[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100517355":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":33,"centralContacts":40,"locations":47,"responsibleParty":70,"collaborators":45,"id":72,"slug":73,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":45,"eligibilityCriteria":78,"healthyVolunteers":74,"sex":79,"minAge":80,"maxAge":81,"enrollmentInfo":82,"targetDuration":45,"studyType":85,"phases":86,"briefSummary":88,"conditions":89,"keywords":91,"overallStatus":50,"whyStopped":45,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"Texas Tech University Health Sciences Center, El Paso","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Dexamethasone","EXPERIMENTAL","single oral dose of dexamethasone (8mg)",[13],"Drug: Dexamethasone Oral",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR","Single oral dose of placebo pill",[19],"Drug: Placebo",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Dexamethasone Oral","Two 4mg pills",[9],[27],"Decadron",{"type":22,"name":15,"description":29,"armGroupLabels":30,"otherNames":31},"2 placebo pills",[15],[32],"Dextrose methyl cellulose",[34,38],{"name":35,"affiliation":36,"role":37},"Susan Watts, PhD.","Texas Tech University Health Sciences Center, Department of Emergency Medicine","STUDY_DIRECTOR",{"name":39,"affiliation":5,"role":37},"Diluma Kariyawasam, MPH",[41],{"name":42,"role":43,"phone":44,"phoneExt":45,"email":46},"Edward Michelson, MD","CONTACT","915 215 4600",null,"edward.michelson@ttuhsc.edu",[48],{"facility":49,"status":50,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"University Medical Center of El Paso","RECRUITING","El Paso","Texas","79905","United States","US",{"type":57,"coordinates":58},"Point",[59,60],-106.48693,31.75872,{"lat":60,"lon":59},[63,67],{"name":64,"role":43,"phone":65,"phoneExt":45,"email":66},"Leann Rodriguez","(915) 215-4976","rod72863@ttuhsc.edu",{"name":68,"role":69,"phone":45,"phoneExt":45,"email":45},"Edward A Michelson, MD","PRINCIPAL_INVESTIGATOR",{"type":69,"investigatorFullName":42,"investigatorTitle":71,"investigatorAffiliation":5,"oldNameTitle":45,"oldOrganization":45},"Professor and Chair Dept of Emergency Medicine","100517355","early-phase-1-does-nerve-block--oral-dexamethasone-reduce-recurrence-of-headache-within-72-hrs-100517355",false,"NCT06016465","Does Nerve Block + Oral Dexamethasone Reduce Recurrence of Headache Within 72 Hrs?","Does Nerve Block Plus Oral Dexamethasone Reduce Recurrence of Headache Within 72 Hours Better Than Nerve Block Alone?","Inclusion Criteria:\n\n* Meet ICHD-3 Migraine Headache Criteria\n* Had a minimum 5-point reduction in headache intensity after nerve block(s) or post- block pain score of 0 to 2\n* Nerve block performed with bupivacaine 0.5%\n\nExclusion Criteria:\n\n* Head trauma\n* Suspicion of secondary headache (i.e. stroke, known tumor, glaucoma)\n* Headache in the setting of viral syndrome\n* Chronically on steroids\n* Known allergy to dexamethasone\n* Unable to reach the patient by phone or text for follow-up\n* Gestational diabetes or other uncontrolled diabetes\n* Known to be immunocompromised","ALL","18 Years","85 Years",{"count":83,"type":84},84,"ESTIMATED","INTERVENTIONAL",[87],"EARLY_PHASE1","For some patients who come to the emergency department for treatment of a migraine headache, peripheral headache nerve blocks (PHNB) have proven to be an efficient and effective treatment for headache relief. Previous studies have demonstrated that adding steroids as an adjunct treatment to standard migraine treatment can reduce recurrence of headaches in the subsequent few days.",[90],"Migraine",[92,93,94,95],"migraine headache","peripheral nerve block","dexamethasone","steroid treatment","2026-04-30",{"date":98,"type":99},"2026-05-06","ACTUAL",{"date":101,"type":99},"2023-09-15",{"date":103,"type":84},"2028-01-30",{"name":5,"class":6},1]