[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100574211":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":26,"centralContacts":31,"locations":36,"responsibleParty":52,"collaborators":21,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":21,"eligibilityCriteria":60,"healthyVolunteers":61,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":21,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":21,"overallStatus":38,"whyStopped":21,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Anhui Provincial Hospital","OTHER_GOV",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"[18F]AlF-PSMA-N5 and [18F]F-DCFPyL PET\u002F CT scan","EXPERIMENTAL","Subjects PET\u002FCT imaging: On any two days for two consecutive weeks, each subject underwent a PET\u002F CT scan after intravenous injection of \\[18F\\]AlF-PSMA-N5 and \\[18F\\]F-DCFPyL.",[13,14],"Drug: [18F]AlF-PSMA-N5","Drug: [18F]F-DCFPyL",[16,22],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":21},"DRUG","[18F]AlF-PSMA-N5","Each subject receive a single intravenous injection of \\[18F\\]AlF-PSMA-N5, and undergo PET\u002FCT imaging within the specificed time.",[9],null,{"type":17,"name":23,"description":24,"armGroupLabels":25,"otherNames":21},"[18F]F-DCFPyL","Each subject receive a single intravenous injection of \\[18F\\]F-DCFPyL, and undergo PET\u002FCT imaging within the specificed time.",[9],[27],{"name":28,"affiliation":29,"role":30},"Qiang Xie, MD","The First Affiliated Hospital of China University of Science and Technology（Anhui Provincial Hospital）","STUDY_CHAIR",[32],{"name":28,"role":33,"phone":34,"phoneExt":21,"email":35},"CONTACT","13721108043","xieqiang1980@ustc.edu.cn",[37],{"facility":29,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"RECRUITING","Hefei","Anhui","230000","China","CN",{"type":45,"coordinates":46},"Point",[47,48],117.28083,31.86389,{"lat":48,"lon":47},[51],{"name":28,"role":33,"phone":34,"phoneExt":21,"email":35},{"type":53,"investigatorFullName":21,"investigatorTitle":21,"investigatorAffiliation":21,"oldNameTitle":21,"oldOrganization":21},"SPONSOR","100574211","early-phase-1-head-to-head-comparison-of-18falf-psma-n5-with-18ff-dcfpyl-petct-in-pca-diagnosis-recurrence-and-metastasis-100574211",false,"NCT06756334","Head-to-head Comparison of [18F]AlF-PSMA-N5 With [18F]F-DCFPyL PET\u002FCT in PCa Diagnosis, Recurrence, and Metastasis","Head-to-head Comparison of [18F]AlF-PSMA-N5 With [18F]F-DCFPyL PET\u002FCT in Prostate Cancer Diagnosis, Recurrence, and Metastasis: a Prospective Study","Inclusion Criteria:\n\n* Aged from 18 to 90 years old;\n* Complete MRI images and clinical data (such as PSA level, Gleason grade, etc.);\n* Prostate cancer detected by PSA or imaging examination, or clinically suspected recurrence after standardized treatment;\n* simultaneous \\[18F\\]AlF-PSMA-N5 and \\[18F\\]F-DCFPyL examinations within two weeks;\n* Willing to undergo surgery or needle biopsy for pathological examination after examination, or confirmed as prostate cancer by histopathology before or after treatment;\n* Sign informed consent.\n\nExclusion Criteria:\n\n* Patients who cannot cooperate with the examination;\n* Concurrent malignant tumors;\n* Previous alcohol allergy;\n* Patients with liver and kidney dysfunction;\n* Other circumstances deemed by the investigator to be inappropriate for trial participation.",true,"MALE","18 Years","90 Years",{"count":66,"type":67},30,"ESTIMATED","INTERVENTIONAL",[70],"EARLY_PHASE1","To prospectively evaluate the radiodrug biodistribution of a novel PET imaging agent \\[18F\\]AlF-PSMA-N5 in different organs of prostate cancer patients and its diagnostic efficacy in the diagnosis, recurrence and metastasis of prostate cancer, and to compare with \\[18F\\]F-DCFPyL.",[73,74],"Prostate Cancer","PET\u002FCT","2024-12-25",{"date":77,"type":78},"2025-01-03","ACTUAL",{"date":80,"type":78},"2024-12-19",{"date":82,"type":67},"2025-12-31",{"name":5,"class":6},1]