[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100630314":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":33,"responsibleParty":51,"collaborators":54,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":19,"eligibilityCriteria":64,"healthyVolunteers":65,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":19,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":19,"overallStatus":35,"whyStopped":19,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"University of Utah","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Main Arm","EXPERIMENTAL","Powered and passive lower limb prosthesis and control",[13],"Device: Powered and passive lower limb prosthesis and control",[15],{"type":16,"name":11,"description":17,"armGroupLabels":18,"otherNames":19},"DEVICE","Effect of prosthesis function on mobility and ambulation",[9],null,[21],{"name":22,"affiliation":5,"role":23},"Tommaso Lenzi, PhD","PRINCIPAL_INVESTIGATOR",[25,29],{"name":22,"role":26,"phone":27,"phoneExt":19,"email":28},"CONTACT","3126190442","t.lenzi@utah.edu",{"name":30,"role":26,"phone":31,"phoneExt":19,"email":32},"Rosie Murray, PhD","8012133637","rosemarie.murray@utah.edu",[34],{"facility":5,"status":35,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"RECRUITING","Salt Lake City","Utah","84112","United States","US",{"type":42,"coordinates":43},"Point",[44,45],-111.89105,40.76078,{"lat":45,"lon":44},[48,49,50],{"name":22,"role":26,"phone":27,"phoneExt":19,"email":28},{"name":30,"role":26,"phone":31,"phoneExt":19,"email":32},{"name":22,"role":23,"phone":19,"phoneExt":19,"email":19},{"type":23,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"Tommaso Lenzi","Associate Professor",[55],{"name":56,"class":57},"Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)","NIH","100630314","early-phase-1-motorized-prostheses-for-lower-limb-amputees-100630314",false,"NCT07486063","Motorized Prostheses for Lower-limb Amputees","Lightweight Motorized Prostheses for Lower-limb Amputees","Our inclusion criteria will be\n\n* Above-knee amputation\n* K2\u002FK3\u002FK4 ambulators\n* At least 18 years old\n* At least one year since amputation\n* At least six months since the definitive prosthesis fitting\n* Currently prescribed and using a mechanically passive or microprocessor-controlled prosthesis\n\nOur exclusion criteria will be\n\n* Over 350 lbs. body weight, the weight limit for our safety suspension systems\n* Cognitive deficits or visual impairment that could impair their ability to give informed consent or to follow simple instructions during the experiments\n* Pregnant women due to elevated safety concerns for this population\n* Co-morbidity that limits their ability to participate in the study protocol (e.g., stroke, pacemaker placement that would interfere with the powered prosthesis, severe ischemia, cardiac disease, etc.)\n* Adults who are unable to consent\n* Individuals who are not yet adults (infants, children, teenagers)\n* Individuals who use a wheelchair for mobility both outdoors and indoors because they may not be able to perform the necessary activities with their passive prosthesis or the powered prosthesis\n* Prisoners, due to concerns with informed consent",true,"ALL","18 Years","80 Years",{"count":70,"type":71},40,"ESTIMATED","INTERVENTIONAL",[74],"EARLY_PHASE1","The investigators will assess biomechanical and functional mobility outcomes in individuals with unilateral, above-knee amputations using different knee\u002Fankle configurations of a lightweight powered prosthesis and different volitional controllers in individuals with unilateral, above-knee amputations.",[77],"Lower-Limb Amputation","2026-03-17",{"date":80,"type":81},"2026-03-20","ACTUAL",{"date":83,"type":81},"2025-07-01",{"date":85,"type":71},"2032-06",{"name":5,"class":6},1]