[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100623444":3},{"organization":4,"armGroups":7,"interventions":29,"overallOfficials":43,"centralContacts":49,"locations":11,"responsibleParty":56,"collaborators":11,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":11,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":11,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":79,"overallStatus":81,"whyStopped":11,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":11},{"fullName":5,"class":6},"Assiut University","OTHER",[8,14,19,23],{"label":9,"type":10,"description":11,"interventionNames":12},"topical ivermectin","EXPERIMENTAL",null,[13],"Drug: Ivermectin",{"label":15,"type":10,"description":16,"interventionNames":17},"microneedling","patients with cutaneous warts will be treated with microneedling.",[18],"Device: microneedling",{"label":20,"type":10,"description":21,"interventionNames":22},"microneedling with ivermectin","patients with cutaneous warts will be treated with topical ivermectin with microneedling.",[13,18],{"label":24,"type":25,"description":26,"interventionNames":27},"topical salicylic acid","ACTIVE_COMPARATOR","patients with cutaneous warts will be treated with topical salicylic acid.",[28],"Drug: Salicylic Acid",[30,35,39],{"type":31,"name":32,"description":33,"armGroupLabels":34,"otherNames":11},"DRUG","Ivermectin","patients with non-genital cutaneous warts will be treated by topical application of ivermectin : topical ivermectin 1% will be applied under occlusion overnight daily then revaluated every 2 weeks for maximum 12 weeks",[20,9],{"type":36,"name":15,"description":37,"armGroupLabels":38,"otherNames":11},"DEVICE","patients with non-genital cutaneous warts will be treated by microneedling (2mm depth) every 2-weeks until complete clearance or for a maximum of 12weeks",[15,20],{"type":31,"name":40,"description":41,"armGroupLabels":42,"otherNames":11},"Salicylic Acid","patients with non-genital cutaneous warts will be treated by topical application of ivermectin : cotton soaked with topical salicylic acid will be applied under occlusion overnight daily then revaluated every 2 weeks for maximum 12 weeks",[24],[44,47],{"name":45,"affiliation":5,"role":46},"Alaa mohamed ghazaly, MD","STUDY_DIRECTOR",{"name":48,"affiliation":5,"role":46},"Ayman Mohamed Mahran, MD",[50],{"name":51,"role":52,"phone":53,"phoneExt":54,"email":55},"aya mohamed sayed, bechlor","CONTACT","01010556275","+2","aya.m.abdelazia17@gmail.com",{"type":57,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Aya Mohamed Sayed Abdelaziz","Doctor","100623444","early-phase-1-the-efficacy-of-ivermectin-alone-or-with-microneedling-in-treatment-of-cutaneous-warts-100623444",false,"NCT07396714","the Efficacy of Ivermectin Alone or With Microneedling in Treatment of Cutaneous Warts.","Evaluation of the Efficacy & Safety of Topical Ivermectin Alone or in Combination With Microneedling as Novel Therapeutic Options for Cutaneous Non-genital Warts Versus Topical Salicylic Acid ؛ Randomized Controlled Clinical Trial.","Inclusion Criteria:\n\n* patients with cutaneous non genital warts aged 11:80 y.\n* No concurrent systemic or topical treatment of warts\n\nExclusion Criteria:\n\n* Genital warts.\n\n  * Pregnancy and lactation.\n  * History of any bleeding, clotting disorder or using anticoagulants\n  * Chronic systemic diseases such as chronic renal failure, hepaticinsufficiency, and cardiovascular disorders.\n  * patients who received any treatment for warts in the last month before the study.\n  * Patients with history of neuropathy or peripheral ischemia.\n  * Patients with signs of inflammation or infection.\n  * Patients with history of a serious systemic or anaphylactic reaction or allergy to ivermectin.","ALL","11 Years","80 Years",{"count":71,"type":72},88,"ESTIMATED","INTERVENTIONAL",[75],"EARLY_PHASE1","To compare between the efficacy and safety of topical ivermectin alone, microneedling with topical ivermectin and topical salicylic acid in treatment of cutaneous warts.\n\ntopical ivermectin 1% will be applied on warts whole night clinical assessment will be done every 2 weeks\n\nMicroneedling will be performed on the lesion using a microneedling pen type device with a 1-cm tip diameter at a 2-mm depth setting for 2-3 minutes until pinpoint bleebing occurs 1 mL of topical ivermectin 1% will be applied on to the wart tissue.\n\nSessions: Sessions will be performed every 2 weeks until complete cure or for maximum 6 sessions (total 3 month)",[78],"Warts",[80],"topical ivermectin with microneedling in warts treatment","NOT_YET_RECRUITING","2026-02-04",{"date":84,"type":85},"2026-02-09","ACTUAL",{"date":87,"type":72},"2026-02-01",{"date":89,"type":72},"2027-06-01",{"name":5,"class":6}]