[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100526614":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":34,"centralContacts":38,"locations":48,"responsibleParty":67,"collaborators":42,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":73,"acronym":42,"eligibilityCriteria":74,"healthyVolunteers":71,"sex":75,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":42,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":88,"overallStatus":51,"whyStopped":42,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"University of Oklahoma","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Magnesium Sulfate in the first hour","EXPERIMENTAL","These patients will receive 40-50 mg\u002Fkg IV magnesium sulfate within the first hour of treatment alongside all first line asthma exacerbation therapies (ie inhaled beta agonists, IV steroids).",[13],"Drug: Magnesium Sulfate within the first hour",{"label":15,"type":16,"description":17,"interventionNames":18},"No Magnesium Sulfate","PLACEBO_COMPARATOR","These patients will not receive IV magnesium sulfate within the first hour of treatment but may receive it later if the provider feels it is clinically necessary.",[19],"Other: No Magnesium sulfate within the first hour",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Magnesium Sulfate within the first hour","The experimental group will receive 40-50 mg\u002Fkg of IV magnesium sulfate will be given to the experimental group alongside the first line asthma therapies (ie inhaled beta agonists, IV steroids). This will be given with a 20 mL\u002Fkg normal saline bolus (max 1000 mL) to avoid possible hypotension.\n\n15-19 kg: 750 mg\n\n20-29 kg: 1000 mg\n\n30-39 kg: 1500 mg\n\n\\>40 kg: 2000 mg",[9],[27],"Magnesium within the first hour",{"type":6,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"No Magnesium sulfate within the first hour","The control group will not receive IV magnesium sulfate within the first hour of treatment.",[15],[33],"No magnesium within the first hour",[35],{"name":36,"affiliation":5,"role":37},"Ryan McKee, MD","PRINCIPAL_INVESTIGATOR",[39,44],{"name":36,"role":40,"phone":41,"phoneExt":42,"email":43},"CONTACT","4056308997",null,"ryan-mckee@ouhsc.edu",{"name":45,"role":40,"phone":46,"phoneExt":42,"email":47},"Jaclyn Urquiola Sorzano, DO","7863906297","jaclyn-urquiola@ouhsc.edu",[49],{"facility":50,"status":51,"city":52,"state":53,"zip":54,"country":55,"countryCode":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"Oklahoma Children's Hospital","RECRUITING","Oklahoma City","Oklahoma","73104","United States","US",{"type":58,"coordinates":59},"Point",[60,61],-97.51643,35.46756,{"lat":61,"lon":60},[64],{"name":36,"role":40,"phone":65,"phoneExt":42,"email":66},"405-271-2429","Ryan-McKee@ouhsc.edu",{"type":68,"investigatorFullName":42,"investigatorTitle":42,"investigatorAffiliation":42,"oldNameTitle":42,"oldOrganization":42},"SPONSOR","100526614","early-phase-1-timely-administration-of-iv-magnesium-sulfate-in-patients-with-a-moderate-asthma-exacerbation-100526614",false,"NCT06137040","Timely Administration of IV Magnesium Sulfate in Patients With a Moderate Asthma Exacerbation","Inclusion Criteria:\n\n* Ages 5-17 years old\n* Presents to the ED with a respiratory score in the \"Moderate\" range (6\n* Parent(s)\u002FCaregiver(s) speak English\n\nExclusion Criteria:\n\n* Patients with chronic medical conditions including chronic pulmonary disease (other than asthma), cerebral palsy, congenital heart disease, tracheostomy dependent, myasthenia gravis patients\n* Patients who are pregnant\n* Parent(s)\u002FCaregiver(s) do not speak English","ALL","5 Years","17 Years",{"count":79,"type":80},100,"ESTIMATED","INTERVENTIONAL",[83],"EARLY_PHASE1","This study aims to identify whether early administration of magnesium sulfate in moderate asthma exacerbations can potentially avoid admission, decrease length of stay in the emergency department (ED), decrease length of stay (LOS) in the general hospital floor vs pediatric intensive care unit (PICU), and decrease the need for respiratory support.",[86,87],"Asthma in Children","Asthma Attack",[89,90,91,92],"asthma exacerbation","magnesium sulfate","asthma","asthma attack","2024-12-05",{"date":95,"type":96},"2024-12-06","ACTUAL",{"date":98,"type":96},"2023-11-30",{"date":100,"type":80},"2025-05-31",{"name":5,"class":6},1]