[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100626321":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":23,"centralContacts":23,"locations":23,"responsibleParty":36,"collaborators":38,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":5,"eligibilityCriteria":48,"healthyVolunteers":44,"sex":49,"minAge":50,"maxAge":23,"enrollmentInfo":51,"targetDuration":23,"studyType":54,"phases":55,"briefSummary":57,"conditions":58,"keywords":23,"overallStatus":60,"whyStopped":23,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":23},{"fullName":5,"class":6},"PROREGEN","NETWORK",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Use of orthobiological products in musculoskeletal conditions.","EXPERIMENTAL","After an evaluation by a medical professional, the patient will be advised on the best orthobiological treatment for their case.",[13,14,15,16],"Biological: PRP injection","Biological: Bone Marrow Concentrate (BMAC)","Biological: Hyaluronic Acid (Viscosupplementation)","Biological: Nanofat",[18,24,28,32],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":23},"BIOLOGICAL","PRP injection","Obtained by centrifuging blood, it concentrates platelets and growth factors for regeneration.",[9],null,{"type":19,"name":25,"description":26,"armGroupLabels":27,"otherNames":23},"Bone Marrow Concentrate (BMAC)","Bone marrow aspirate, rich in mesenchymal stem cells and progenitor cells for tissue repair.",[9],{"type":19,"name":29,"description":30,"armGroupLabels":31,"otherNames":23},"Hyaluronic Acid (Viscosupplementation)","Used for joint lubrication and cartilage protection, very common in osteoarthritis.",[9],{"type":19,"name":33,"description":34,"armGroupLabels":35,"otherNames":23},"Nanofat","It is an even more refined and liquefied form of processed fat, used primarily for high-precision tissue repair.",[9],{"type":37,"investigatorFullName":23,"investigatorTitle":23,"investigatorAffiliation":23,"oldNameTitle":23,"oldOrganization":23},"SPONSOR",[39],{"name":40,"class":41},"Centro Universitário Univates","OTHER","100626321","early-phase-1-orthobiological-therapies-in-musculoskeletal-disorders-100626321",false,"NCT07434115","Orthobiological Therapies in Musculoskeletal Disorders","Clinical and Functional Evaluation of Orthobiological Therapies in Musculoskeletal Conditions","Inclusion Criteria:\n\n* Age 18 or older;\n* Clinical and\u002For radiological diagnosis of an eligible musculoskeletal condition;\n* Formal clinical indication for treatment with orthobiological agents, according to routine care;\n* Regular access to the WhatsApp application, ensuring the necessary communication for sending and receiving digital questionnaires and other study instructions;\n* Ability to understand the study and sign the Informed Consent Form.\n\nExclusion Criteria:\n\n* Medical contraindication to the use of orthobiologics (e.g., active infection, severe hematological diseases, active cancer);\n* Recent use (≤3 months) of orthobiologic therapies in the same area to be treated;\n* Pregnant or breastfeeding women;\n* Cognitive or psychiatric diseases that prevent adequate clinical follow-up;\n* Simultaneous participation in another interventional clinical study with the same therapeutic purpose.","ALL","18 Years",{"count":52,"type":53},300,"ESTIMATED","INTERVENTIONAL",[56],"EARLY_PHASE1","To evaluate the clinical and functional effects of using orthobiological therapies (hyaluronic acid, platelet-rich plasma, bone marrow aspirate, nanofat, among others) in the treatment of various musculoskeletal diseases in patients routinely treated at the Proregen Medical Clinic and its affiliates.\n\nThe sample will consist of adult patients (≥18 years), of both sexes, with different musculoskeletal diagnoses involving joints, tendons, ligaments, cartilage or bone, among others.",[59],"Musculoskeletal Diseases or Conditions","NOT_YET_RECRUITING","2026-02-19",{"date":63,"type":64},"2026-02-25","ACTUAL",{"date":66,"type":53},"2026-01-30",{"date":68,"type":53},"2030-01",{"name":5,"class":6}]