[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100557659":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":33,"locations":38,"responsibleParty":53,"collaborators":55,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":25,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":25,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":25,"overallStatus":40,"whyStopped":25,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Teachers College, Columbia University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Immediate treatment","EXPERIMENTAL","Participants will receive speech treatment immediately after their second pre-treatment assessment.",[13],"Behavioral: Immediate treatment",{"label":15,"type":16,"description":17,"interventionNames":18},"Deferred treatment","ACTIVE_COMPARATOR","Participants will receive speech treatment one month after their second pre-treatment assessment. This arm receives the same speech treatment as Arm 1.",[19],"Behavioral: Deferred treatment",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Participants will access a web-based app using their phone to record 100 sentences every treatment session. Noise-augmented feedback will be provided to increase accuracy of speech productions.",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"This group of participants will receive the same treatment as those in the immediate treatment group. The only difference is the timeline of treatment onset. Therefore, participants will access a web-based app using their phone to record 100 sentences every treatment session. Noise-augmented feedback will be provided to increase accuracy of speech productions.",[15],[30],{"name":31,"affiliation":5,"role":32},"Gemma Moya-Galé, Ph.D.","PRINCIPAL_INVESTIGATOR",[34],{"name":31,"role":35,"phone":36,"phoneExt":25,"email":37},"CONTACT","212-678-3323","gm2446@tc.columbia.edu",[39],{"facility":5,"status":40,"city":41,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"RECRUITING","New York","10027","United States","US",{"type":46,"coordinates":47},"Point",[48,49],-74.00597,40.71427,{"lat":49,"lon":48},[52],{"name":31,"role":35,"phone":36,"phoneExt":25,"email":37},{"type":54,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[56],{"name":57,"class":6},"Temple University","100557659","early-phase-1-noise-augmented-automatic-speech-recognition-for-speech-treatment-in-parkinsons-disease-100557659",false,"NCT06540989","Noise-augmented Automatic Speech Recognition for Speech Treatment in Parkinson's Disease","Understand Me for Life: Using Noise-augmented Automatic Speech Recognition to Improve Intelligibility in Parkinson's Disease","Inclusion Criteria:\n\n* Participants will qualify for the study if:\n\n  * They are 50-80 years old,\n  * They have a medical diagnosis of PD,\n  * They are within stages I-IV of Hoehn \\& Yahr Scale,\n  * Their antiparkinsonian medication schedule is stable,\n  * They present with mild to moderate dysarthria,\n  * They score ≥ 25 in the MMSE,\n  * They score ≤ 24 in the BDI-III.\n\nExclusion Criteria:\n\n* Participants will be excluded from the study if they:\n\n  * Present with atypical parkinsonism at the time of screening (or other neurological condition),\n  * Underwent neurosurgery treatment (DBS),\n  * Received intensive voice-focused treatment less than three months prior to their involvement in the current study,\n  * Present with any speech or voice pathology that is unrelated to PD.","ALL","50 Years","80 Years",{"count":69,"type":70},42,"ESTIMATED","INTERVENTIONAL",[73],"EARLY_PHASE1","The goal of this clinical trial is to learn whether noise-augmented feedback using automatic speech recognition improves intelligibility and social participation in individuals with Parkinson's disease. The main questions the investigators will address are:\n\nDoes noise-augmented feedback lead to increased intelligibility, as measured by transcription accuracy scores?\n\nDoes a self-managed speech protocol lead to increased social participation, as measured by the Communicative Participation Item Bank and the Communicative Effectiveness Index questionnaires?\n\nParticipants will:\n\nReceive 2-4 initial speech assessments in-person in our lab. Engage in speech treatment sessions at home using their phone and computer four days a week for four weeks. Four of those sessions will be directly monitored online by a speech-language pathologist. The rest of the sessions are completed by the participant.\n\nCome to the lab for two post-treatment assessments following completion of treatment.\n\nCome to the lab six months after treatment completion for an additional assessment.",[76],"Parkinson Disease","2024-08-13",{"date":79,"type":80},"2024-08-15","ACTUAL",{"date":82,"type":70},"2024-09-01",{"date":84,"type":70},"2027-06-30",{"name":5,"class":6},1]