[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100573116":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":31,"centralContacts":32,"locations":38,"responsibleParty":52,"collaborators":31,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":31,"eligibilityCriteria":62,"healthyVolunteers":58,"sex":63,"minAge":31,"maxAge":31,"enrollmentInfo":64,"targetDuration":31,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":31,"overallStatus":73,"whyStopped":31,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Assiut University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Malignant Pleural effusion with pleurodesis","ACTIVE_COMPARATOR","these are patients who have malignant pleural effusion and will have talc injected into the pleural cavity to induce pleurodesis",[13,14],"Procedure: Intercostal chest tube","Combination Product: Pleurodesis",{"label":16,"type":10,"description":17,"interventionNames":18},"Malignant Pleural effusion with only chest tube for drainage","these are patients who have malignant pleural effusion but will only have intercostal chest tube inserted for drainage",[13],[20,27],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Intercostal chest tube","the use of chest tubes to drain malignant pleural effusion",[16,9],[26],"Pleurodesis",{"type":28,"name":26,"description":29,"armGroupLabels":30,"otherNames":31},"COMBINATION_PRODUCT","the injection of Talc in pleural space to induce inflammation reaction and produce pleurodesis",[9],null,[33],{"name":34,"role":35,"phone":36,"phoneExt":31,"email":37},"Hussein E Mohamed, MD","CONTACT","+201222303172","husseinessam07@gmail.com",[39],{"facility":40,"status":31,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":31},"Assiut University Hospital","Asyut","Asyut Governorate","71515","Egypt","EG",{"type":47,"coordinates":48},"Point",[49,50],31.18368,27.18096,{"lat":50,"lon":49},{"type":53,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"PRINCIPAL_INVESTIGATOR","Hussein Essameldin Hussein Mohamed","Assistant Lecturer","100573116","early-phase-1-the-outcome-of-inserting-intercostal-tube-or-pleurodesis-for-malignant-pleural-effusion-100573116",false,"NCT06742099","The Outcome of Inserting Intercostal Tube or Pleurodesis for Malignant Pleural Effusion","Outcome of Intercostal Tube Insertion and Pleurodesis for Malignant Pleural Effusion","Inclusion Criteria:\n\n* All patients presented with malignant pleural effusion to Assiut University Hospital regardless of sex and age\n\nExclusion Criteria:\n\n* All patients presented with pleural effusion other than malignant pleural effusion, including patients with debilitating diseases and terminal patients.","ALL",{"count":65,"type":66},20,"ESTIMATED","INTERVENTIONAL",[69],"EARLY_PHASE1","Approximately half of all patients with metastatic cancer develop a malignant pleural effusion which is likely to lead to a significant reduction in quality of life secondary to symptoms such as dyspnoea and cough. The aim of pleurodesis in these patients is to prevent re-accumulation of the effusion and thereby of symptoms,and avoid the need for repeated hospitalization for thoracocentesis. Numerous clinical studies have been performed to try to determine the optimal pleurodesis strategy, and synthesis of the available evidence should facilitate this. The treatment of MPE is aimed at palliating symptoms since no intervention has been shown to improve survival in this population and since survival is generally limited in cancers that have spread to the pleural space. In this palliative setting, only patients symptomatic from their MPE should be submitted to further intervention. As well, further interventions in symptomatic patients should be limited to those patients who have experienced symptomatic improvement following initial therapeutic thoracentesis. The two main treatment approaches to MPE are to obliterate the pleural space via a pleurodesis procedure or to chronically drain the pleural cavity with Intercostal tube. The aims of this review were to ascertain the optimal procedure in cases of malignant pleural effusion in terms of patients' quality of life post procedure, recurrence of effusion.",[72],"Malignant Pleural Effusions (Mpe)","NOT_YET_RECRUITING","2024-12-17",{"date":76,"type":77},"2024-12-19","ACTUAL",{"date":79,"type":66},"2024-12-30",{"date":81,"type":66},"2025-09-30",{"name":5,"class":6},1]