[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100528646":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":32,"centralContacts":36,"locations":45,"responsibleParty":61,"collaborators":31,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":31,"eligibilityCriteria":70,"healthyVolunteers":71,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":31,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":84,"overallStatus":47,"whyStopped":31,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"University of Cincinnati","OTHER",[8,14,18,22],{"label":9,"type":10,"description":11,"interventionNames":12},"Healthy controls","EXPERIMENTAL","No cystic fibrosis (CF)",[13],"Other: Mixed meal",{"label":15,"type":10,"description":16,"interventionNames":17},"Pancreatic sufficient CF","cystic fibrosis, but not pancreatic insufficient",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Pancreatic insufficient CF","cystic fibrosis and pancreatic insufficient",[13],{"label":23,"type":10,"description":24,"interventionNames":25},"CF-related diabetes","cystic fibrosis and diabetes",[13],[27],{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"Mixed meal","Each individual will ingest 5 mL\u002Fkg of Boost energy drink.",[23,9,19,15],null,[33],{"name":34,"affiliation":5,"role":35},"Jason Winnick, PhD","PRINCIPAL_INVESTIGATOR",[37,41],{"name":34,"role":38,"phone":39,"phoneExt":31,"email":40},"CONTACT","513-558-4437","jason.winnick@uc.edu",{"name":42,"role":38,"phone":43,"phoneExt":31,"email":44},"Shana Warner, PhD","513-558-5545","warners3@ucmail.uc.edu",[46],{"facility":5,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"RECRUITING","Cincinnati","Ohio","45267-0547","United States","US",{"type":54,"coordinates":55},"Point",[56,57],-84.51439,39.12711,{"lat":57,"lon":56},[60],{"name":34,"role":38,"phone":39,"phoneExt":31,"email":40},{"type":35,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"Jason Winnick","Principal Investigator","100528646","early-phase-1-hormonal-responses-to-a-mixed-meal-in-people-with-cystic-fibrosis-100528646",false,"NCT06163482","Hormonal Responses to a Mixed Meal in People With Cystic Fibrosis","Changes in Postprandial Hormone Levels in Cystic Fibrosis Related Diabetes.","Inclusion Criteria:\n\n* Diagnosed with cystic fibrosis\n* Aged 18 to 45 years\n* Males and females of any race and ethnicity\n* Receiving highly effective CFTR modular therapy\n\nExclusion Criteria:\n\n* Transplant recipient\n* Acute lung function decline or exacerbation within the last 3 months\n* Use of systemic glucocorticoids\n* Pregnancy\n* Known liver disease that would be expected to significantly impact metabolic variable as interpreted by a study doctor\n* The presence of any other disease or condition, as interpreted by any one of the study doctors, that would be expected to confound the responses to liquid mixed meal or make participation in the study dangerous to the individual\n* People who are cognitively impaired\n* People who do not speak English\n* For CFRD patients, a daily insulin requirement that exceeds 0.8 U\u002Fkg\u002Fday\n* Any prior history of diabetic ketoacidosis.",true,"ALL","18 Years","45 Years",{"count":76,"type":77},61,"ESTIMATED","INTERVENTIONAL",[80],"EARLY_PHASE1","In this exploratory study, the hormonal responses to a mixed meal will be examined in people with cystic fibrosis. The aim of this study is to find correlates with impaired glucose tolerance that is associated with this population.",[83],"Cystic Fibrosis",[85,86],"diabetes","cystic fibrosis","2026-03-18",{"date":89,"type":90},"2026-03-23","ACTUAL",{"date":92,"type":90},"2023-03-28",{"date":94,"type":77},"2026-12-30",{"name":5,"class":6},1]