[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100565792":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":21,"locations":27,"responsibleParty":40,"collaborators":20,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":20,"eligibilityCriteria":48,"healthyVolunteers":44,"sex":49,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":20,"studyType":55,"phases":56,"briefSummary":58,"conditions":59,"keywords":20,"overallStatus":63,"whyStopped":20,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},{"fullName":5,"class":6},"SmartNuclide Biopharma","INDUSTRY",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"dose escalation","EXPERIMENTAL","subgroups mass does escalation",[13],"Drug: [68Ga]Ga-NODAGA-SNA014",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DRUG","[68Ga]Ga-NODAGA-SNA014","Perform whole-body PET\u002FCT scans on the subjects at 30 minutes (± 5 minutes), 60 minutes (± 10 minutes), 120 minutes (± 20 minutes), and 240 minutes (± 30 minutes) after administration. Among them, PET scanning can be performed on 1-2 subjects in a certain dose group or each dose group for 30-60 minutes. Among the four CT scans, one CT scan is a conventional low-dose CT scan (120mA), and the remaining three are extremely low-dose CT scans (10-20mA). The main researchers and nuclear medicine physicians can decide whether to change the subsequent image acquisition time and duration of the subjects based on the image information obtained from the enrolled subjects.",[9],null,[22],{"name":23,"role":24,"phone":25,"phoneExt":20,"email":26},"Miao liyan Chief Pharmacist, doctorate","CONTACT","0512-679-72858","miaolysuzhou@163.com",[28],{"facility":29,"status":20,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":20,"geoPoint":20,"contacts":35},"The First Affiliated Hospital of Soochow University","Jiangsu","Province","215000","China","CN",[36],{"name":37,"role":24,"phone":38,"phoneExt":20,"email":39},"ZhangHua Chief Pharmacist, doctorate","0512-677-80040","Sdfyy8040@126.com",{"type":41,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100565792","early-phase-1-phase-iit-trial-of-sna014-100565792",false,"NCT06646783","Phase IIT Trial of SNA014","Clinical Study of 68GA-labeled Claudin 18.2 Developer Combined with PET\u002FCT for Imaging of Gastric or Gastroesophageal Junction Adenocarcinoma and Pancreatic Cancer","Inclusion Criteria:\n\n* Age range of 18 to 75 years old (including boundary values);\n* Individuals with behavioral capacity who voluntarily participate in this clinical study and sign an informed consent form (ICF);\n* Diagnosed G\u002FGEJ adenocarcinoma and pancreatic cancer;\n* Gastroscopy\u002FCT\u002FMRI\u002FPET-CT examination results within the past month (if any);\n* Pathological test results and Claudin18.2 immunohistochemistry results within the past year (if available).\n\nExclusion Criteria:\n\n* Merge patients with other clearly diagnosed malignant tumors:\n* Uncontrolled severe infections or individuals with other serious illnesses;\n* Those with an expected survival period of less than or equal to three months;\n* Pregnant or lactating patients, as well as reproductive age patients who refuse to take appropriate contraceptive measures during this trial;\n* investigators determine that patients who are not suitable to participate in this study;","ALL","18 Years","75 Years",{"count":53,"type":54},28,"ESTIMATED","INTERVENTIONAL",[57],"EARLY_PHASE1","68Ga labeled Claudin 18.2 contrast agent combined with PET\u002FCT for gastric or gastroesophageal junction",[60,61,62],"Adenocarcinoma of the Stomach","Adenocarcinoma of GE Junction","Pancreatic Cancer Stage","NOT_YET_RECRUITING","2024-10-15",{"date":66,"type":67},"2024-10-17","ACTUAL",{"date":69,"type":54},"2024-10-20",{"date":71,"type":54},"2025-11-20",{"name":5,"class":6},1]