[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100561025":3},{"organization":4,"armGroups":7,"interventions":28,"overallOfficials":40,"centralContacts":48,"locations":58,"responsibleParty":76,"collaborators":34,"id":78,"slug":79,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":34,"eligibilityCriteria":84,"healthyVolunteers":80,"sex":85,"minAge":86,"maxAge":34,"enrollmentInfo":87,"targetDuration":34,"studyType":90,"phases":91,"briefSummary":93,"conditions":94,"keywords":96,"overallStatus":61,"whyStopped":34,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation","OTHER",[8,14,18,24],{"label":9,"type":10,"description":11,"interventionNames":12},"Placebo group (1)","PLACEBO_COMPARATOR","Placebo group: participants with COPD AE is treated with placebo that mimic JSHT",[13],"Other: Placebo",{"label":15,"type":10,"description":16,"interventionNames":17},"Placebo group (2)","participants with stable COPD treated with placebo that mimic JSHT",[13],{"label":19,"type":20,"description":21,"interventionNames":22},"JSHT group of stable COPD","EXPERIMENTAL","participants with stable COPD treated with JSHT",[23],"Combination Product: Jing Si herbal tea (JSHT)",{"label":25,"type":20,"description":26,"interventionNames":27},"JSHT group of COPDAE","participants with COPD AE is treated with JSHT",[23],[29,35],{"type":30,"name":31,"description":32,"armGroupLabels":33,"otherNames":34},"COMBINATION_PRODUCT","Jing Si herbal tea (JSHT)","JSHT has been approved by the Ministry of Health and Welfare of Taiwan (registration number MOHW-PM-060635).",[25,19],null,{"type":6,"name":36,"description":37,"armGroupLabels":38,"otherNames":39},"Placebo","Placebo of JSHT",[9,15],[37],[41,45],{"name":42,"affiliation":43,"role":44},"Chou-Chin Lan, MD","Taichung Tzu Chi Hospital","PRINCIPAL_INVESTIGATOR",{"name":46,"affiliation":43,"role":47},"Yao-Kuang Wu, MD","STUDY_DIRECTOR",[49,55],{"name":50,"role":51,"phone":52,"phoneExt":53,"email":54},"Chou-Chin Lan, MD, PHD","CONTACT","800-555-5555","8119","bluescopy@yahoo.com.tw",{"name":46,"role":51,"phone":52,"phoneExt":56,"email":57},"2259","drbfci@yahoo.com.tw",[59],{"facility":60,"status":61,"city":62,"state":63,"zip":64,"country":65,"countryCode":66,"cosmosGeoPoint":67,"geoPoint":72,"contacts":73},"Taipei Tzu Chi Hospital","RECRUITING","New Taipei City","Xindan","23142","Taiwan","TW",{"type":68,"coordinates":69},"Point",[70,71],121.45703,25.06199,{"lat":71,"lon":70},[74,75],{"name":42,"role":51,"phone":52,"phoneExt":34,"email":54},{"name":50,"role":44,"phone":34,"phoneExt":34,"email":34},{"type":77,"investigatorFullName":34,"investigatorTitle":34,"investigatorAffiliation":34,"oldNameTitle":34,"oldOrganization":34},"SPONSOR","100561025","early-phase-1-therapeutic-effects-of-jing-si-herbal-tea-for-copd-100561025",false,"NCT06584786","Therapeutic Effects of Jing Si Herbal Tea for COPD","Therapeutic Effects of Jing Si Herbal Tea for Chronic Obstructive Pulmonary Disease: A Comprehensive Investigation From Clinical to Basic Research","Inclusion Criteria:\n\n* COPD patients willing to enter this study\n\nExclusion Criteria:\n\n* not COPD patients, no willing to enter this study","ALL","20 Years",{"count":88,"type":89},120,"ESTIMATED","INTERVENTIONAL",[92],"EARLY_PHASE1","Chronic obstructive pulmonary disease (COPD), a leading cause of global mortality, significantly impairs health-related quality of life (HRQL). COPD is characterized by airway inflammation and lung tissue damage. Jing Si herbal tea (JSHT) is known to have anti-inflammatory effects but has not been explored for treating COPD. This study investigated the potential of JSHT as an adjuvant therapy for COPD. This randomized controlled study focused on patients with COPD in the exacerbation and stable phases. The control group received the standard treatment, and the JSHT group received the standard treatment plus JSHT. Both groups underwent HRQL assessments, blood tests, and cellular studies involving five different groups to assess the effect of JSHT on damage-associated molecular patterns (DAMPs) and inflammatory markers.",[95],"Airway Disease",[97,98,99],"COPD","Jing Si herbal tea","damage-associated molecular patterns","2024-09-02",{"date":102,"type":103},"2024-09-05","ACTUAL",{"date":105,"type":103},"2022-01-01",{"date":107,"type":89},"2024-12-31",{"name":5,"class":6},1]