[87],"EARLY_PHASE1","Lumbar spinal stenosis is a condition where the spinal canal becomes narrowed and can cause symptoms such as back pain, numbness, leg pain, and difficulty walking. Surgery is often considered when symptoms do not improve with medical treatment.\n\nThis study will compare two types of surgery used to treat lumbar spinal stenosis: decompressive laminectomy alone and decompressive laminectomy with transpedicular screw fixation. Patients will be randomly assigned to one of the two surgical options.\n\nThe purpose of this study is to determine which approach provides better pain relief, improved function, fewer complications, and better spinal stability after surgery.",[90],"Lumbar Spinal Stenosis",[92,93,94,95],"laminectomy","spinal stenosis","lumbar fusion","VAS pain score","2025-12-02",{"date":98,"type":99},"2025-12-15","ACTUAL",{"date":101,"type":99},"2025-10-01",{"date":103,"type":84},"2025-12-31",{"name":5,"class":6},1]