[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100477189":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":38,"centralContacts":42,"locations":48,"responsibleParty":64,"collaborators":29,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":70,"acronym":29,"eligibilityCriteria":71,"healthyVolunteers":68,"sex":72,"minAge":73,"maxAge":29,"enrollmentInfo":74,"targetDuration":29,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":84,"overallStatus":50,"whyStopped":29,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"University of Minnesota","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Stimulation Group A","EXPERIMENTAL","Participants with already implanted DBS will receive stimulation order 1. PS, OS, OS.",[13],"Other: PS and OS stimulation order 1",{"label":15,"type":10,"description":16,"interventionNames":17},"Stimulation Group B","Participants with already implanted DBS will receive stimulation order 1. OS, PS, OS.",[18],"Other: PS and OS stimulation order 2",{"label":20,"type":10,"description":21,"interventionNames":22},"Stimulation Group C","Participants with already implanted DBS will receive stimulation order 1. OS, OS, PS.",[23],"Other: PS and OS stimulation order 3",[25,30,34],{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":29},"PS and OS stimulation order 1","PS, OS, OS",[9],null,{"type":6,"name":31,"description":32,"armGroupLabels":33,"otherNames":29},"PS and OS stimulation order 2","OS, PS, OS",[15],{"type":6,"name":35,"description":36,"armGroupLabels":37,"otherNames":29},"PS and OS stimulation order 3","OS, OS, PS",[20],[39],{"name":40,"affiliation":5,"role":41},"Robert McGovern, MD","PRINCIPAL_INVESTIGATOR",[43],{"name":44,"role":45,"phone":46,"phoneExt":29,"email":47},"Alec Jonason","CONTACT","612-624-3127","jonas074@umn.edu",[49],{"facility":5,"status":50,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"RECRUITING","Minneapolis","Minnesota","55455","United States","US",{"type":57,"coordinates":58},"Point",[59,60],-93.26384,44.97997,{"lat":60,"lon":59},[63],{"name":44,"role":45,"phone":46,"phoneExt":29,"email":47},{"type":65,"investigatorFullName":29,"investigatorTitle":29,"investigatorAffiliation":29,"oldNameTitle":29,"oldOrganization":29},"SPONSOR","100477189","early-phase-1-optimization-of-deep-brain-stimulation-parameters-in-patients-with-medically-refractory-epilepsy-100477189",false,"NCT05493722","Optimization of Deep Brain Stimulation Parameters in Patients With Medically Refractory Epilepsy","Inclusion Criteria:\n\n* medically refractory epilepsy\n* already have a deep brain stimulator in place\n\nExclusion Criteria:\n\n* severe dementia at investigator discretion","ALL","18 Years",{"count":75,"type":76},20,"ESTIMATED","INTERVENTIONAL",[79],"EARLY_PHASE1","Deep brain stimulation (DBS) is used to treat epilepsy in cases where patients are medically refractory and are not candidates for surgical resection. This therapy has been shown to be effective in seizure reduction, yet very few patients achieve the ultimate goal of seizure freedom. Implantable neural stimulators (INSs) have many parameters that may be adjusted, and could be tuned to achieve very patient specific therapies. This study will develop a platform for stimulation setting optimization based on power spectral density (PSD) measures.",[82,83],"Refractory Epilepsy","Deep Brain Stimulation",[82,85],"deep brain stimulation","2025-10-22",{"date":88,"type":89},"2025-10-24","ACTUAL",{"date":91,"type":89},"2023-09-15",{"date":93,"type":76},"2030-01-15",{"name":5,"class":6},1]