[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100459550":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":25,"centralContacts":26,"locations":25,"responsibleParty":32,"collaborators":25,"id":36,"slug":37,"hasResults":38,"nctId":39,"briefTitle":40,"officialTitle":41,"acronym":25,"eligibilityCriteria":42,"healthyVolunteers":43,"sex":44,"minAge":45,"maxAge":46,"enrollmentInfo":47,"targetDuration":25,"studyType":50,"phases":51,"briefSummary":53,"conditions":54,"keywords":25,"overallStatus":56,"whyStopped":25,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":25},{"fullName":5,"class":6},"Sheikh Zayed Medical College","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Dexmedetomidine","EXPERIMENTAL","Inj.Dexmedetomidine(precidex ) 200mcg\u002F2ml Given to participants in infusion form for 24 hours",[13],"Drug: Dexmedetomidine Hydrochloride",{"label":15,"type":10,"description":16,"interventionNames":17},"Midazolam","Inj.midazolam 5mg\u002Fml given to participants in infusion form for 24 hrs",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DRUG","Dexmedetomidine Hydrochloride","Inj dexmedetomidine and inj midazolam given to two groups of participants and effects of both drugs will be observed for 24 hrs",[9,15],[15],null,[27],{"name":28,"role":29,"phone":30,"phoneExt":25,"email":31},"Momal j Khan","CONTACT","03116660901","momal.rehan56@gmail.com",{"type":33,"investigatorFullName":34,"investigatorTitle":35,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Momal Jaleel Khan","Dr.Momal jaleel khan","100459550","early-phase-1-efficacy-of-dexmedetomidine-vs-midazolam-for-early-extubation-in-critically-ill-agitated-patients-undergoing-weaning-100459550",false,"NCT05264077","Efficacy of Dexmedetomidine vs Midazolam for Early Extubation in Critically Ill Agitated Patients Undergoing Weaning","Efficacy of Dexmedetomidine Versus Midazolam for Early Extubation in Critically Ill Agitated Patients Undergoing Weaning","Inclusion Criteria:\n\n* all patients with age \\\u003C60 irrespective of gendre\n\nExclusion Criteria:\n\n\\- Patients who refuse to give consent, severely altered conscious level (GCS \\\u003C 8\u002F15), traumatic injury causing hypoxemia e.g., severe head \u002F chest \u002F facial trauma or pneumothorax, severe pneumonia, arrhythmia, impaired hearing or blindness, severe hepatic or renal disease, on neuromuscular blocking agents, recent myocardial infarction, use of anti-psychotics, hypersensitivity to any of the drug under study.",true,"ALL","18 Years","60 Years",{"count":48,"type":49},66,"ESTIMATED","INTERVENTIONAL",[52],"EARLY_PHASE1","Comparison of effect of dexmedetomidine and midazolam in icu patients who put on mechanical ventilation and show agitation on weaning.Selection of better agent minimises the drug related side effects like respiratory depression but also helps in weaning for early extubation,give hemodynamic stability and reduce morbidity and mortality in icu..",[55],"Agitation, Emergence","NOT_YET_RECRUITING","2024-08-06",{"date":59,"type":60},"2024-08-07","ACTUAL",{"date":62,"type":49},"2024-11-01",{"date":64,"type":49},"2025-07-31",{"name":5,"class":6}]