[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100476645":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":26,"centralContacts":30,"locations":39,"responsibleParty":104,"collaborators":107,"id":118,"slug":119,"hasResults":120,"nctId":121,"briefTitle":122,"officialTitle":123,"acronym":21,"eligibilityCriteria":124,"healthyVolunteers":125,"sex":126,"minAge":127,"maxAge":128,"enrollmentInfo":129,"targetDuration":21,"studyType":132,"phases":133,"briefSummary":135,"conditions":136,"keywords":138,"overallStatus":42,"whyStopped":21,"lastUpdateSubmitDate":147,"lastUpdatePostDateStruct":148,"startDateStruct":151,"completionDateStruct":153,"leadSponsor":155,"locationsCount":156},{"fullName":5,"class":6},"Father Flanagan's Boys' Home","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Vocal emotion communication by children and adults with cochlear implants or normal hearing","EXPERIMENTAL","Participants will be native speakers of American English and include pediatric cochlear implant recipients with unilateral or bilateral devices aged 6-19 years, children with normal hearing aged 6-19 years, postlingually deaf adults with cochlear implants, and adults with normal hearing. In Aim 1 participants will listen to emotional speech sounds and identify the talker's intended emotion. In Aim 2 participants will be invited to produce emotional speech by reading out scripted materials or in a more naturalistic conversational setting.",[13,14],"Behavioral: Perception of acoustic cues to emotion","Behavioral: Production of acoustic cues to emotion",[16,22],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":21},"BEHAVIORAL","Perception of acoustic cues to emotion","Using novel methodologies and stimuli comprising both controlled laboratory recordings and materials culled from databases of ecologically valid speech emotions (e.g., from publicly available podcasts), the team aims to collect perceptual data to build a statistical model to test the hypothesis that experience-based changes in emotion identification by pediatric and adult CI recipients is mediated by improvements in cue-optimization.",[9],null,{"type":17,"name":23,"description":24,"armGroupLabels":25,"otherNames":21},"Production of acoustic cues to emotion","The team will acoustically analyze vocal emotion productions by participants, quantify acoustic features of spoken emotions, and obtain behavioral measures of how well normally hearing listeners can identify those emotions.",[9],[27],{"name":28,"affiliation":5,"role":29},"Monita Chatterjee, Ph.D.","PRINCIPAL_INVESTIGATOR",[31,35],{"name":28,"role":32,"phone":33,"phoneExt":21,"email":34},"CONTACT","8474672760","monita.chatterjee@northwestern.edu",{"name":36,"role":32,"phone":37,"phoneExt":21,"email":38},"Dawna E Lewis, Ph.D.","531-355-6607","dawna.lewis@boystown.org",[40,59,73,86],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Arizona State University","RECRUITING","Tempe","Arizona","85287","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-111.90931,33.41477,{"lat":52,"lon":51},[55],{"name":56,"role":32,"phone":57,"phoneExt":21,"email":58},"Xin Luo, Ph.D.","480-965-9251","xinluo@asu.edu",{"facility":60,"status":42,"city":61,"state":62,"zip":63,"country":46,"countryCode":47,"cosmosGeoPoint":64,"geoPoint":68,"contacts":69},"House Institute Foundation","Los Angeles","California","90017",{"type":49,"coordinates":65},[66,67],-118.24368,34.05223,{"lat":67,"lon":66},[70],{"name":71,"role":32,"phone":21,"phoneExt":21,"email":72},"John J Galvin, Ph.D.","jgalvin@hifla.org",{"facility":74,"status":75,"city":76,"state":77,"zip":78,"country":46,"countryCode":47,"cosmosGeoPoint":79,"geoPoint":83,"contacts":84},"Northwestern University","NOT_YET_RECRUITING","Evanston","Illinois","60208",{"type":49,"coordinates":80},[81,82],-87.69006,42.04114,{"lat":82,"lon":81},[85],{"name":28,"role":32,"phone":21,"phoneExt":21,"email":34},{"facility":87,"status":42,"city":88,"state":89,"zip":90,"country":46,"countryCode":47,"cosmosGeoPoint":91,"geoPoint":95,"contacts":96},"Boys Town National Research Hospital","Omaha","Nebraska","68131",{"type":49,"coordinates":92},[93,94],-95.94043,41.25626,{"lat":94,"lon":93},[97,100,101],{"name":28,"role":32,"phone":98,"phoneExt":21,"email":99},"531-355-5069","monita.chatterjee@boystown.org",{"name":36,"role":32,"phone":37,"phoneExt":21,"email":38},{"name":102,"role":103,"phone":21,"phoneExt":21,"email":21},"Sophie E Ambrose, Ph.D.","SUB_INVESTIGATOR",{"type":29,"investigatorFullName":105,"investigatorTitle":106,"investigatorAffiliation":5,"oldNameTitle":21,"oldOrganization":21},"Monita Chatterjee","Senior Scientist",[108,109,111,113,116],{"name":41,"class":6},{"name":60,"class":110},"UNKNOWN",{"name":112,"class":6},"University of Nebraska",{"name":114,"class":115},"National Institute on Deafness and Other Communication Disorders (NIDCD)","NIH",{"name":117,"class":115},"Office of Behavioral and Social Sciences Research (OBSSR)","100476645","early-phase-1-vocal-emotion-communication-with-cochlear-implants-100476645",false,"NCT05486637","Vocal Emotion Communication With Cochlear Implants","Perception and Production of Emotional Prosody With Cochlear Implants","Inclusion Criteria:\n\n* Prelingually deaf children with cochlear implants\n\n  * Postlingually deaf adults with cochlear implants\n  * Normally hearing children\n  * Normally hearing adults\n\nExclusion Criteria:\n\n* Non-native speakers of American English\n\n  * Prelingually deaf individuals who receive cochlear implants after age 12\n  * Adults unable to pass a basic cognitive screen",true,"ALL","6 Years","80 Years",{"count":130,"type":131},255,"ESTIMATED","INTERVENTIONAL",[134],"EARLY_PHASE1","Patients with hearing loss who use cochlear implants (CIs) show significant deficits and strong unexplained intersubject variability in their perception and production of spoken emotions in speech. This project will investigate the hypothesis that \"cue-weighting\", or how patients utilize the different acoustic cues to emotion, accounts for significant variance in emotional communication with CIs. The results will focus on children with CIs, but parallel measures in postlingually deaf adults with CIs will be made, ensuring that results of these studies benefit social communication by CI patients across the lifespan by informing the development of technological innovations and improved clinical protocols.",[137],"Cochlear Hearing Loss",[139,140,141,142,143,144,145,146],"Emotional prosody","Acoustic cues","Perception","Production","Children","Development","Cochlear Implant","Hearing Loss","2025-09-16",{"date":149,"type":150},"2025-09-19","ACTUAL",{"date":152,"type":150},"2022-07-01",{"date":154,"type":131},"2027-06-30",{"name":5,"class":6},4]