[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100608948":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":39,"locations":48,"responsibleParty":71,"collaborators":73,"id":78,"slug":79,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":80,"sex":86,"minAge":87,"maxAge":26,"enrollmentInfo":88,"targetDuration":26,"studyType":91,"phases":92,"briefSummary":94,"conditions":95,"keywords":97,"overallStatus":103,"whyStopped":26,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":113},{"fullName":5,"class":6},"NHS Greater Glasgow and Clyde","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention","EXPERIMENTAL","One hour of transcutaneous electrical stimulation alongside conventional occupational therapy",[13],"Device: Transcutaneous spinal cord stimulation (tESCS) active group",{"label":15,"type":16,"description":17,"interventionNames":18},"Control","SHAM_COMPARATOR","Receiving 1 minute of stimulation alongside the conventional occupational therapy",[19],"Device: Sham transcutaneous spinal cord stimulation (tESCS)",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Transcutaneous spinal cord stimulation (tESCS) active group","Participants in the active arm will receive 60 min of tESCS alongside the conventional occupation therapy, 20 sessions for 4 weeks, 5 times per week",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Sham transcutaneous spinal cord stimulation (tESCS)","The control group will receive only 1 min of tESCS while doing conventional occupational therapy for 60 min. Number of session 20, 4 weeks, 5 times a week",[15],[32,36],{"name":33,"affiliation":34,"role":35},"Aleksandra Vuckovic University O VUCKOVIC, PhD Biomed Eng","School of Engineering, University of Glasgow","STUDY_DIRECTOR",{"name":37,"affiliation":5,"role":38},"Mariel A Purcell, MB CHB BAO","PRINCIPAL_INVESTIGATOR",[40,44],{"name":37,"role":41,"phone":42,"phoneExt":26,"email":43},"CONTACT","+44 141 201 2536","Margaret.Purcell@ggc.scot.nhs.uk",{"name":45,"role":41,"phone":46,"phoneExt":26,"email":47},"ALEKSANDRA VUCKOVIC, PhD Biomed Eng","+447906441955","aleksandra.vuckovic@glasgow.ac.uk",[49],{"facility":50,"status":26,"city":51,"state":26,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"Queen Elizabeth National Spinal Injuries Unit","Glasgow","G51 4TF","United Kingdom","UK",{"type":56,"coordinates":57},"Point",[58,59],-4.25763,55.86515,{"lat":59,"lon":58},[62,63,66,69],{"name":37,"role":41,"phone":42,"phoneExt":26,"email":43},{"name":64,"role":41,"phone":26,"phoneExt":26,"email":65},"Euan McCaughey, PhD Biomed Eng","euan.mccaughey@nhs.scot",{"name":67,"role":68,"phone":26,"phoneExt":26,"email":26},"Euan O McCaughey, PhD Biomed Eng","SUB_INVESTIGATOR",{"name":70,"role":38,"phone":26,"phoneExt":26,"email":26},"Mariel Purcell, MB CHB BAO",{"type":72,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[74,76],{"name":75,"class":6},"University of Glasgow",{"name":77,"class":6},"The Queen Elizabeth Hospital","100608948","early-phase-1-tescs-for-upper-limb-rehab-in-spinal-cord-injury-100608948",false,"NCT07208188","tESCS for Upper Limb Rehab in Spinal Cord Injury","Transcutaneous Spinal Cord Stimulation for Rehabilitation of Upper Limbs in Early Spinal Cord Injury: Randomised Feasibility Study","SCIRUS","Inclusion Criteria:\n\n* Aged 18 years or over, both sexes.\n* At least 6 weeks post-implant (in participants having a surgery for an implant to stabilise the spine).\n* ISNCSCI upper extremity motor score between 5 and 30 (both arms\u002Fhands)\n* GRASSP-strength score \\>=15 \\& \\\u003C70\n* Medically stable, cognitively intact and able to breathe independently.\n* Attending upper limb therapy sessions at the QENSIU\n* Planned stay longer than the duration of the intervention\n* Able to sit for more than 2 hours a day\n\nExclusion Criteria:\n\n* Unstable cervical spine injury\n* Needing ventilation assistance during daytime\n* Any implanted active metallic device without unconfirmed MRI compatibility (in our previous studies, we safely applied tESCS to participants with MRI-compatible devices\u002Fimplants)\n* Pregnancy and\u002For lactation.\n* Non-injury-related neurological impairment\n* Severe spasticity which have been unstable prior to enrolment\n* Botulinum toxin injections-\n* Clinically significant severe depression\n* Patients who have cardiovascular disease\n* Patients with severe ongoing Autonomic Dysreflexia\n* Skin conditions or allergies that may affect electrode placement.\n* Current infections\n* Patients who have been involved in any other interventional study","ALL","18 Years",{"count":89,"type":90},20,"ESTIMATED","INTERVENTIONAL",[93],"EARLY_PHASE1","Regaining hand and arm function is an important step towards regaining independence following high-level spinal cord injury (tetraplegia). The delivery of small electrical pulses over the skin above the spinal cord, called transcutaneous spinal cord stimulation (tESCS), appears to improve the arm and hand function of people who have had tetraplegia for several years when delivered at the same time as upper limb therapy. However, tESCS has not been tested in people who have a new spinal cord injury. It should be straightforward to deliver tESCS during standard upper limb therapy sessions to inpatients receiving primary rehabilitation. The investigators want to test the practical aspects of delivering this intervention and also to compare recovery between a group of people who only receive upper limb therapy and a group who receive upper limb therapy and tESCS. If successful, tESCS could in the future be used as part of regular therapy following an acute spinal cord injury. Benefits could include faster and better recovery, reduced stay in hospital, and reduced NHS costs.",[96],"Spinal Cord Injuries (SCI)",[98,99,100,101,102],"Tetraplegia","incomplete","subacute","transcutaneous spinal cord stimulation","randmised feasibility study","NOT_YET_RECRUITING","2025-09-26",{"date":106,"type":107},"2025-10-06","ACTUAL",{"date":109,"type":90},"2025-11",{"date":111,"type":90},"2027-12",{"name":5,"class":6},1]